The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Data Acquisition
2.3. Data Preprocessing
2.4. Data Analysis
2.4.1. Network Construction
2.4.2. Network Analysis
2.4.3. Statistical Analysis
3. Results
3.1. The Difference in the Development of Topology in the ToM Network
3.2. Associations between Topological Metrics and Severity of ASD Symptoms
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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ASD (n = 77) | TD (n = 40) | t | p | |
---|---|---|---|---|
Age (years) | 10.51 (2.86) 6~16.25 | 9.54(2.58) 6~16.58 | 1.780 | 0.078 |
VIQ | 105.79 (17.44) | 106.05 (13.72) | −0.081 | 0.936 |
PIQ | 104.68 (14.36) | 108.85 (12.66) | −1.536 | 0.127 |
FSIQ | 101.47 (14.85) | 105.10 (12.10) | −1.322 | 0.189 |
ADOS communication | 2.21 (1.50) | |||
ADOS social | 6.79 (2.15) |
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Cao, W.; Zhu, H.; Li, Y.; Wang, Y.; Bai, W.; Lao, U.; Zhang, Y.; Ji, Y.; He, S.; Zou, X. The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study. Brain Sci. 2021, 11, 120. https://doi.org/10.3390/brainsci11010120
Cao W, Zhu H, Li Y, Wang Y, Bai W, Lao U, Zhang Y, Ji Y, He S, Zou X. The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study. Brain Sciences. 2021; 11(1):120. https://doi.org/10.3390/brainsci11010120
Chicago/Turabian StyleCao, Wei, Huilin Zhu, Yan Li, Yu Wang, Wuxia Bai, Uchong Lao, Yingying Zhang, Yan Ji, Sailing He, and Xiaobing Zou. 2021. "The Development of Brain Network in Males with Autism Spectrum Disorders from Childhood to Adolescence: Evidence from fNIRS Study" Brain Sciences 11, no. 1: 120. https://doi.org/10.3390/brainsci11010120