Long-Term Macular Vascular Changes after Primary Rhegmatogenous Retinal Detachment Surgery Resolved with Different Tamponade or Different Surgical Techniques
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Design and Setting of the Study
2.2. Participants
2.3. Surgical Procedure
2.4. Functional Parameter: Best-Corrected Visual Acuity
2.5. Perfusion Parameters: OCTA Image Acquisition and Analysis
2.6. Statistical Analysis
3. Results
3.1. Macula-ON Group
3.2. Macula-OFF Group
3.3. Surgery Subgroup Analysis
3.4. OCT Findings
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | |
---|---|
Patients, n | 82 |
Age, mean yrs ± SD | 63 ± 12 |
Male, n (%) | 50 (61) |
Diabetes | 6 (7.3) |
Hypertension | 38 (46.3) |
Pre-operative factors | |
Right eye: Left eye, % | 55: 45 |
Macula OFF, n (%) | 49 (59.8) |
Pseudophakic | 20 (24.4) |
Intraoperative factors | |
Type of surgery, n (%) | |
PPV | 70 (85.4) |
SB | 12 (14.6) |
Type of surgery | |
Gas | 65 (79.3) |
SO | 17 (20.7) |
Combined cataract surgery | 42 (51.2) |
360° laser | 12 (14.6) |
Operation time, min (mean ± SD) | 91.27 ± 34.9 |
Post-operative factors | |
Duration of SO tamponade, months (mean ± SD) | 4.81 ± 1.8 |
Hypotony (IOP < 5 mmHg) | 0 |
Secondary glaucoma (IOP > 21 mmHg), n (%) | 8 (9.8) |
Intraretinal cysts, % | 12 (14.6) |
Follow-up period (months; m ± SD) | 13.1 ± 2 |
BCVA-Post | Macula-ON Group | Macula-OFF Group | ||
---|---|---|---|---|
β ± SE | p-Value | β ± SE | p-Value | |
Type of surgery | −0.009 ± 0.043 | 0.841 | −0.059 ± 0.084 | 0.487 |
Tamponade | 0.273 ± 0.088 | 0.004 * | −0.007 ± 0.119 | 0.955 |
Follow-up period | 0.002 ± 0.005 | 0.640 | −0.001 ± 0.007 | 0.878 |
Macula-ON Group | Macula-OFF Group | |||||
---|---|---|---|---|---|---|
Study Eyes | Control Eyes | p-Value | Study Eyes | Control Eyes | p-Value | |
CENTRAL SCP VD | 30.20 ± 5.70 | 32.22 ± 5.66 | 0.002 * | 28.31 ± 5.79 | 30.32 ± 5.78 | 0.002 * |
INF SCP VD | 40.78 ± 4.51 | 41.80 ± 3.52 | 0.275 | 40.33 ± 3.64 | 42.24 ± 2.38 | 0.002 * |
NAS SCP VD | 39.45 ± 4.48 | 40.90 ± 3.77 | 0.038 * | 38.51 ± 3.73 | 40.19 ± 3.18 | 0.010 * |
SUP SCP VD | 40.32 ± 4.34 | 42.14 ± 2.78 | 0.030 * | 39.65 ± 3.31 | 41.42 ± 2.88 | 0.002 * |
TEMP SCP VD | 38.42 ± 3.78 | 39.87 ± 3.35 | 0.056 | 38.06 ± 2.85 | 39.76 ± 2.56 | 0.000 * |
CENTRAL DCP VD | 30.30 ± 8.90 | 30.67 ± 8.15 | 0.752 | 28.76 ± 7.44 | 29.05 ± 8.15 | 0.784 |
INF DCP VD | 42.76 ± 3.41 | 42.61 ± 2.65 | 0.829 | 42.08 ± 3.08 | 42.82 ± 2.99 | 0.185 |
NAS DCP VD | 42.74 ± 3.94 | 43.00 ± 2.36 | 0.698 | 41.54 ± 2.79 | 42.37 ± 2.93 | 0.117 |
SUP DCP VD | 42.28 ± 4.06 | 43.03 ± 2.47 | 0.307 | 41.85 ± 2.83 | 42.40 ± 2.63 | 0.176 |
TEMP DCP VD | 41.83 ± 3.69 | 41.96 ± 2.61 | 0.842 | 41.43 ± 2.97 | 41.58 ± 2.70 | 0.731 |
CENTRAL SCP VLD | 16.17 ± 2.83 | 17.65 ± 2.86 | 0.001 * | 15.23 ± 2.87 | 16.53 ±2.96 | 0.001 * |
INF SCP VLD | 21.01 ± 3.52 | 21.70 ± 3.69 | 0.221 | 21.11 ± 3.66 | 22.24 ± 3.35 | 0.004 * |
NAS SCP VLD | 20.88 ± 3.33 | 21.83 ± 3.25 | 0.086 | 21.04 ± 3.29 | 21.92 ± 2.99 | 0.032 * |
SUP SCP VLD | 20.55 ± 3.48 | 21.59 ± 4.04 | 0.090 | 20.73 ± 3.27 | 22.08 ± 3.65 | 0.001 * |
TEMP SCP VLD | 20.18 ± 2.98 | 20.78 ± 3.55 | 0.259 | 20.46 ± 2.77 | 21.50 ± 2.85 | 0.002 * |
CENTRAL DCP VLD | 16.54 ± 4.40 | 16.80 ± 4.58 | 0.739 | 16.10 ± 4.25 | 16.30 ± 4.72 | 0.766 |
INF DCP VLD | 25.29 ± 3.89 | 24.66 ± 4.04 | 0.288 | 25.06 ± 3.95 | 25.28 ± 3.90 | 0.598 |
NAS DCP VLD | 24.66 ± 3.64 | 25.06 ± 3.72 | 0.537 | 24.82 ± 3.60 | 25.01 ± 3.46 | 0.655 |
SUP DCP VLD | 24.78 ± 3.74 | 25.10 ± 4.46 | 0.600 | 24.90 ± 3.65 | 25.41 ± 3.79 | 0.089 |
TEMP DCP VLD | 24.30 ± 3.17 | 24.12 ± 3.62 | 0.747 | 24.34 ± 3.34 | 24.26 ± 3.40 | 0.796 |
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Gironi, M.; D’Aloisio, R.; Verdina, T.; Vivarelli, C.; Leonelli, R.; Kaleci, S.; Toto, L.; Mastropasqua, R. Long-Term Macular Vascular Changes after Primary Rhegmatogenous Retinal Detachment Surgery Resolved with Different Tamponade or Different Surgical Techniques. Life 2022, 12, 1525. https://doi.org/10.3390/life12101525
Gironi M, D’Aloisio R, Verdina T, Vivarelli C, Leonelli R, Kaleci S, Toto L, Mastropasqua R. Long-Term Macular Vascular Changes after Primary Rhegmatogenous Retinal Detachment Surgery Resolved with Different Tamponade or Different Surgical Techniques. Life. 2022; 12(10):1525. https://doi.org/10.3390/life12101525
Chicago/Turabian StyleGironi, Matteo, Rossella D’Aloisio, Tommaso Verdina, Chiara Vivarelli, Riccardo Leonelli, Shaniko Kaleci, Lisa Toto, and Rodolfo Mastropasqua. 2022. "Long-Term Macular Vascular Changes after Primary Rhegmatogenous Retinal Detachment Surgery Resolved with Different Tamponade or Different Surgical Techniques" Life 12, no. 10: 1525. https://doi.org/10.3390/life12101525