Towards a Responsible Transition to Learning Healthcare Systems in Precision Medicine: Ethical Points to Consider
Abstract
:1. Introduction
2. The Levers of Learning Healthcare Systems in Precision Medicine
2.1. Changing the Scope of the Tests to Measure Individual Variability
2.2. Changing the Treatments that Are Prescribed on the Basis of These Tests
2.3. Changing the Handling of Data that Link Variability and Treatment to Outcomes
3. Discussion
3.1. Consent
3.2. Oversight
3.3. Public Engagement and Accountability
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Wouters, R.H.P.; van der Graaf, R.; Rigter, T.; Bunnik, E.M.; Ploem, M.C.; de Wert, G.M.W.R.; Dondorp, W.J.; Cornel, M.C.; Bredenoord, A.L. Towards a Responsible Transition to Learning Healthcare Systems in Precision Medicine: Ethical Points to Consider. J. Pers. Med. 2021, 11, 539. https://doi.org/10.3390/jpm11060539
Wouters RHP, van der Graaf R, Rigter T, Bunnik EM, Ploem MC, de Wert GMWR, Dondorp WJ, Cornel MC, Bredenoord AL. Towards a Responsible Transition to Learning Healthcare Systems in Precision Medicine: Ethical Points to Consider. Journal of Personalized Medicine. 2021; 11(6):539. https://doi.org/10.3390/jpm11060539
Chicago/Turabian StyleWouters, Roel H. P., Rieke van der Graaf, Tessel Rigter, Eline M. Bunnik, M. Corrette Ploem, Guido M. W. R. de Wert, Wybo J. Dondorp, Martina C. Cornel, and Annelien L. Bredenoord. 2021. "Towards a Responsible Transition to Learning Healthcare Systems in Precision Medicine: Ethical Points to Consider" Journal of Personalized Medicine 11, no. 6: 539. https://doi.org/10.3390/jpm11060539
APA StyleWouters, R. H. P., van der Graaf, R., Rigter, T., Bunnik, E. M., Ploem, M. C., de Wert, G. M. W. R., Dondorp, W. J., Cornel, M. C., & Bredenoord, A. L. (2021). Towards a Responsible Transition to Learning Healthcare Systems in Precision Medicine: Ethical Points to Consider. Journal of Personalized Medicine, 11(6), 539. https://doi.org/10.3390/jpm11060539