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Article

Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa

by
Phillipa Hay
1,2,*,†,
Mohammed Mohsin
1,3,*,†,
Liquan Liu
4,5,
Stephen Touyz
6,
Caroline Meyer
7,
Jon Arcelus
8,9,
Sloane Madden
10,
Evelyn Attia
11,
Kathleen M. Pike
12 and
Janet Conti
2,4
1
Mental Health Research Unit, Liverpool Hospital, South Western Sydney Local Health District, NSW Health, Liverpool, NSW 2170, Australia
2
Translational Health Research Institute, School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia
3
Faculty of Medicine & Health, School of Clinical Medicine, University of New South Wales, Sydney, NSW 2052, Australia
4
School of Psychology, Western Sydney University, Sydney, NSW 2560, Australia
5
The MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Sydney, NSW 2560, Australia
6
Inside Out Institute, University of Sydney, Sydney, NSW 2006, Australia
7
International Digital Laboratory, The University of Warwick, Coventry CV4 7AL, UK
8
Institute of Mental Health, University of Nottingham, Nottingham NG7 2TU, UK
9
Psychoneurobiology of Eating and Addictive Behaviors Group, Bellvitge Biomedical Research Institute (IDIBELL), Bellvitge University Hospital, University of Barcelona, 08908 Barcelona, Spain
10
The Sydney Children’s Hospitals Network, Westmead, Sydney, NSW 2145, Australia
11
The New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
12
World Health Organization Collaborating Centre for Capacity Building and Training in Global Mental Health, Columbia University Medical Center, New York, NY 10032, USA
 
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*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Behav. Sci. 2023, 13(8), 651; https://doi.org/10.3390/bs13080651
Submission received: 25 May 2023 / Revised: 28 July 2023 / Accepted: 1 August 2023 / Published: 3 August 2023
Review Reports Versions Notes

Abstract

Anorexia nervosa (AN) is a mental health disorder that has serious physical, emotional and social consequences. Whilst cognitive behavioural therapy for AN (CBT-AN) has demonstrated efficacy, there remains a global need to improve AN treatment. Compulsive exercise activity therapy (LEAP) is an active therapy consisting of the addition to CBT-AN of eight specific sessions that focus on exercise and motivation for behavioural change. This paper presents a secondary analysis of 74 female participants in a randomised control trial of LEAP plus CBT-AN versus CBT-AN alone. The main aim of this study was to explore putative predictors and to estimate the magnitude of changes due to LEAP for specific outcome measures. Participants (LEAP: n = 36; CBT-AN: n = 38) were assessed at three successive surveys: baseline, end of therapy, and 6 months post-therapy. The overall effect sizes for changes between baseline to end of therapy and baseline to 6-month follow-up assessment showed large effect sizes (Cohen’s d > = 0.80) for mental-health-related quality of life (MHRQoL), weight concern, dietary restraint, eating concern, AN stage change, and psychological distress (all p < 0.05). The results also indicated that several pre-treatment characteristics, including body mass index (BMI), level of eating disorder (ED) symptoms, and MHRQoL are important for identifying whether a treatment is likely to be effective. Future treatment programs should aim to optimise early improvements in BMI, ED symptoms, and MHRQoL.
Keywords: anorexia nervosa; eating disorder; mental health; quality of life; compulsive exercise activity therapy (LEAP) anorexia nervosa; eating disorder; mental health; quality of life; compulsive exercise activity therapy (LEAP)

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MDPI and ACS Style

Hay, P.; Mohsin, M.; Liu, L.; Touyz, S.; Meyer, C.; Arcelus, J.; Madden, S.; Attia, E.; Pike, K.M.; Conti, J. Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa. Behav. Sci. 2023, 13, 651. https://doi.org/10.3390/bs13080651

AMA Style

Hay P, Mohsin M, Liu L, Touyz S, Meyer C, Arcelus J, Madden S, Attia E, Pike KM, Conti J. Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa. Behavioral Sciences. 2023; 13(8):651. https://doi.org/10.3390/bs13080651

Chicago/Turabian Style

Hay, Phillipa, Mohammed Mohsin, Liquan Liu, Stephen Touyz, Caroline Meyer, Jon Arcelus, Sloane Madden, Evelyn Attia, Kathleen M. Pike, and Janet Conti. 2023. "Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa" Behavioral Sciences 13, no. 8: 651. https://doi.org/10.3390/bs13080651

APA Style

Hay, P., Mohsin, M., Liu, L., Touyz, S., Meyer, C., Arcelus, J., Madden, S., Attia, E., Pike, K. M., & Conti, J. (2023). Impact of LEAP and CBT-AN Therapy on Improving Outcomes in Women with Anorexia Nervosa. Behavioral Sciences, 13(8), 651. https://doi.org/10.3390/bs13080651

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