Human Health Risk Assessment for Exposure to Potentially Toxic Elements in Polluted Rivers in the Ecuadorian Amazon
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Area
2.2. Human Health Risk Assessment
2.2.1. Data Collection and Analyses
2.2.2. Exposure Parameters
2.2.3. Risk Characterization
2.3. Deterministic Approach
2.4. Probabilistic Approach: Monte Carlo Simulation (MCS)
Sensitivity Analysis
Parameters | Deterministic Approach | Probabilistic Approach | Reference | ||
---|---|---|---|---|---|
Point Estimate (RME) | Distribution | Values | |||
EF | Exposure frequency-adults and children (day/year) | 120 | Triangular | 120 (26–260) | |
EDa | Exposure duration-adults (year) | 30 | Lognormal | 11.36 ± 13.72 | Israeli et al. [49] |
EDc | Exposure duration-children (year) | 6 | Uniform | 1–6 | Spence and Walden [50] |
ET | Exposure time-adults and children (hour/event) | 2.6 | Triangular | 2.6 (0.5–6) | |
SAa | Skin surface area (swimming)-adults (cm2) | 23,000 | Normal | 18,400 ± 2300 | Anderson et al. [51] |
SAc | Skin surface area (swimming)-children (cm2) | 7280 | Normal | 6800 ± 600 | Carr [52]; Spence and Walden [50] |
BWa | Body weight-adults (kg) | 70 | Normal | 72 ± 15.9 | Carr [52] |
BWc | Body weight-children (kg) | 15 | Normal | 15.6 ± 3.7 | Anderson et al. [51] |
IRwa | Ingestion rate of water-adults (L/event) | 0.053 | - | 0.053 | USEPA [39] |
IRwc | Ingestion rate of water-children (L/event) | 0.090 | - | 0.090 | |
IRsa | Ingestion rate of sediments-adults (mg/event) | 12.5 | - | 12.5 | Goldblum et al. [53] |
IRsc | Ingestion rate of sediments-children (mg/event) | 50 | - | 50 | |
ATnc | Averaging time non-carcinogen (day) | 365 × ED | - | 365 × ED | USEPA [21] |
ATca | Averaging time carcinogen (day) | 365 × 70 | - | 365 × 70 | USEPA [21] |
AFa | Adherence factor-adults (mg/cm2) | 0.07 | - | 0.07 | USEPA [21] |
AFc | Adherence factor-children (mg/cm2) | 0.2 | - | 0.2 | USEPA [21] |
ABS | Dermal absorption factor (unit-less) | 0.001 | - | 0.001 | Wang et al. [9]; USEPA [39] |
Kp: | Permeability constant (cm/hour) | Al, Cd, Cr, Cu, Hg = 0.001, Pb = 0.0001, Hg, Ni = 0.0002; Zn = 0.0006 | - | Al, Cd, Cr, Cu, Hg = 0.001, Pb = 0.0001, Hg, Ni = 0.0002; Zn = 0.0006 | RAIS [40] |
3. Results
3.1. Deterministic Approach
Point Risk Maps
3.2. Probabilistic Approach: Monte Carlo Simulation (MCS)
3.2.1. Non-Carcinogenic Risk
3.2.2. Carcinogenic Risk
3.2.3. Sensitivity Analysis
4. Discussion
4.1. Potential Impacts of PTEs on Human Health
Deterministic and Probabilistic Quantification
4.2. Environmental Management and Public Policy
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Surface Water (µg/L) | Sediments (mg/kg) | |||||||
---|---|---|---|---|---|---|---|---|
Min. | p50 | Max. | Std. dev | Min. | p50 | Max. | Std. dev | |
Al | 0.10 | 0.30 | 303.60 | 83.90 | 2880.80 | 12,365.60 | 269,301.00 | 73,197.12 |
Cd | 1.70 | 3.00 | 46.00 | 13.60 | 1.40 | 2.70 | 20.10 | 4.84 |
Cr | 4.90 | 19.40 | 238.30 | 99.82 | 2.70 | 8.90 | 38.80 | 9.63 |
Cu | 2.80 | 19.20 | 135.30 | 72.23 | 2.40 | 14.35 | 50.80 | 14.78 |
Hg | 0.50 | 6.70 | 11.20 | 3.97 | 0.10 | 0.10 | 0.40 | 0.13 |
Ni | 18.10 | 86.85 | 155.60 | 97.23 | 0.90 | 5.60 | 17.20 | 4.53 |
Pb | 0.70 | 39.30 | 133.10 | 48.14 | 1.00 | 3.15 | 11.00 | 3.10 |
Zn | 2.40 | 13.05 | 712.00 | 186.17 | 17.80 | 48.30 | 233.70 | 55.06 |
Surface Waters | Sediments | |||
---|---|---|---|---|
Adults | Children | Adults | Children | |
HI | 1.85 | 4.83 | 1.99 × 102 | 2.66 × 103 |
TCR | 4.31 × 10−5 | 3.42 × 10−4 | 5.67 × 10−3 | 1.06 × 10−3 |
Media | PTEs | Fitted Distribution | Distribution Parameters | AD | KS |
---|---|---|---|---|---|
Surface water | Al | Cauchy | Location = 0.23, Scale = 0.14 | 3.18 | 0.27 |
Cd | Cauchy | Location = 2.83, Scale = 0.75 | 1.05 | 0.20 | |
Cr | Cauchy | Location = 14.40, Scale = 10.85 | 0.70 | 0.27 | |
Hg | Lognormal | Mean = 1.38, sd = 1.09 | 0.58 | 0.29 | |
Pb | Logistic | Location = 39.70, Scale = 26.30 | 0.55 | 0.19 | |
Zn | Lognormal | Mean = 2.71, sd = 1.52 | 0.37 | 0.13 | |
Sediments | Al | Lognormal | Mean = 9.81, sd = 1.24 | 0.45 | 0.17 |
Cd | Lognormal | Mean = 1.17, sd = 0.67 | 0.67 | 0.24 | |
Cr | Logistic | Location = 10.86, Scale = 4.74 | 0.56 | 0.16 | |
Cu | Lognormal | Mean = 2.44, sd = 0.95 | 0.29 | 0.13 | |
Hg | Exponential | Rate = 6.25 | 1.11 | 0.46 | |
Ni | Logistic | Location = 6.56, Scale = 2.37 | 0.82 | 0.15 | |
Pb | Normal | Mean = 4.06, sd = 2.99 | 0.70 | 0.19 | |
Zn | Lognormal | Mean = 3.86, sd = 0.68 | 0.26 | 0.11 |
Surface Water | Sediments | |||
---|---|---|---|---|
Adults | Children | Adults | Children | |
HI | 2.03 × 103 | 3.52 × 103 | 3.69 × 104 | 2.04 × 105 |
TCR | 2.09 × 10−4 | 7.85 × 10−5 | 1.67 × 10−3 | 8.09 × 10−3 |
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Jiménez-Oyola, S.; Escobar Segovia, K.; García-Martínez, M.-J.; Ortega, M.; Bolonio, D.; García-Garizabal, I.; Salgado, B. Human Health Risk Assessment for Exposure to Potentially Toxic Elements in Polluted Rivers in the Ecuadorian Amazon. Water 2021, 13, 613. https://doi.org/10.3390/w13050613
Jiménez-Oyola S, Escobar Segovia K, García-Martínez M-J, Ortega M, Bolonio D, García-Garizabal I, Salgado B. Human Health Risk Assessment for Exposure to Potentially Toxic Elements in Polluted Rivers in the Ecuadorian Amazon. Water. 2021; 13(5):613. https://doi.org/10.3390/w13050613
Chicago/Turabian StyleJiménez-Oyola, Samantha, Kenny Escobar Segovia, María-Jesús García-Martínez, Marcelo Ortega, David Bolonio, Iker García-Garizabal, and Bryan Salgado. 2021. "Human Health Risk Assessment for Exposure to Potentially Toxic Elements in Polluted Rivers in the Ecuadorian Amazon" Water 13, no. 5: 613. https://doi.org/10.3390/w13050613