Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta25–35-Treated C6 Glial Cells
Abstract
:1. Introduction
2. Results
2.1. Effects of FCJM Extract and Fractions on Cell Viability
2.2. Effects of FCJM Extract and Fractions on ROS Production
2.3. Regulation of the HO-1 Protein Expression Level by EFCJM in Aβ25–35-Treated C6 Glial Cells
2.4. Regulation of the Apoptosis-Related Protein Expression Level by EFCJM in Aβ25–35-Treated C6 Glial Cells
2.5. Regulation of the RAGE and IDE Protein Expression Level by EFCJM in Aβ25–35-Treated C6 Glial Cells
2.6. Regulation of the Amyloidogenic Pathway-Related Protein Expression Level by EFCJM in Aβ25–35-Treated C6 Glial Cells
3. Discussion
4. Materials and Methods
4.1. Materials
4.2. Sample Preparation
4.3. Cell Culture
4.4. Cell Viability Assay
4.5. Measurement of ROS Production
4.6. Western Blot Analysis
4.7. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Pang, Q.Q.; Lee, S.; Cho, E.J.; Kim, J.-H. Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta25–35-Treated C6 Glial Cells. Life 2023, 13, 1453. https://doi.org/10.3390/life13071453
Pang QQ, Lee S, Cho EJ, Kim J-H. Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta25–35-Treated C6 Glial Cells. Life. 2023; 13(7):1453. https://doi.org/10.3390/life13071453
Chicago/Turabian StylePang, Qi Qi, Sanghyun Lee, Eun Ju Cho, and Ji-Hyun Kim. 2023. "Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta25–35-Treated C6 Glial Cells" Life 13, no. 7: 1453. https://doi.org/10.3390/life13071453