Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Animals and Housing
2.2. Diets and Feeding Concept
2.3. Experimental Procedure
2.4. Dissection
2.5. Sample Preparation and Analyses
2.6. Skatole and Indole Adsorption In Vitro
2.7. Statistical Analysis
3. Results and Discussions
3.1. Reduction in Skatole and Indole In Vitro
3.2. Performance Parameters
3.3. Reduction in Skatole and Indole In Vivo
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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Item | Percentage |
---|---|
Barley | 35.0 |
Wheat | 16.0 |
Soybean meal * | 15.0 |
Maize | 15.0 |
Waffle meal | 4.0 |
Wheat bran | 4.0 |
Beet pulp | 1.0 |
Sunflower extraction meal | 1.0 |
Fish protein concentrate | 1.0 |
Premix ** | 8.0 |
CON | PURE | COAT | ||
---|---|---|---|---|
Organic matter | g/kg DM | 947 | 947 | 946 |
Crude protein | 192 | 186 | 189 | |
Ether extract | 50.6 | 61.2 | 51.8 | |
Crude fibre | 52.4 | 55.7 | 53.3 | |
NfE 1 | 652 | 644 | 652 | |
Calcium | 7.17 | 7.55 | 7.75 | |
Phosphorus | 5.43 | 5.34 | 5.53 | |
Potassium | 7.22 | 7.10 | 7.09 | |
Magnesium | 2.16 | 2.12 | 2.16 | |
Copper | mg/kg DM | 51.5 | 49.5 | 51.2 |
Zinc | 153 | 164 | 152 | |
Iron | 409 | 455 | 406 |
Indole Reduction (%) | Skatole Reduction (%) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
PURE | COAT | FAT | PURE | COAT | FAT | |||||||
Colon chyme | 18.80 ± 4.22 | a 0.005 | 14.53 ± 0.73 | a 0.019 | 1.00 ± 0.00 | b | 17.57 ± 1.82 | a 0.007 (to b) | 9.17 ± 1.12 | b 0.008 (to c) | 1.00 ± 0.00 | c < 0.001 (to a) |
Caecum chyme | 24.40 ± 0.81 | a < 0.001 | 17.53 ± 3.20 | a 0.003 | 1.60 ± 0.60 | b | 22.10 ± 0.32 | a < 0.001 | 14.20 ± 3.31 | a 0.007 | 1.00 ± 0.00 | b |
Water | 90.03 ± 0.20 | a <0.001 | 19.80 ± 1.08 | b < 0.001 | 1.00 ± 0.00 | c < 0.001 | 99.73 ± 0.09 | a < 0.001 | 33.43 ± 2.97 | b < 0.001 | 1.00 ± 0.00 | c < 0.001 |
Colon Chyme | Caecum Chyme | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Indole (µg/g DM) | Skatole (µg/g DM) | Indole (µg/g DM) | Skatole (µg/g DM) | |||||||||
CON | PURE | COAT | CON | PURE | COAT | CON | PURE | COAT | CON | PURE | COAT | |
8.11 ± 0.69 a | 12.28 ± 1.28 a | 1.32 ± 0.00 a | 62.39 ± 3.83 a c | 21.51 ± 1.84 a | 1.32 ± 0.00 a | 41.30 ± 1.80 a | 15.65 ± 3.39 a | 27.86 ± 1.88 a | 13.83 ± 0.08 a | 2.04 ± 0.00 a | 2.91 ± 0.00 a | |
12.18 ± 0.95 a | 1.40 ± 0.00 b | 3.08 ± 0.41 a | 169.01 ± 11.61 b | 84.11 ± 9.40 b | 51.68 ± 4.53 b | 9.26 ± 1.19 b | 2.48 ± 0.00 b | 2.68 ± 0.49 b | 26.93 ± 6.27 a | 3.67 ± 0.60 a b | 2.30 ± 0.11 a | |
8.83 ± 0.25 a | 5.14 ± 1.02 b | 1.66 ± 0.00 a | 38.01 ± 1.45 a | 35.17 ± 2.66 a | 38.43 ± 0.49 c | 5.90 ± 1.11 b | 12.72 ± 0.87 a b | 2.38 ± 0.00 b | 2.27 ± 0.00 a | 2.04 ± 0.00 b | 2.63 ± 0.18 a | |
23.46 ± 3.32 b | 2.30 ± 0.58 b | 1.59 ± 0.00 a | 73.31 ± 5.08 c e | 85.28 ± 6.43 b | 46.72 ± 2.28 bc | 8.22 ± 0.50 b | 38.20 ± 1.90 c | 2.11 ± 0.00 b | 81.16 ± 5.84 b | 46.43 ± 3.47 c | 13.90 ± 2.40 b | |
24.12 ± 1.83 b | 27.57 ± 2.06 c | 1.55 ± 0.00 a | 4.18 ± 0.43 d | 69.02 ± 5.10 b | 20.57 ± 1.59 d | 23.93 ± 4.65 a b | 45.82 ± 4.92 c | 2.36 ± 0.14 b | 2.44 ± 0.00 a | 2.94 ± 0.00 a b | 2.22 ± 0.00 a | |
14.38 ± 1.41 a | 33.02 ± 1.98 c | 32.19 ± 3.31 b | 95.83 ± 6.82 e | 13.33 ± 0.80 a | 37.29 ± 2.11 c | 48.23 ± 5.30 a b | 11.17 ± 1.16 a b | 10.35 ± 1.27 c | 18.38 ± 2.34 a | 2.83 ± 0.37 a b | 2.59 ± 0.00 a | |
Mean | 15.18 ± 1.67 A | 13.62 ± 3.04 A | 6.90 ± 2.79 A | 73.79 ± 12.62 A | 51.40 ± 7.32 AB | 32.67 ± 4.21 B | 18.25 ± 3.62 AB | 21.01 ± 3.87 A | 7.96 ± 2.30 B | 22.48 ± 6.82 A | 9.99 ± 3.99 AB | 4.42 ± 1.08 B |
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Witte, F.; Pajic, A.; Menger, F.; Tomasevic, I.; Schubert, D.C.; Visscher, C.; Terjung, N. Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal. Animals 2021, 11, 2720. https://doi.org/10.3390/ani11092720
Witte F, Pajic A, Menger F, Tomasevic I, Schubert DC, Visscher C, Terjung N. Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal. Animals. 2021; 11(9):2720. https://doi.org/10.3390/ani11092720
Chicago/Turabian StyleWitte, Franziska, Aleksandar Pajic, Florian Menger, Igor Tomasevic, Dana Carina Schubert, Christian Visscher, and Nino Terjung. 2021. "Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal" Animals 11, no. 9: 2720. https://doi.org/10.3390/ani11092720
APA StyleWitte, F., Pajic, A., Menger, F., Tomasevic, I., Schubert, D. C., Visscher, C., & Terjung, N. (2021). Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal. Animals, 11(9), 2720. https://doi.org/10.3390/ani11092720