Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Procedures
2.2.1. Anthropometrics
2.2.2. Air-Displacement Plethysmography (ADP)
2.3. Statistical Analyses
3. Results
3.1. Subject Characteristics
3.2. Comparison of the Methods
3.3. Inter-Rater Reliability Tests–Skinfold Thickness Measurements
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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1 Month | 4 Months | 6 Months | 2 Years | |
---|---|---|---|---|
n = 245 | n = 238 | n = 235 | n = 173 | |
Boys [n (%)] | 113 (46) | 112 (47) | 111 (47) | 82 (47) |
Caucasian [n (%)] | 213 (87) | 208 (87) | 205 (87) | 151 (87) |
Age (mo) | 1.0 ± 0.3 | 3.9 ± 0.1 | 6.0 ± 0.1 | 24.1 ± 0.5 |
Body weight (gram) | 4207 ± 536 | 6598 ± 685 | 7692 ± 834 | 12415 ± 1315 |
Length/height (cm) | 54.5 ± 2.2 | 63.7 ± 2.0 | 67.9 ± 2.2 | 86.8 ± 2.8 |
Formula-fed a [n (%)] | 178 (73) | 173 (73) | 170 (72) | NA |
Skinfold thickness measurements | ||||
n = 242−235 | n = 237−236 | n = 235 | n = 169−168 | |
∑SFT (mm) b | 23.2 ± 3.8 | 29.4 ± 5.2 | 29.0 ± 5.6 | 27.3 ± 5.2 |
n = 235 | n = 235 | n = 235 | n = 167 | |
Body density (kg/L) | 1.0274 ± 0.0050 | 1.0215 ± 0.0055 | 1.0228 ± 0.0060 | 1.0286 ± 0.0057 |
Fat mass% | 20.0 ± 2.8 | 23.7 ± 3.0 | 23.2 ± 3.3 | 21.4 ± 3.0 |
Air-displacement plethysmography | ||||
n = 231 | n = 230 | n = 219 | n = 103 | |
Body density | 1.0330 ± 0.0073 | 1.0185 ± 0.0077 | 1.0184 ± 0.0079 | 1.0327 ± 0.0154 |
Fat mass% | 16.8± 4.0 | 25.4 ± 4.3 | 25.8 ± 4.4 | 20.7 ± 8.2 |
1 Month | 4 Months | 6 Months | 2 Years | |
---|---|---|---|---|
n | 225 | 229 | 219 | 102 |
Mean difference (bias) | −3.05 | 1.70 | 2.65 | −0.47 |
Limits of agreement (CI95%) | 3.12 −9.21 | 8.86 −546 | 10.25 −4.96 | 13.29 −14.23 |
Difference 1 | −3.15 | 1.70 | 2.63 | −0.67 |
P1 | <0.001 | <0.001 | <0.001 | 0.112 |
(CI95%) | (−3.75, −2.54) | (1.10, 2.31) | (2.02, 3.24) | (−1.49, 0.16) |
ICC 2 | 0.42 | 0.47 | 0.42 | 0.33 |
1 month | 4 months | 6 months | 2 years |
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Kouwenhoven, S.M.P.; Antl, N.; Twisk, J.W.R.; Koletzko, B.V.; Finken, M.J.J.; van Goudoever, J.B. Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography. Life 2021, 11, 75. https://doi.org/10.3390/life11020075
Kouwenhoven SMP, Antl N, Twisk JWR, Koletzko BV, Finken MJJ, van Goudoever JB. Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography. Life. 2021; 11(2):75. https://doi.org/10.3390/life11020075
Chicago/Turabian StyleKouwenhoven, Stefanie M. P., Nadja Antl, Jos W. R. Twisk, Berthold V. Koletzko, Martijn J. J. Finken, and Johannes B. van Goudoever. 2021. "Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography" Life 11, no. 2: 75. https://doi.org/10.3390/life11020075