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Open AccessReview
Novel Challenges and Therapeutic Options for Pulmonary Embolism and Deep Vein Thrombosis
by
Chiara Cavallino
Chiara Cavallino *
,
Marco Franzino
Marco Franzino
,
Mohamed Abdirashid
Mohamed Abdirashid ,
Ludovica Maltese
Ludovica Maltese
,
Elodi Bacci
Elodi Bacci ,
Francesco Rametta
Francesco Rametta and
Fabrizio Ugo
Fabrizio Ugo
Dr. Fabrizio Ugo is the Director of the Hemodynamics Facility at the Sant'Andrea Hospital in and out [...]
Dr. Fabrizio Ugo is the Director of the Hemodynamics Facility at the Sant'Andrea Hospital in Vercelli and carries out outpatient cardiology and consultancy activities at private centers, particularly with respect to sports cardiology. He is a specialist surgeon in cardiology and has a Master's in Sports Cardiology. He obtained a degree in Medicine and Surgery from the University of Eastern Piedmont “A. Avogadro” of Novara and specialized in cardiology, with honors at the University of Parma. He continued his training by obtaining a level II Master's degree in Sports Cardiology at the Faculty of Cardiology of the University of Padua. Moreover, he is the author of numerous abstracts and scientific works in the field of cardiovascular research, and he is a speaker at the most important national and international conferences on the topic. He mainly deals with myocardial infarction, mitral valve, aortic stenosis, coronary arteries, sports cardiology, coronary angiography, and coronary angioplasty.
Cardiology Division, Sant’Andrea Hostpital, 13100 Vercelli, Italy
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2024, 14(8), 885; https://doi.org/10.3390/jpm14080885 (registering DOI)
Submission received: 28 June 2024
/
Revised: 23 July 2024
/
Accepted: 13 August 2024
/
Published: 21 August 2024
Abstract
Acute pulmonary embolism (PE), often resulting from deep vein thrombosis (DVT), is the third most frequent cause of cardiovascular death and is associated with increasing incidence, causing considerable morbidity and mortality. This review aims to evaluate the efficacy, safety, and outcomes of treatment options in the management of acute PE and DVT, encompassing both established and emerging technologies, such as catheter-directed thrombolysis, aspiration thrombectomy, and other endovascular techniques. A comprehensive literature review was conducted, assessing clinical studies, trials, and case reports that detail the use of percutaneous interventions for PE and DVT and analyzing the advantages and disadvantages of each percutaneous system. Several percutaneous treatments have shown promising results, especially in cases where rapid thrombus resolution is critical, such as in high- and intermediate–high-risk patients. The incidence of major complications, such as bleeding, remains a consideration, though it is generally manageable with proper patient selection and technique. It is fundamentally important to tailor the specific treatment strategy to the clinical and anatomical characteristics of each patient. Percutaneous treatments for acute PE and DVT represent valuable options in the therapeutic arsenal, offering enhanced outcomes in appropriately selected patients. Ongoing advancements in technology and technique, along with comprehensive clinical trials, are essential to further define the role and optimize the use of these interventions.
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MDPI and ACS Style
Cavallino, C.; Franzino, M.; Abdirashid, M.; Maltese, L.; Bacci, E.; Rametta, F.; Ugo, F.
Novel Challenges and Therapeutic Options for Pulmonary Embolism and Deep Vein Thrombosis. J. Pers. Med. 2024, 14, 885.
https://doi.org/10.3390/jpm14080885
AMA Style
Cavallino C, Franzino M, Abdirashid M, Maltese L, Bacci E, Rametta F, Ugo F.
Novel Challenges and Therapeutic Options for Pulmonary Embolism and Deep Vein Thrombosis. Journal of Personalized Medicine. 2024; 14(8):885.
https://doi.org/10.3390/jpm14080885
Chicago/Turabian Style
Cavallino, Chiara, Marco Franzino, Mohamed Abdirashid, Ludovica Maltese, Elodi Bacci, Francesco Rametta, and Fabrizio Ugo.
2024. "Novel Challenges and Therapeutic Options for Pulmonary Embolism and Deep Vein Thrombosis" Journal of Personalized Medicine 14, no. 8: 885.
https://doi.org/10.3390/jpm14080885
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