The Enclosed Intestinal Microbiome: Semiochemical Signals from the Precambrian and Their Disruption by Heavy Metal Pollution †
Abstract
:1. Introduction: Microbiome-Function Deficiency Disease
2. Of Germs and Genes: The Invertebrates
3. The Vertebrates
4. Flexibility and Diversity: Germs in the Environment
5. Parallel Interactions within the Intestinal Host-Guest Relationship
5.1. Semiochemical Production
5.2. The Microbiota (or Microbiome)–Gut–Brain Axis
5.3. Regulation of the Flow of Nutrition
5.4. Maternal Microbial Inheritance
5.5. Microbial Sentinel Cells
6. Semiochemicals: From Single Cells to Multicellular Animals
7. Microbial Sentinel Cells: Potential Partners of the Immune System
8. The Loss of Immune-System Selectivity
9. Environmental Insults and the Microbiome
10. Cancer
11. Conclusions: The Amelioration of Non-Communicable Disease
- (a)
- Develop methods to check the microbiome function of people not exposed to heavily polluted environments and;
- (b)
- Confirm the role, if any, of unicellular eukaryotes, as well as prokaryotes. Finally,
- (c)
- Consider the benefits of an ingestible sensor for the measurement of semiochemicals in order to assist the amelioration of any microbiome-function deficiency in individuals and their children.
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Smith, D.; Palacios-Pérez, M.; Jheeta, S. The Enclosed Intestinal Microbiome: Semiochemical Signals from the Precambrian and Their Disruption by Heavy Metal Pollution. Life 2022, 12, 287. https://doi.org/10.3390/life12020287
Smith D, Palacios-Pérez M, Jheeta S. The Enclosed Intestinal Microbiome: Semiochemical Signals from the Precambrian and Their Disruption by Heavy Metal Pollution. Life. 2022; 12(2):287. https://doi.org/10.3390/life12020287
Chicago/Turabian StyleSmith, David, Miryam Palacios-Pérez, and Sohan Jheeta. 2022. "The Enclosed Intestinal Microbiome: Semiochemical Signals from the Precambrian and Their Disruption by Heavy Metal Pollution" Life 12, no. 2: 287. https://doi.org/10.3390/life12020287