Physical Activity and Bone Vascularization: A Way to Explore in Bone Repair Context?
Abstract
:1. Introduction
2. Physical Activities and Their Effects on Angiogenesis and Osteogenesis
3. Some Growth and Transcriptional Factors Involved in Osteogenesis/Angiogenesis Induced by Physical Activity
4. Vascularization and Bone Repair
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Type of Exercise | Duration | Species | Site | Parameters | Effects | References |
---|---|---|---|---|---|---|
Treadmill walking | 10–12 weeks | Rat | Femur Tibia Fibula | Blood flow and vascular conductance | + + + | [20] |
Treadmill exercise | 10–12 weeks | Rat | Femur | Bone marrow blood flow | + | [21] |
Vasodilatation response | + | |||||
Endothelium signaling pathways | + | |||||
Swimming | 8 weeks | Rat | Femur | Bone microvascularity Bone capillary vascularity | + + + | [22] |
Climbing resistance exercise | 8 weeks | Rat | Aorta | Endothelin-1 concentration Expression of the endothelial nitric oxide (eNOS) protein | + + + | [23] |
Swimming | 8 weeks | Rat | Aorta | Endothelin-1 concentration Expression eNOS protein | + + + | [23] |
Treadmill running | 7 weeks 3 weeks | Rat Mouse | Humerus Femur Tibia | Vascular adaptations Circulating red cell volume Circulating blood volume | + + + | [24] |
Treadmill exercise | 6 weeks | Rat | Femur | Diameter and volume of blood vessels Expression of eNOS in femoral vessels | + + + | [25] |
Treadmill running | 5 weeks | Rat | Tibia | Number of vessels in the proximal metaphysis VEGF receptor 1 mRNA | + + + | [26] |
Treadmill running | 4 weeks | Rat | Femur | Total bone, proximal, diaphyseal, callus, and muscle blood flows | + + + | [27] |
Treadmill running | 3 weeks | Mouse | Bone marrow | Numbers of circulating EPCs EPCs in the bone marrow VEGF serum level | + + + | [28] |
Bicycle ergometer training | 4 weeks | Human | Blood | Numbers of circulating EPCs | + + + | [28] |
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Wazzani, R.; Pallu, S.; Bourzac, C.; Ahmaïdi, S.; Portier, H.; Jaffré, C. Physical Activity and Bone Vascularization: A Way to Explore in Bone Repair Context? Life 2021, 11, 783. https://doi.org/10.3390/life11080783
Wazzani R, Pallu S, Bourzac C, Ahmaïdi S, Portier H, Jaffré C. Physical Activity and Bone Vascularization: A Way to Explore in Bone Repair Context? Life. 2021; 11(8):783. https://doi.org/10.3390/life11080783
Chicago/Turabian StyleWazzani, Rkia, Stéphane Pallu, Céline Bourzac, Saïd Ahmaïdi, Hugues Portier, and Christelle Jaffré. 2021. "Physical Activity and Bone Vascularization: A Way to Explore in Bone Repair Context?" Life 11, no. 8: 783. https://doi.org/10.3390/life11080783