Suicidal Behaviors Among Medical Students: A Scoping Review of Systematic Reviews and Meta-Analyses
Abstract
1. Introduction
2. Methodology
2.1. Study Design
2.2. Identifying the Research Questions
2.3. Identifying Relevant Studies
2.4. Selecting Articles
2.5. Charting Data
2.6. Collating, Summarizing, and Reporting Results
3. Results
3.1. Prevalence of Suicidal Ideation Among Medical Students
3.2. Prevalence of Suicidal Attempt Among Medical Students
3.3. Risk Factors for Suicidal Ideation
3.4. Risk Factors for Suicidal Attempts
3.5. Non-Significant Associated Factors for Suicidal Ideation and Attempts
3.6. Recommendations for Future Research and Interventions
4. Discussion
4.1. Before vs. After COVID-19 Pandemic Era
4.2. Progression of Suicidal Ideation over Time
4.3. Prevalence of Suicidal Behavior Compared to University Students
4.4. Gender Differences in Suicidal Ideation and Attempts
4.5. Potential Risk Factors Not Explored
4.6. Future Research Directions
4.7. Limitations
4.8. Implications for Policy and Practice
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Agyapong, B., Shalaby, R., Vuong, W., Gusnowski, A., Surood, S., Greenshaw, A. J., Wei, Y., & Agyapong, V. I. O. (2023). Text4Hope effectiveness in reducing psychological symptoms among young adults in Canada: Longitudinal and naturalistic controlled program evaluation. Journal of Clinical Medicine, 12(5), 1942. [Google Scholar] [CrossRef]
- Agyapong, V. I. O., Shalaby, R., Hrabok, M., Vuong, W., Noble, J. M., Gusnowski, A., Mrklas, K., Li, D., Snaterse, M., Surood, S., Cao, B., Li, X. M., Greiner, R., & Greenshaw, A. J. (2021). Mental health outreach via supportive text messages during the COVID-19 pandemic: Improved mental health and reduced suicidal ideation after six weeks in subscribers of Text4Hope compared to a control population. International Journal of Environmental Research and Public Health, 18(4), 2157. [Google Scholar] [CrossRef]
- Agyapong-Opoku, G., Agyapong, B., Obuobi-Donkor, G., & Eboreime, E. (2023). Depression and anxiety among undergraduate health science students: A scoping review of the literature. Behavioral Sciences, 13(12), 1002. [Google Scholar] [CrossRef] [PubMed]
- Al-Najdi, S., Mansoor, A., Al Hayk, O., Al-Hashimi, N., Ali, K., & Daud, A. (2025). Silent struggles: A qualitative study exploring mental health challenges of undergraduate healthcare students. BMC Medical Education, 25(1), 157. [Google Scholar] [CrossRef] [PubMed]
- Angelakis, I., Gillespie, E. L., & Panagioti, M. (2019). Childhood maltreatment and adult suicidality: A comprehensive systematic review with meta-analysis. Psychological Medicine, 49(7), 1057–1078. [Google Scholar] [CrossRef]
- Arksey, H., & O’Malley, L. (2005). Scoping studies: Towards a methodological framework. International Journal of Social Research Methodology, 8(1), 19–32. [Google Scholar] [CrossRef]
- Bentley, K. H., Franklin, J. C., Ribeiro, J. D., Kleiman, E. M., Fox, K. R., & Nock, M. K. (2016). Anxiety and its disorders as risk factors for suicidal thoughts and behaviors: A meta-analytic review. Clinical Psychology Review, 43, 30–46. [Google Scholar] [CrossRef]
- Canetto, S. S., & Sakinofsky, I. (1998). The gender paradox in suicide. Suicide and Life-Threatening Behavior, 28(1), 1–23. [Google Scholar] [CrossRef]
- Carrasco-Barrios, M. T., Huertas, P., Martín, P., Martín, C., Castillejos, M. C., Petkari, E., & Moreno-Küstner, B. (2020). Determinants of suicidality in the European general population: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 17(11), 4115. [Google Scholar] [CrossRef]
- Chen, C., Feng, R. L., Wang, J., Li, J., Liu, C., Hu, J., & Liu, L. C. (2023). Patients with cardiovascular disorders and suicidality: A systematic review and meta-analysis. Asian Journal of Psychiatry, 90, 103799. [Google Scholar] [CrossRef] [PubMed]
- Chew-Graham, C. A., Rogers, A., & Yassin, N. (2003). ‘I wouldn’t want it on my CV or their records’: Medical students’ experiences of help-seeking for mental health problems. Medical Education, 37(10), 873–880. [Google Scholar] [CrossRef]
- Coentre, R., & Góis, C. (2018). Suicidal ideation in medical students: Recent insights. Advances in Medical Education and Practice, 9, 873–880. [Google Scholar] [CrossRef]
- Coentre, R. M., & Figueira, M. L. (2015). Depression and suicidal behavior in medical students: A systematic review. Current Psychiatry Reviews, 11(2), 86–101. [Google Scholar] [CrossRef]
- Darvishi, N., Farhadi, M., Haghtalab, T., & Poorolajal, J. (2015). Alcohol-related risk of suicidal ideation, suicide attempt, and completed suicide: A meta-analysis. PLoS ONE, 10(5), e0126870. [Google Scholar] [CrossRef] [PubMed]
- Du, W., Jia, Y. J., Hu, F. H., Ge, M. W., Cheng, Y. J., Qu, X., & Chen, H. L. (2023). Prevalence of suicidal ideation and correlated risk factors during the COVID-19 pandemic: A meta-analysis of 113 studies from 31 countries. Journal of Psychiatric Research, 166, 147–168. [Google Scholar] [CrossRef] [PubMed]
- Dutheil, F., Aubert, C., Pereira, B., Dambrun, M., Moustafa, F., Mermillod, M., Baker, J. S., Trousselard, M., Lesage, F. X., & Navel, V. (2019). Suicide among physicians and health-care workers: A systematic review and meta-analysis. PLoS ONE, 14(12), e0226361. [Google Scholar] [CrossRef]
- Dyrbye, L. N., Thomas, M. R., & Shanafelt, T. D. (2005). Medical student distress: Causes, consequences, and proposed solutions. Mayo Clinic Proceedings, 80(12), 1613–1622. [Google Scholar] [CrossRef]
- Dyrbye, L. N., Thomas, M. R., & Shanafelt, T. D. (2006). Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Academic Medicine, 81(4), 354–373. [Google Scholar] [CrossRef]
- Elamoshy, R., Bird, Y., Thorpe, L., & Moraros, J. (2018). Risk of depression and suicidality among diabetic patients: A systematic review and meta-analysis. Journal of Clinical Medicine, 7(11), 445. [Google Scholar] [CrossRef]
- Farooq, S., Tunmore, J., Wajid Ali, M., & Ayub, M. (2021). Suicide, self-harm and suicidal ideation during COVID-19: A systematic review. Psychiatry Research, 306, 114228. [Google Scholar] [CrossRef]
- García-Ramírez, G., Shamblen, S. R., Kaner, E., & Moore, R. S. (2025). The interaction between alcohol misuse and belongingness on suicidal ideation among military personnel. International Journal of Environmental Research and Public Health, 22(2), 246. [Google Scholar] [CrossRef]
- Guille, C., Zhao, Z., Krystal, J., Nichols, B., Brady, K., & Sen, S. (2015). Web-based cognitive behavioral therapy intervention for the prevention of suicidal ideation in medical interns: A randomized clinical trial. JAMA Psychiatry, 72(12), 1192–1198. [Google Scholar] [CrossRef] [PubMed]
- Han, B., Crosby, A. E., Ortega, L. A., Parks, S. E., Compton, W. M., & Gfroerer, J. (2016). Suicidal ideation, suicide attempt, and occupations among employed adults aged 18–64 years in the United States. Comprehensive Psychiatry, 66, 176–186. [Google Scholar] [CrossRef] [PubMed]
- Harmer, B., Lee, S., Rizvi, A., & Saadabadi, A. (2025). Suicidal ideation. In StatPearls. StatPearls Publishing Copyright © 2025. StatPearls Publishing LLC. [Google Scholar]
- Harris, L. M., Huang, X., Linthicum, K. P., Bryen, C. P., & Ribeiro, J. D. (2020). Sleep disturbances as risk factors for suicidal thoughts and behaviours: A meta-analysis of longitudinal studies. Scientific Reports, 10(1), 13888. [Google Scholar] [CrossRef] [PubMed]
- Höller, I., & Forkmann, T. (2022). Ambivalent heroism?—Psychological burden and suicidal ideation among nurses during the COVID-19 pandemic. Nursing Open, 9(1), 785–800. [Google Scholar] [CrossRef]
- Ikhsan, D., Prananjaya, B., Aini, S., Suryani, P., Cendana, V., & Pang, N. (2022). Suicide in medical student: How to prevent? Jurnal Psikiatri Surabaya, 11, 54–60. [Google Scholar] [CrossRef]
- Ishak, W., Nikravesh, R., Lederer, S., Perry, R., Ogunyemi, D., & Bernstein, C. (2013). Burnout in medical students: A systematic review. The Clinical Teacher, 10(4), 242–245. [Google Scholar] [CrossRef]
- Jovanović, N., Beezhold, J., Tateno, M., Barrett, E., Vlachos, I., Fiorillo, A., Hanon, C., Kazakova, O., Nawka, A., Wuyts, P., Wong, V., Papp, S., Rujević, J., Racetovic, G., Mihai, A., Marques, J. G., Malik, A., Weiss, U., Rolko, T., … Podlesek, A. (2019). Depression and suicidality among psychiatric residents—Results from a multi-country study. Journal of Affective Disorders, 249, 192–198. [Google Scholar] [CrossRef]
- Kabir, H., Chowdhury, S. R., Roy, A. K., Chowdhury, S. A., Islam, M. N., Chomon, R. J., Akter, M., & Hossain, A. (2023). Association of workplace bullying and burnout with nurses’ suicidal ideation in Bangladesh. Scientific Reports, 13(1), 14641. [Google Scholar] [CrossRef]
- Kaggwa, M. M., Najjuka, S. M., Favina, A., Griffiths, M. D., & Mamun, M. A. (2023). Suicidal behaviors and associated factors among medical students in Africa: A systematic review and meta-analysis. Journal of Affective Disorders Reports, 11, 100456. [Google Scholar] [CrossRef]
- Kaur, H., Gupta, V., Garg, A., & Padhi, B. K. (2024). Prevalence of depression, anxiety, stress and suicide ideation among undergraduate Medical students in India: A systematic review and meta-analysis. National Journal of Community Medicine, 15(10), 868–883. [Google Scholar] [CrossRef]
- Kim, A. M., Jeon, S. W., Cho, S. J., Shin, Y. C., & Park, J. H. (2021). Comparison of the factors for suicidal ideation and suicide attempt: A comprehensive examination of stress, view of life, mental health, and alcohol use. Asian Journal of Psychiatry, 65, 102844. [Google Scholar] [CrossRef]
- Mata, D. A., Ramos, M. A., Bansal, N., Khan, R., Guille, C., Di Angelantonio, E., & Sen, S. (2015). Prevalence of depression and depressive symptoms among resident physicians: A systematic review and meta-analysis. JAMA, 314(22), 2373–2383. [Google Scholar] [CrossRef] [PubMed]
- Mateen, A., Kumar, V., Singh, A. K., Yadav, B., Mahto, M., & Mahato, S. (2024). Suicide and Suicidal Ideation in Medical Students: A Systematic Review. Cureus, 16(7), e65246. [Google Scholar] [CrossRef] [PubMed]
- Meireles Campos, V., & Aleluia, I. (2019). Indicators of suicide ideation among medical students: A systematic review. International Journal of Education and Health, 3(1), 78–91. [Google Scholar] [CrossRef]
- Menon, N. K., Shanafelt, T. D., Sinsky, C. A., Linzer, M., Carlasare, L., Brady, K. J. S., Stillman, M. J., & Trockel, M. T. (2020). Association of physician burnout with suicidal ideation and medical errors. JAMA Network Open, 3(12), e2028780. [Google Scholar] [CrossRef]
- Molina, N., Viola, M., Rogers, M., Ouyang, D., Gang, J., Derry, H., & Prigerson, H. G. (2019). Suicidal ideation in bereavement: A systematic review. Behavioral Sciences, 9(5), 53. [Google Scholar] [CrossRef]
- Mortier, P., Cuijpers, P., Kiekens, G., Auerbach, R. P., Demyttenaere, K., Green, J. G., Kessler, R. C., Nock, M. K., & Bruffaerts, R. (2018). The prevalence of suicidal thoughts and behaviours among college students: A meta-analysis. Psychological Medicine, 48(4), 554–565. [Google Scholar] [CrossRef]
- Mudiyanselage, S. P. K., Tsai, Y.-T., Dilhani, M. S., Tsai, Y.-J., Yang, Y.-H., Lu, Z.-T., & Ko, N.-Y. (2024). Global overview of suicidal behavior and risk factors among general population during the COVID-19 pandemic: A Systematic review and a meta-regression. Psychiatric Quarterly, 96(2), 381–444. [Google Scholar] [CrossRef]
- Oh, D. J., Shin, Y. C., Oh, K. S., Shin, D. W., Jeon, S. W., & Cho, S. J. (2023). Examining the links between burnout and suicidal ideation in diverse occupations. Frontiers in Public Health, 11, 1243920. [Google Scholar] [CrossRef]
- Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. [Google Scholar] [CrossRef]
- Peng, P., Hao, Y., Liu, Y., Chen, S., Wang, Y., Yang, Q., Wang, X., Li, M., He, L., Wang, Q., Ma, Y., He, H., Zhou, Y., Wu, Q., & Liu, T. (2023). The prevalence and risk factors of mental problems in medical students during COVID-19 pandemic: A systematic review and meta-analysis. Journal of Affective Disorders, 321, 167–181. [Google Scholar] [CrossRef]
- Pigeon, W. R., Pinquart, M., & Conner, K. (2012). Meta-analysis of sleep disturbance and suicidal thoughts and behaviors. The Journal of Clinical Psychiatry, 73(9), e1160–e1167. [Google Scholar] [CrossRef]
- Pirkis, J., Gunnell, D., Shin, S., Del Pozo-Banos, M., Arya, V., Aguilar, P. A., Appleby, L., Arafat, S. M. Y., Arensman, E., Ayuso-Mateos, J. L., Balhara, Y. P. S., Bantjes, J., Baran, A., Behera, C., Bertolote, J., Borges, G., Bray, M., Brečić, P., Caine, E., … Spittal, M. J. (2022). Suicide numbers during the first 9–15 months of the COVID-19 pandemic compared with pre-existing trends: An interrupted time series analysis in 33 countries. EClinicalMedicine, 51, 101573. [Google Scholar] [CrossRef]
- Poorolajal, J., & Darvishi, N. (2016). Smoking and suicide: A meta-analysis. PLoS ONE, 11(7), e0156348. [Google Scholar] [CrossRef] [PubMed]
- Rahman, M., Kabir, M. H. M. I., Sultana, S., Abdullah, I., & Shimu, A. T. (2025). Suicidal behaviours and associated factors among Bangladeshi medical students: A systematic review and meta-analysis (2000–2024). BMJ Open, 15(3), e095573. [Google Scholar] [CrossRef] [PubMed]
- Ribeiro, J. D., Huang, X., Fox, K. R., & Franklin, J. C. (2018). Depression and hopelessness as risk factors for suicide ideation, attempts and death: Meta-analysis of longitudinal studies. The British Journal of Psychiatry, 212(5), 279–286. [Google Scholar] [CrossRef] [PubMed]
- Riera-Serra, P., Navarra-Ventura, G., Castro, A., Gili, M., Salazar-Cedillo, A., Ricci-Cabello, I., Roldán-Espínola, L., Coronado-Simsic, V., García-Toro, M., Gómez-Juanes, R., & Roca, M. (2024). Clinical predictors of suicidal ideation, suicide attempts and suicide death in depressive disorder: A systematic review and meta-analysis. European Archives of Psychiatry and Clinical Neuroscience, 274(7), 1543–1563. [Google Scholar] [CrossRef]
- Rotenstein, L. S., Ramos, M. A., Torre, M., Bradley Segal, J., Peluso, M. J., Guille, C., Sen, S., & Mata, D. A. (2016). Prevalence of depression, depressive symptoms, and suicidal ideation among medical students a systematic review and meta-analysis. JAMA-Journal of the American Medical Association, 316(21), 2214–2236. [Google Scholar] [CrossRef]
- Ryan, E., Hore, K., Power, J., & Jackson, T. (2023). The relationship between physician burnout and depression, anxiety, suicidality and substance abuse: A mixed methods systematic review. Frontiers in Public Health, 11, 1133484. [Google Scholar] [CrossRef]
- Seo, C., Di Carlo, C., Dong, S. X., Fournier, K., & Haykal, K.-A. (2021). Risk factors for suicidal ideation and suicide attempt among medical students: A meta-analysis. PLoS ONE, 16(12), e0261785. [Google Scholar] [CrossRef] [PubMed]
- Sharif, S., & Akhtar, D. (2018). Relationship of Late Adolescent’s Attachment Styles with Suicidal Ideation and Resilience. Foundation University Journal of Psychology, 2, 96–120. [Google Scholar] [CrossRef]
- Sun, G., Zhao, J., Tian, S., Zhang, L., & Jia, C. (2020). Psychological strain and suicidal ideation in athletes: The multiple mediating effects of hopelessness and depression. International Journal of Environmental Research and Public Health, 17(21), 8087. [Google Scholar] [CrossRef] [PubMed]
- Thompson, D., Goebert, D., & Takeshita, J. (2010). A program for reducing depressive symptoms and suicidal ideation in medical students. Academic Medicine, 85(10), 1635–1639. [Google Scholar] [CrossRef]
- Tricco, A. C., Lillie, E., Zarin, W., O’Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowan, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garritty, C., … Straus, S. E. (2018). PRISMA extension for Scoping Reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467–473. [Google Scholar] [CrossRef]
- Tsegay, L., Abraha, M., & Ayano, G. (2020). The global prevalence of suicidal attempt among medical students: A systematic review and meta-analysis. Psychiatric Quarterly, 91(4), 1089–1101. [Google Scholar] [CrossRef]
- Van Niekerk, L., Scribante, L., & Raubenheimer, P. J. (2012). Suicidal ideation and attempt among South African medical students. South African Medical Journal, 102(6 Pt 2), 372–373. [Google Scholar] [CrossRef]
- Varshney, K., Patel, H., & Panhwar, M. A. (2024). Risks and Warning Signs for Medical Student Suicide Mortality: A Systematic Review. Archives of Suicide Research, 28(4), 1058–1076. [Google Scholar] [CrossRef]
- Wang, J., Liu, M., Bai, J., Chen, Y., Xia, J., Liang, B., Wei, R., Lin, J., Wu, J., & Xiong, P. (2023). Prevalence of common mental disorders among medical students in China: A systematic review and meta-analysis. Frontiers in Public Health, 11, 1116616. [Google Scholar] [CrossRef]
- World Health Organization. (2014). Preventing suicide: A global imperative. World Health Organization. [Google Scholar]
- World Health Organization. (2016). World Health Statistics 2016 [OP]: Monitoring health for the sustainable development goals (SDGs). World Health Organization. [Google Scholar]
- World Health Organization. (2025). Suicide. World Health Organization. [Google Scholar]
- Xiong, F., Wang, L., Shen, L., Guo, W., Li, S., & Guan, Q. (2020). The relationship between multimorbidity and suicidal ideation: A meta-analysis. Journal of Psychosomatic Research, 138, 110257. [Google Scholar] [CrossRef]
- Xu, K., Hu, D., Liu, Y., Han, Y., Guo, X., Teng, F., & Zhou, Y. (2019). Relationship of suicidal ideation with demoralization, depression, and anxiety: A study of cancer patients in mainland China. Journal of Nervous & Mental Disease, 207(5), 326–332. [Google Scholar] [CrossRef]
- Yan, Y., Hou, J., Li, Q., & Yu, N. X. (2023). Suicide before and during the COVID-19 pandemic: A systematic review with meta-analysis. International Journal of Environmental Research and Public Health, 20(4), 3346. [Google Scholar] [CrossRef]
- Zeng, W., Chen, R., Wang, X., Zhang, Q., & Deng, W. (2019). Prevalence of mental health problems among medical students in China: A meta-analysis. Medicine, 98(18), e15337. [Google Scholar] [CrossRef]
- Zhang, J., Liu, Y., Zhang, J., & Chen, C. (2018). Linking psychological strain and suicide ideation: A test of the mediating effect of self-determination among Chinese workers. The Journal of Nervous and Mental Disease, 206(5), 362–369. [Google Scholar] [CrossRef]
Author/Date | Time Period | Number of Included Articles; Review Type | Continent of Study Population | Aim of Review | Participant Characteristics and Sample Size | Bias Assessment | Associated Factors Identified | Factors Not Significantly Associated | Key Findings on Prevalence | Other Significant Findings | Recommendations |
---|---|---|---|---|---|---|---|---|---|---|---|
(R. Coentre & Góis, 2018) | July 2011–May 2018. | 17; Systematic review. | Europe (n = 3), North America (n = 2), Asia (n = 9), Africa (n = 2), South America (n = 1). | To gather recent knowledge about suicidal ideation in medical students in both Western and non-Western countries. | 13,244 medical students. | None. | Depression and depressive symptoms, previous diagnosis of a psychiatric disorder, lower socioeconomic status/financial difficulties, having a history of drug use, and feeling neglected by parents were frequently associated with suicidal ideation. | - | Over the past 12 months prevalences ranged from 7% to 35.6% during medical school time from 3.7% to 4.7% current suicidal ideation ranged from 1.8% to 24.6% lifetime from 2.9% to 53.6% | There is some trend in the recent findings suggesting that females are more at risk of suicidal ideation among medical students. | Future research should look at preventive and treatment programs to reduce suicidal ideation in medical students, as well as the influence of medical school culture on suicidal ideation. |
(R. M. Coentre & Figueira, 2015) | January 2005–June 2011. | 10 of a total 37 addressed suicidal behavior; systematic review. | Europe (n = 3), North America (n = 5), Asia (n = 1), South America (n = 1). | To systematically review articles related to depression and suicidal behavior among medical students. | 31,382 medical students among the ten studies. | None. | Not a primary focus. | - | Suicidal ideation in medical students ranged from 4.4% to 23.1%, with timeframes varying greatly between studies. | No significant relationship was found between suicidal behavior and age, or suicidal ideation and race. | Future studies should evaluate variables with standardized interviews to reduce the likelihood of under-reporting associated with questionnaires. Preventative programs such as lectures promoting general well-being should be available for medical students. |
(Kaggwa et al., 2023) | Up until January 2022. | 14; systematic review and meta-analysis. | Africa (n = 14). | To determine the prevalence of suicidal behaviors (suicidal ideation, plan, attempt, and/or suicide) among medical students in Africa. | 8585 medical students. | There was publication bias based on visual inspection of the funnel plot for all three prevalences. | The factor of poor mental health, including depression, was associated with suicidal ideation and attempts in most studies. Use of addictive substances and anxiety were associated with only suicidal ideation in many of the studies The meta-analysis showed that the female gender (OR = 1.51, I2 = 19.72%), use of alcohol (OR = 2.70, I2 = 29.24%), depression (OR = 6.93, I2 =< 0.01%), and use of khat (OR = 2.40, I2 =< 0.01%) were significantly associated with having suicidal ideation and that depression (OR = 7.16, I2 =< 0.01%) was associated with suicide attempts. | The meta-analysis showed that family history of mental health disorders was not associated with suicidal ideation. The female gender, alcohol use and khat use were not associated with suicidal attempts. | The pooled prevalence of lifetime suicidal behaviors was 18.7% (I2 = 94.37%) for suicidal ideation, 3.8% (I2 = 0.03%) for suicidal plans, and 5.5% (I2 = 89.47%) for suicide attempts. | The female gender was not significantly associated with suicidal attempts in the meta-analysis. | Future research should use qualitative methods to understand the root causes of suicidal behaviors among medical students. This would allow for preventative techniques to be designed. |
(Kaur et al., 2024) | January 2000–June 2023. | 5 of a total of 43 studies addressed suicidal behavior; Systematic review and meta-analysis. | Asia (n = 5). | To provide a recent comprehensive insight into the prevalence of depression, stress, anxiety, and suicidal ideation among Indian undergraduate medical students. | 1611 medical students. | No evidence of publication bias, based on the funnel plots and Egger’s regression analyses | Not a primary focus. | - | The pooled prevalence of suicidal ideation was 21% (I2 = 98%). The prevalence varied from 9% to 54%. | Analysis from the data of two studies revealed that more female students (Pooled prevalence: 34%) were affected by suicidal ideation than male students (Pooled prevalence 26%). | Institutes should implement long-term policy programs to target the root of students’ mental health issues. Additionally, counseling services should be available for all students in medical colleges. |
(Mateen et al., 2024) | 2015–2023. | 8 of a total of 11 studies addressed suicidal behaviors; systematic reviews. | Asia (n = 7), Africa (n = 1). | To explore the causes of suicide and to mitigate psychiatric morbidity among medical students. | 2454 medical students. | None. | Stressors of suicidal ideation included academic pressure, personal relationship challenges, and professional expectations. | - | Not explicitly stated. | Evidence from four studies suggests that female suicidal ideation is more prevalent than that of males. Medical students experience higher rates of suicide and suicidal ideation compared to the general population. | Development and evaluation of interventions to reduce educational stress and increase psychological well-being in medical schools should be a focus of future research. |
(Peng et al., 2023) | 1 January 2020–1 April 2022. | 13 of a total of 201 studies addressed suicidal behaviors; systematic review and meta-analysis. | Not explicitly stated. | To evaluate the global prevalence and risk factors of several mental problems among medical students during the COVID-19 pandemic. | 26,708 medical students. | Egger’s test indicated that there was no publication bias in suicidal ideation. | Risk factors described are not specific to suicidal ideation. | - | The pooled prevalence of suicidal ideation was 15% (I2 = 98.7%). | The prevalence of suicidal ideation among medical students was found to be higher than before the COVID-19 pandemic. | There is a need for timely mental screening and intervention for medical students. The revealed risk factors should be used to identify high-risk subgroups of medical students and provide targeted interventions. |
(Rahman et al., 2025) | 1 January 2000–May 2024. | 6; systematic review and meta-analysis. | Asia (n = 6) | To determine the prevalence of suicidal behaviors and associated factors among medical students of Bangladesh. | 1625 medical students. | Egger’s test indicated significant publication bias. | In half of the studies, the female gender, depression, familial suicidal history, and drug addiction were associated with suicidal ideation. The factors of depression and drug addiction were significantly associated with suicidal attempts. Other factors found to be related to suicidal attempts among medical students were excessive academic pressure, parental divorce, blackmailing, extramarital issues, substance use, and failure in the professional examination. | Parents’ high expectations and failure to pass any subject were found to not be significantly associated with suicidal ideation. The meta-analysis of the data from two studies showed that drug addiction/substance use (OR = 0.52, I2 = 75%) is associated with suicide and that female gender (OR = 1.24, I2 = 48%) is associated with suicidal ideation. These associations are not statistically significant. | The pooled prevalence of lifetime suicidal behaviors was 25% (I2 = 91%) for suicidal ideation, 6% (I2 = 91%) for suicidal plan and 8% (I2 = 96%) for suicidal attempt. | - | Future research should focus on employing qualitative methods to better understand the underlying causes of suicidal behaviors among medical students so that strategic preventative measures to reduce the number of deaths by suicide can be developed. Universities should employ routine screening for suicidal behaviors to allow vulnerable students to receive care. |
(Rotenstein et al., 2016) | Up until 17 September 2016. | 24 of a total 195 study addressed suicidal behaviors; systematic review and meta-analysis. | North America (n = 5), South America (n = 2), Asia (n = 9), Europe (n = 4), Africa (n = 3), Not specified (n = 1). | To estimate the prevalence of depression, depressive symptoms, and suicidal ideation among medical students. | 21,002 medical students. | Minimal asymmetry of the funnel plot of studies involving suicidal ideation suggested a lack of significant publication bias. | Not a primary focus. | - | Crude summary prevalence of suicidal ideation reported as having occurred within the past 2 weeks to 12 months was 11.1% (I2 = 95.8%). Prevalence range was 4.9% to 35.6% between individual studies. Stratified meta-analyses showed that suicidal ideation prevalence estimates varied widely by screening tool and time frame, ranging from 7.4% (I2 = 0%) (PHQ-9, past 2 weeks) to 24.2% (I2 = 94.6%) (GHQ-28, past 12 months). Median prevalence over past 12 months reported by 7 studies was 10.2% (I2 = 96.6%). | - | There is a need for future research to investigate the root causes of emotional distress among medical students. Moreover, future studies should focus on identifying strategies to prevent and treat both depression and suicidal ideation with this population. |
(Seo et al., 2021) | Up until 19 March 2021. | 25; meta-analysis. | Africa (n = 4) Asia (n = 13) North America (n = 7) South America (n = 1). | To provide an overview of risk factors for both suicidal ideation and suicide attempt among medical students associated with each risk factor. | 26,111 medical students. | No evidence of significant publication bias. | The meta-analysis showed that female gender (OR = 1.47, I2 = 78%), experience of parental neglect (OR = 2.53, I2 = 71%), living alone (OR = 2.15, I2= 0%), alcohol use (OR = 1.42, I2 = 54%), personal history of physical or sexual abuse (OR = 2.57, I2 = 0%), history of physical assault (OR = 3.30, I2 = 0%), comorbid mental illness (OR = 5.08, I2 = 61%), having poor social support (OR = 3.15, I2 = 47%), experiencing academic difficulty (OR = 2.23, I2 = 30%), thinking of dropping out of school (OR = 3.01, I2 = 0%), and being from a low-income status family/being in substantial debt (OR = 1.48, I2 = 55%) were significant risk factors for suicidal ideation. Additionally, it showed that clinical students were more likely to engage in suicidal ideation than preclinical students (OR = 1.71, I2 = 50%). Depression (OR = 6.87, I2 = 69%), anxiety (OR = 3.02, I2 = 0%), burnout (OR = 6.29, I2 = 69%), sleep difficulty (OR = 3.72, I2 = 75%), and stress (OR = 3.72, I2 = 92%) were also shown to be significant risk factors. For suicidal attempts, only depression was a significant risk factor (OR = 10.34, I2 = 0%). | Smoking cigarettes, family history of mental illness, and family history of suicidal behavior were not significant risk factors for suicidal ideation. Stress, female gender, and alcohol use were not significant risk factors for suicidal attempts. | Not a primary focus. | Female gender as a risk factor for suicidal attempts only trended towards significance based on the data of 3 studies. | Future research should conduct direct statistical analysis using validated scales to discern unique risk factors related to medical students versus the general population. Future research on suicidal behavior among medical students should clearly distinguish between suicidal ideation and suicide attempts, while also exploring additional potential predictors of SA to help fill existing gaps in the literature. More research on risk factors is needed so that suicide prevention programs may be constructed for medical students. |
(Tsegay et al., 2020) | Up until 2020. | 14; Systematic Review and Meta-Analysis. | North America (n = 2), South America (n = 1), Europe (n = 5), Asia (n = 5), Africa (n = 2). | To analyze the global lifetime and one-year prevalence estimates of suicidal attempts among medical students. | 26,393 medical students. | no evidence of significant publication bias for prevalence of lifetime suicidal attempt. Not assessed for 12-month attempts. | Not a primary focus. | - | The pooled prevalence of lifetime suicidal attempts among medical students was 2.19% (I2 = 97.91%). The pooled 12-month prevalence of suicidal attempts was 1.64% (I2 = 87.31%). | The pooled prevalence for lifetime suicidal attempt was higher in low and middle-income countries (4.02% (I2 = 88.42%)) than for high-income countries (1.60% (I2 = 56.12%)). It was also higher for female students (7.32% (I2 = 96.20%)) than for male students (3.85% (I2 = 73.64%)). The 12-month prevalence of attempts was higher among male students (6.37% (I2 = 23.3%)) than female students (3.20% (I2 = 0.00%)). Lifetime prevalences of attempts are higher than the general population in China, Malaysia, and the general populations of Europe. | Early screening and interventions for suicidal attempts among medical students are likely needed to prevent adverse outcomes. |
(Wang et al., 2023) | January 2000–December 2020. | 88 of a total of 197 studies addressed suicidal behaviors; Systematic Review and Meta-Analysis | Asia (n = 88) | To estimate the prevalence of common mental disorders of depression, anxiety, and suicidal behaviors among medical students in China. | 215,880 medical students. | There was evidence of publication bias for both prevalence of suicidal ideation and attempts. | Not a primary focus. | - | Pooled prevalence was 13% (I2 = 99.19%) for suicidal ideation, 3% (I2 = 99.01%) for suicidal attempt and 4% (I2 = 97.12%) for suicide plan. | Prevalence of suicidal ideation and attempts were highest in central China. | Formulating of effective preventative efforts and increasing the accessibility of mental health services for medical students should be the focus of future efforts. Interventional studies are also needed. |
(Zeng et al., 2019) | Up until 2018. | 3 of a total of 10 studies addressed suicidal behaviors; meta-analysis. | Asia (n = 3) | To provide a comprehensive insight into the prevalent mental health experienced by Chinese medical students as well as a basis for intervening in these problems. | 3086 medical students. | The funnel plots indicated a possible publication bias. | Not a primary focus. | - | Prevalence of suicidal ideation was 11% (I2 = 97%) in Chinese medical students. | Female medical students (34%) had a relatively higher prevalence of suicidal ideation compared to male students (20%) although the difference was not statistically significant. | Longitudinal investigations with dynamic study designs are recommended for future research. Future studies are needed to investigate a wider variety of mental health problems. Timely screening and proper intervention are needed to address the prevalent mental health crisis among medical students in China. |
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Agyapong-Opoku, F.; Agyapong-Opoku, N.; Agyapong, B.; Greenshaw, A. Suicidal Behaviors Among Medical Students: A Scoping Review of Systematic Reviews and Meta-Analyses. Behav. Sci. 2025, 15, 1215. https://doi.org/10.3390/bs15091215
Agyapong-Opoku F, Agyapong-Opoku N, Agyapong B, Greenshaw A. Suicidal Behaviors Among Medical Students: A Scoping Review of Systematic Reviews and Meta-Analyses. Behavioral Sciences. 2025; 15(9):1215. https://doi.org/10.3390/bs15091215
Chicago/Turabian StyleAgyapong-Opoku, Felix, Nadine Agyapong-Opoku, Belinda Agyapong, and Andrew Greenshaw. 2025. "Suicidal Behaviors Among Medical Students: A Scoping Review of Systematic Reviews and Meta-Analyses" Behavioral Sciences 15, no. 9: 1215. https://doi.org/10.3390/bs15091215
APA StyleAgyapong-Opoku, F., Agyapong-Opoku, N., Agyapong, B., & Greenshaw, A. (2025). Suicidal Behaviors Among Medical Students: A Scoping Review of Systematic Reviews and Meta-Analyses. Behavioral Sciences, 15(9), 1215. https://doi.org/10.3390/bs15091215