Next Article in Journal
Description of a Sarcoptic Mange Outbreak in Alpine Chamois Using an Enhanced Surveillance Approach
Previous Article in Journal
Ovine Neosporosis: The Current Global Situation
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Communication

Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan

Department of Animal Science, Graduate School of Environmental and Life Science, Okayama 700-8530, Japan
*
Author to whom correspondence should be addressed.
Animals 2022, 12(16), 2076; https://doi.org/10.3390/ani12162076
Submission received: 12 July 2022 / Revised: 11 August 2022 / Accepted: 12 August 2022 / Published: 15 August 2022
(This article belongs to the Section Animal System and Management)

Simple Summary

Reports presenting survey results for β-casein gene polymorphisms have increased, but none have been about Jersey cows in Asia. This study examined the CSN2 gene variants for 590 Jersey cows in Okayama Prefecture, located in the western region of Japan. Blood samples were collected at eight farms, and nucleotide substitutions were determined by sequencing exon 7 regions of chromosome 6 of the CSN2 gene. Blood biochemical analyses were also performed to clarify if A1A1, A1A2, and A2A2 cows differ in their metabolic profiles. The frequency of the A2 allele found in this study was numerically higher than those reported for Holsteins, crossbreeds, and Mexican and Danish Jerseys. The β-casein genotypes did not affect the metabolism of the major nutrients.

Abstract

This study aimed to investigate β-casein gene polymorphisms in Jersey cows in Japan. Blood samples were collected from 590 cows from eight Jersey farms in Okayama Prefecture, western Japan. Sequence analysis of exon 7 regions in chromosome 6 of the CSN2 gene revealed the genotype and allele frequencies of the β-casein variants. Considering that variant B belongs to the A1 group and variant I to the A2 group, plasma metabolite concentrations were compared among the A1A1, A1A2, and A2A2 group-based genotypes. The most frequent genotype was A2A2 (0.558), followed by A2B (0.190) and A2I (0.103). No variants of A3, F, G, H1, or H2 were found. The frequencies of group-based genotypes were A1A1 (0.032), A1A2 (0.303), and A2A2 (0.665). Although farm-to-farm differences were observed in the plasma concentrations of urea nitrogen, calcium, and phosphorus, no differences were found between the A1A1, A1A2, and A2A2 group-based genotypes; hence, the β-casein genotypes did not affect the metabolism of major nutrients. Owing to the high frequency of the A2 variant, Jersey cows can be considered an attractive breed for marker-assisted selection to create A2A2 herds.
Keywords: A2 milk; β-casein; Jersey; plasma metabolites; polymorphism A2 milk; β-casein; Jersey; plasma metabolites; polymorphism

Share and Cite

MDPI and ACS Style

Nuomin; Nguyen, Q.D.; Aodaohu; Nishino, N. Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan. Animals 2022, 12, 2076. https://doi.org/10.3390/ani12162076

AMA Style

Nuomin, Nguyen QD, Aodaohu, Nishino N. Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan. Animals. 2022; 12(16):2076. https://doi.org/10.3390/ani12162076

Chicago/Turabian Style

Nuomin, Qui Dang Nguyen, Aodaohu, and Naoki Nishino. 2022. "Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan" Animals 12, no. 16: 2076. https://doi.org/10.3390/ani12162076

APA Style

Nuomin, Nguyen, Q. D., Aodaohu, & Nishino, N. (2022). Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan. Animals, 12(16), 2076. https://doi.org/10.3390/ani12162076

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop