Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection
Abstract
:1. Introduction
2. Anti-HA Antibodies: A Brief Overview
3. MBCs and the Anti-HA Antibody Response to Influenza Infection
3.1. MBCs and Initial Antigen Encounter
3.2. MBC Activation and Early Anti-HA Antibody Production
3.3. MBCs and Anti-HA Stalk Antibody Production
3.4. MBCs and Imprinting of Antibody Responses to the HA Stalk
3.5. Extra-Germinal Center Generation of MBCs
3.6. Germinal Center Events
3.7. Regulation of the Anti-HA Response by MBC-Derived Antibodies
4. Summary
Author Contributions
Funding
Conflicts of Interest
References
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Sangster, M.Y.; Nguyen, P.Q.T.; Topham, D.J. Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection. Pathogens 2019, 8, 167. https://doi.org/10.3390/pathogens8040167
Sangster MY, Nguyen PQT, Topham DJ. Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection. Pathogens. 2019; 8(4):167. https://doi.org/10.3390/pathogens8040167
Chicago/Turabian StyleSangster, Mark Y., Phuong Q. T. Nguyen, and David J. Topham. 2019. "Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection" Pathogens 8, no. 4: 167. https://doi.org/10.3390/pathogens8040167