Mechanical Testing of the New Cage for Tibial Tuberosity Advancement with the Cranial Implant Fixation (TTA CF) Technique—Ex Vivo Study on Sheep Model
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Limb Preparation
2.2. Mechanical Testing
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
References
- Apelt, D.; Kowaleski, M.P.; Boudrieau, R.J. Effect of tibial tuberosity advancement on cranial tibial subluxation in canine cranial cruciate-deficient stifle joints: An in vitro experimental study. Vet. Surg. 2007, 36, 170–177. [Google Scholar] [CrossRef] [PubMed]
- Kipfer, N.M.; Tepic, S.; Damur, D.M.; Guerrero, T.; Hässig, M.; Montavon, P.M. Effect of tibial tuberosity advancement on femorotibial shear in cranial cruciate-deficient stifles: An in vitro study. Vet. Comp. Orthop. Traumatol. 2008, 21, 385–390. [Google Scholar]
- Bruce, W.J.; Rose, A.; Tuke, J.; Robins, G.M. Evaluation of the Triple Tibial Osteotomy. A new technique for the management of the canine cruciate-deficient stifle. Vet. Comp. Orthop. Traumatol. 2007, 20, 159–168. [Google Scholar]
- Slocum, B.; Slocum, T.D. Tibial plateau leveling osteotomy for repair of cranial cruciate ligament rupture in the canine. Vet. Clin. N. Am. Small Anim. Pract. 1993, 23, 777–795. [Google Scholar] [CrossRef]
- Tepic, S.; Damur, D.M.; Montavon, P.M. Biomechanics of the stifle joint. In Proceedings of the 1st World Orthopaedic Veterinary Congress, Munich, Germany, 5–8 September 2002; pp. 189–190. [Google Scholar]
- Montavon, P.M.; Damur, D.M.; Tepic, S. Advancement of the tibial tuberosity for the treatment of cranial cruciate deficient canine stifle. In Proceedings of the 1st World Orthopedic Veterinary Congress, Munich, Germany, 5–8 September 2002; p. 152. [Google Scholar]
- Etchepareborde, S.; Barthelemy, N.; Mills, J.; Pascon, F.; Ragetly, G.R.; Balligand, M. Mechanical testing of a modified stabilisation method for tibial tuberosity advancement. Vet. Comp. Orthop. Traumatol. 2010, 23, 400–405. [Google Scholar] [PubMed]
- Samoy, Y.; Verhoeven, G.; Bosmans, T.; van der Vekens, E.; de Bakker, E.; Verleyen, P.; van Ryssen, B. TTA Rapid. Description of the Technique and Short Term Clinical Trial Results of the First 50 Cases. Vet. Surg. 2015, 44, 474–484. [Google Scholar] [CrossRef] [PubMed]
- Zhalniarovich, Y.; Mieszkowska, M.; Przyborowska-Zhalniarovich, P.; Głodek, J.; Sobolewski, A.; Waluś, G.; Adamiak, Z. A novel tibial tuberosity advancement technique with cranial implant fixation (TTA CF): A pilot study in sheep. BMC Vet. Res. 2018, 14, 231. [Google Scholar] [CrossRef]
- Zhalniarovich, Y.; Sobolewski, A.; Waluś, G.; Adamiak, Z. Evaluation, description of the technique, and clinical outcomes after tibial tuberosity advancement with cranial fixation (TTA CF) for cranial cruciate ligament rupture in 22 dogs. Top. Companion Anim. Med. 2018, 33, 65–72. [Google Scholar] [CrossRef]
- Dennler, R.; Kipfer, N.M.; Tepic, S.; Hassig, M.; Montavon, P.M. Inclination of the patellar ligament in relation to flexion angle in stifle joints of dogs without degenerative joint disease. Am. J. Vet. Res. 2006, 67, 1849–1854. [Google Scholar] [CrossRef]
- Lafaver, S.; Miller, N.A.; Stubbs, W.P.; Taylor, R.A.; Boudrieau, R.J. Tibial tuberosity advancement for stabilization of the canine cranial cruciate ligament-deficient stifle joint: Surgical technique, early results, and complications in 101 dogs. Vet. Surg. 2007, 36, 573–586. [Google Scholar] [CrossRef]
- Maquet, P. Advancement of the tibial tuberosity. Clin. Orthop. Relat. Res. 1976, 115, 225–230. [Google Scholar] [CrossRef]
- Kyon Pharma, I. TTA-2; KYON Pharma, Inc.: Zurich, Switzerland, 2012; Available online: https://www.kyon.ch/wp-content/uploads/2020/04/Kyon_Catalog_2019_GzD.pdf (accessed on 1 May 2022).
- Meeson, R.L.; Corah, L.; Conroy, M.C.; Calvo, I. Relationship between tibial conformation, cage size and advancement achieved in TTA procedure. BMC Vet. Res. 2018, 20, 104. [Google Scholar] [CrossRef] [PubMed]
- Lins, B.T.; Rahal, S.C.; Louzada, M.J.; Dalmas, J.C.; Selmi, A.L. Mechanical resistance of the modified stabilization method for the tibial tuberosity advancement technique. Ex vivo experimental study in dogs. Ciência Rural 2009, 39, 467–472. [Google Scholar] [CrossRef]
- McCartney, W.; Ober, C.; Benito, M.; MacDonald, B. Comparison of tension band wiring and other tibial tuberosity advancement techniques for cranial cruciate ligament repair: An experimental study. Acta Vet. Scand. 2019, 61, 44. [Google Scholar] [CrossRef]
- Brunel, L.; Etchepareborde, S.; Barthelemy, N.; Farnir, F.; Balligand, M. Mechanical testing of a new osteotomy design for tibial tuberosity advancement using the Modified Maquet Technique. Vet. Comp. Orthop. Traumatol. 2013, 26, 47–53. [Google Scholar]
- Hoffman, D.E.; Kowaleski, M.P.; Johnson, K.A.; Evans, R.B.; Boudrieau, R.J. Ex vivo biomechanical evaluation of the canine cranial cruciate ligament-deficient stifle with varying angles of stifle joint flexion and axial loads after tibial tuberosity advancement. Vet. Surg. 2009, 40, 311–320. [Google Scholar] [CrossRef]
- Etchepareborde, S.; Barthelemy, N.; Brunel, L.; Claeys, S.; Balligand, M. Biomechanical testing of a β-tricalcium phosphate wedge for advancement of the tibial tuberosity. Vet. Comp. Orthop. Traumatol. 2014, 27, 14–19. [Google Scholar] [PubMed]
- Witsberger, T.H.; Villamil, J.A.; Schultz, L.G.; Hanh, A.W.; Cook, J.L. Prevalence of and risk factors for hip dysplasia and cranial cruciate ligament deficiency in dogs. J. Am. Vet. Med. Assoc. 2008, 232, 1818–1824. [Google Scholar] [CrossRef]
- Boudrieau, R.J. Tibial plateau leveling osteotomy or tibial tuberosity advancement? Vet. Surg. 2009, 38, 1–22. [Google Scholar] [CrossRef]
- Hoffmann, D.E.; Miller, J.M.; Ober, C.P.; Lanz, O.I.; Martin, R.A.; Shires, P.K. Tibial tuberosity advancement in 65 canine stifles. Vet. Comp. Orthop. Traumatol. 2006, 19, 219–227. [Google Scholar]
- Cadmus, J.; Palmer, R.H.; Duncan, C. The effect of preoperative planning method on recommended tibial tuberosity advancement cage size. Vet. Surg. 2014, 43, 995–1000. [Google Scholar] [CrossRef] [PubMed]
- Bush, M.A.; Bowlt, K.; Gines, J.A.; Owen, M.R. Effect of use of different landmark methods on determining stifle angle and on calculated tibial tuberosity advancement. Vet. Comp. Orthop. Traumatol. 2011, 24, 205–210. [Google Scholar] [PubMed]
- Wolf, R.E.; Scavelli, T.D.; Hoelzler, M.G.; Fulcher, R.P.; Bastian, R.P. Surgical and postoperative complications associated with tibial tuberosity advancement for cranial cruciate ligament rupture in dogs: 458 cases (2007–2009). J. Am. Vet. Med. Assoc. 2012, 240, 1481–1487. [Google Scholar] [CrossRef]
- Trisciuzzi, R.; Fracassi, L.; Martin, H.A.; Forleo, D.M.; Amat, D.; Santos-Ruiz, L.; de Palma, E.; Crovace, A.M. Forty-one cases of treatment of cranial cruciate ligament rupture with porous TTA: Three years of follow up. Vet. Sci. 2019, 6, 18. [Google Scholar] [CrossRef] [PubMed]
- Etchepareborde, S.; Mills, J.; Busoni, V.; Brunel, L.; Balligand, M. Theoretical discrepancy between cage size and efficient tibial tuberosity advancement in dogs treated for cranial cruciate ligament rupture. Vet. Comp. Orthop. Traumatol. 2011, 24, 27–31. [Google Scholar]
- Pape, D.; Madry, H. The preclinical sheep model of high tibial osteotomy relaxing basic science to the clinics: Standards, techniques and pitfalls. Knee Surg. Sports Traumatol. Arthrosc. 2013, 21, 228–236. [Google Scholar] [CrossRef]
- Pearse, A.I.; Richards, R.G.; Milz, S.; Schneider, E.; Pearce, S.G. Animal models for implant biomaterial research in bone: A review. Eur. Cells Mater. 2007, 13, 1–10. [Google Scholar] [CrossRef]
- Martini, L.; Fini, M.; Giavaresi, G.; Giardino, R. Sheep model in orthopedic research: A literature review. Comp. Med. 2001, 51, 292–299. [Google Scholar]
- Liebschner, M.A. Biomechanical considerations of animal models used in tissue engineering of bone. Biomaterials 2004, 25, 1697–1714. [Google Scholar] [CrossRef]
- Kitchen, H. Sheep as animal models in biomedical research. J. Am. Vet. Med. Assoc. 1977, 170, 615–619. [Google Scholar]
- McCalden, R.W.; McGeough, J.A.; Barker, M.B.; Courtbrown, C.M. Age-related changes in the tensile properties of cortical bone. The relative importance of changes in porosity, mineralization, and microstructure. J. Bone Jt. Surg. Am. 1993, 75, 1193–1205. [Google Scholar] [CrossRef] [PubMed]
- Goh, J.C.; Ang, E.J.; Bose, K. Effect of preservation medium on the mechanical properties of cat bones. Acta Orthop. Scand. 1989, 60, 465–467. [Google Scholar] [CrossRef] [PubMed]
- Linde, F.; Sorensen, H.C. The effect of different storage methods on the mechanical properties of trabecular bone. J. Biomech. 1993, 26, 1249–1252. [Google Scholar] [CrossRef]
Group 1 n = 5 | Group 2 n = 5 | |
---|---|---|
Median (IQR) | Median (IQR) | |
Displacement [mm] | 1.92 (1.64) | 1.4 (0.56) |
Maximal loaded forces [N] | 896 a (83) | 330 b (43) |
Displacement [mm] | 1.92 (1.64) | 1.4 (0.56) |
Work [J] | 0.84 a (0.02) | 0.22 b (0.11) |
Specimen Number | Maximal Forces to Pull Out the Cage [N] | Displacement at Maximal Load-to-Failure [mm] | Work [J] |
---|---|---|---|
Specimen 1.1 | 827 | 1.92 | 0.79 |
Specimen 1.2 | 896 | 1.87 | 0.84 |
Specimen 1.3 | 953 | 1.60 | 0.76 |
Specimen 1.4 | 910 | 4.31 | 1.96 |
Specimen 1.5 | 805 | 3.51 | 1.41 |
Mean | 878.2 | 2.64 | 1.15 |
Standard deviation | 61.04 | 1.20 | 0.52 |
Specimen Number | Maximal Forces to Pull Out the Cage [N] | Displacement at Maximal Load-to-Failure [mm] | Work [J] |
---|---|---|---|
Specimen 2.1 | 363 | 1.21 | 0.22 |
Specimen 2.2 | 330 | 0.97 | 0.16005 |
Specimen 2.3 | 320 | 1.77 | 0.2832 |
Specimen 2.4 | 393 | 5.72 | 1.12398 |
Specimen 2.5 | 246 | 1.40 | 0.1722 |
Mean | 330.4 | 2.21 | 0.39 |
Standard deviation | 55.26 | 1.98 | 0.41 |
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Zhalniarovich, Y.; Przyborowska-Zhalniarovich, P.; Tobolska, A.; Mieszkowska, M.; Abako, J.; Morawska-Kozłowska, M.; Mieszkowski, M.; Onichimowski, D. Mechanical Testing of the New Cage for Tibial Tuberosity Advancement with the Cranial Implant Fixation (TTA CF) Technique—Ex Vivo Study on Sheep Model. Animals 2022, 12, 2013. https://doi.org/10.3390/ani12162013
Zhalniarovich Y, Przyborowska-Zhalniarovich P, Tobolska A, Mieszkowska M, Abako J, Morawska-Kozłowska M, Mieszkowski M, Onichimowski D. Mechanical Testing of the New Cage for Tibial Tuberosity Advancement with the Cranial Implant Fixation (TTA CF) Technique—Ex Vivo Study on Sheep Model. Animals. 2022; 12(16):2013. https://doi.org/10.3390/ani12162013
Chicago/Turabian StyleZhalniarovich, Yauheni, Paulina Przyborowska-Zhalniarovich, Angelika Tobolska, Marta Mieszkowska, Justyna Abako, Magdalena Morawska-Kozłowska, Marcin Mieszkowski, and Dariusz Onichimowski. 2022. "Mechanical Testing of the New Cage for Tibial Tuberosity Advancement with the Cranial Implant Fixation (TTA CF) Technique—Ex Vivo Study on Sheep Model" Animals 12, no. 16: 2013. https://doi.org/10.3390/ani12162013