Optical Coherence Tomography Angiography of the Intestine: How to Prevent Motion Artifacts in Open and Laparoscopic Surgery?
Abstract
:1. Introduction
2. Materials and Methods
2.1. Vacuum Tissue Stabilizer
2.2. Experimental Study Design
2.3. Device Security Control
2.4. Histological Examination
2.5. OCTA Device and Blood Vessels Quantification
2.6. Quality Evaluation of the OCTA Images
2.7. Statistical Data Processing
3. Results
3.1. OCTA Image Quality in Open Surgery
3.2. OCTA Image Quality in Laparoscopic Surgery
3.3. Safety of the Vacuum Stabilization Method for Intestinal Wall Tissues
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Group, Stage of Experiment | Image Quality Class | |||||
---|---|---|---|---|---|---|
1 Class | 2 Class | 3 Class | ||||
MP * | VS ** | MP | VS | MP | VS | |
Norma (n = 200), n | 14 (7%) | 92 (46%) | 74 (37%) | 92 (46%) | 112 (56%) | 16 (8%) |
Ischemia (n = 200), n | 8 (4%) | 48 (24%) | 56 (28%) | 114 (57%) | 136 (68%) | 38 (19%) |
Normal Intestine, Experiment Series 1 | Ischemic Intestine, Experiment Series 1 | Normal Intestine, Experiment Series 2 | Ischemic Intestine, Experiment Series 2 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Vessel diameter | L1 | L2 | L3 | L1 | L2 | L3 | L1 | L2 | L3 | L1 | L2 | L3 |
No vacuum | 3.6 [3.1; 4.2] | 14.5 [12.5; 16.1] | 13.1 [12.1; 14.3] | 3.3 [3.2; 4.4] | 13.8 [12.7; 17.2] | 12.4 [12.2; 13.9] | 3.0 [2.9; 3.6] | 14.4 [13.2; 14.7] | 15.8 [12.9; 15.9] | 4.2 [4.1; 4.8] | 17.0 [16.3; 17.5] | 12.4 [12.2; 13.9] |
Vacuum stabilizer | 4.3 [3.9; 4.6] | 17.8 [16.5; 19.5] | 10.7 [9.7; 11.5] | 2.6 [2.0; 3.4] | 10.5 [8.7; 13.8] | 10.7 [10.2; 11.3] | 3.7 [3.6; 3.9] | 15.4 [15.3; 16.0] | 12.9 [11.2; 13.5] | 3.5 [2.8; 4.0] | 14.6 [12,1; 16.0] | 10.4 [9.9; 10.8] |
Wilcoxon signed-rank test | 0.003 | 0.001 | 0.001 | 0.008 | 0.004 | 0.002 | 0.239 | 0.025 | 0.138 | 0.043 | 0.128 | 0.034 |
Group, Stage of Experiment | Image Quality Class | |||||
---|---|---|---|---|---|---|
1 Class | 2 Class | 3 Class | ||||
MP * | VS ** | MP | VS | MP | VS | |
Norma (n = 200), n | 12 (6%) | 42 (21%) | 32 (16%) | 88 (44%) | 156 (78%) | 70 (35%) |
Ischemia (n = 200), n | 4 (2%) | 28 (14%) | 24 (12%) | 82 (41%) | 172 (86%) | 90 (45%) |
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Ryabkov, M.; Sizov, M.; Bederina, E.; Zarubenko, P.; Peretyagin, P.; Moiseev, A.; Vorobiev, A.; Gladkova, N.; Zaitsev, V.; Kiseleva, E. Optical Coherence Tomography Angiography of the Intestine: How to Prevent Motion Artifacts in Open and Laparoscopic Surgery? Life 2023, 13, 705. https://doi.org/10.3390/life13030705
Ryabkov M, Sizov M, Bederina E, Zarubenko P, Peretyagin P, Moiseev A, Vorobiev A, Gladkova N, Zaitsev V, Kiseleva E. Optical Coherence Tomography Angiography of the Intestine: How to Prevent Motion Artifacts in Open and Laparoscopic Surgery? Life. 2023; 13(3):705. https://doi.org/10.3390/life13030705
Chicago/Turabian StyleRyabkov, Maksim, Mikhail Sizov, Evgeniya Bederina, Polina Zarubenko, Peter Peretyagin, Alexander Moiseev, Aleksander Vorobiev, Natalia Gladkova, Vladimir Zaitsev, and Elena Kiseleva. 2023. "Optical Coherence Tomography Angiography of the Intestine: How to Prevent Motion Artifacts in Open and Laparoscopic Surgery?" Life 13, no. 3: 705. https://doi.org/10.3390/life13030705