Tracheal Hemangioma Causing Lung Emphysema and Pneumopericardium in a Rabbit—A Case Report
, Eleonora Brambilla 3 and Valeria Grieco 3Round 1
Reviewer 1 Report
Dear author
This is a nice written Case report about rare described disease in animals
I had some problems to give my comments because there are no line number
Please see my comments
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Location / your text |
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Title |
Why you are not saying pneumopericardium in consequence of tracheal obstruction by an hemangioma, please see at the end an proposed title |
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End of introduction |
Same as above |
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Chapter 2 “exhibiting dyspnea” |
Is it possible to describe the type of dyspnoea |
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Chapter |
I am missing typically vital signs heart rat respiration rate temperature |
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Chapetr 2 |
Question: an x-ray was not done by privat vet or the clinic |
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Chapter 2 “meloxicam(Metacam” |
Please change to “meloxicam (Metacam” |
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Chapter 2 |
2Question Was there any stridor Did the rabbit had dyspnoea at this time point |
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Chapter 2 |
Cardiac auscultation is missing |
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Chapter 2 “mild monocytosis and leukopenia” |
Please give number and your laboratory reference |
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“b.w” |
You are not writing b.w at any medication ? |
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Ct technique |
Typically more details should be named like slice thickness time point of different runs depend to the contrast injection |
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CT description |
I am missing results of the extrathoracic trachea |
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Moderate emphysema |
Please describe your definition of moderate emphysema at the best with a reference Did you measure the density of the lung |
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CT description |
It is unclear which information is coming from native scan and which from contrast scan |
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after the test |
Is this 5 minutes after the contrast application (during anaesthesia) or 5 minutes after end of anaesthesia |
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“The internal ex-amination of the trachea revealed” |
Do you have a photo on this changes Was the lumen narrowed by the tumor and if so, how much |
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“In the lung, moderate edema” |
Please give a reference for your definition of moderate |
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End of chapter two |
Was a bacterial culture of the pericardium done ? |
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Chapter 3 |
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Emphysema / rabbit |
Please give a reference that tracheal obstruction is causing lung emphysema in humans? animals ? rabbits ? |
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In this process, the bronchial and peribronchial inflammatory reaction observed could have contributed to a more severe and extensive rupture of the alveolar walls with movement of air to the pericardial sac |
You should go with the same sentence to title and end of introduction For example “Tracheal hemangioma causing lung emphysema and pneumopericardium in a rabbit”
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Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Very interesting case report, well written and scientifically structured. Three minotr remarks:
Phrase: 'Due to the lack of improvement, the patient was referred again and, since during auscultation increased respiratory noises were found, the animal was submitted to a respiratory system computed tomography (CT) scan.'
Comment: Strange structure of the sentence, please rephrase.
Phrase: 'Before the CT, complete blood count and biochemical exams were performed revealing a mild monocytosis and leukopenia in the absence of other abnormalities.'
Comment: Please add values and normal values.
Phrase: 'After the rabbit’s death, the owners considered performing a necropsy, and the body was frozen. After the owners’ consent, the rabbit cadaver was defrosted, and a complete necropsy was performed.'
Comment: Please add how long the body was stored and if and how this could influence the post mortem exam and possibly histopathology.
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
