Immune Response of Eastern Honeybee Worker to Nosema ceranae Infection Revealed by Transcriptomic Investigation
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Transcriptome Data Source
2.2. Confirmation of Effective Infection of Eastern Honeybee Workers by N. ceranae
2.3. Identification and Analysis of DEGs
2.4. GO Categorization and KEGG Pathway Enrichment Analysis of DEGs
2.5. Construction and Analysis of Immune-Associated Regulatory Network of DEGs
2.6. RT-qPCR Validation of DEGs
2.7. Statistical Analysis
3. Results
3.1. Effective Infection of A. c. cerana Worker by N. ceranae
3.2. DEGs Involved in A. c. cerana Workers’ Midgut Response to N. ceranae Infection
3.3. GO Terms and KEGG Pathways Enriched by Host DEGs
3.4. Host DEGs Relevant to Cellular and Humoral Immune Pathways
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Xing, W.; Zhou, D.; Long, Q.; Sun, M.; Guo, R.; Wang, L. Immune Response of Eastern Honeybee Worker to Nosema ceranae Infection Revealed by Transcriptomic Investigation. Insects 2021, 12, 728. https://doi.org/10.3390/insects12080728
Xing W, Zhou D, Long Q, Sun M, Guo R, Wang L. Immune Response of Eastern Honeybee Worker to Nosema ceranae Infection Revealed by Transcriptomic Investigation. Insects. 2021; 12(8):728. https://doi.org/10.3390/insects12080728
Chicago/Turabian StyleXing, Wenhao, Dingding Zhou, Qi Long, Minghui Sun, Rui Guo, and Limei Wang. 2021. "Immune Response of Eastern Honeybee Worker to Nosema ceranae Infection Revealed by Transcriptomic Investigation" Insects 12, no. 8: 728. https://doi.org/10.3390/insects12080728
APA StyleXing, W., Zhou, D., Long, Q., Sun, M., Guo, R., & Wang, L. (2021). Immune Response of Eastern Honeybee Worker to Nosema ceranae Infection Revealed by Transcriptomic Investigation. Insects, 12(8), 728. https://doi.org/10.3390/insects12080728