Comprehensive Assessment of Acute Isolated or Prominent Dysarthria in the Emergency Department: A Neuro-Emergency Expert’s Experience beyond Stroke
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Patient Selection
2.2. Data Collection
2.3. Statistical Analyses
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | Isolated Dysarthria | Prominent Dysarthria | p-Value |
---|---|---|---|
(n = 28) | (n = 47) | ||
Age, years | 70.0 (58.0–79.0) | 71.0 (60.0–80.0) | 0.793 |
Age group, years * | |||
40–59 | 7 (25.0) | 12 (25.5) | 0.836 |
60–79 | 14 (50.0) | 21 (44.7) | |
≥80 | 7 (25.0) | 14 (29.8) | |
Male | 16 (57.1) | 28 (59.6) | 0.713 |
Onset-to-door time, min | 689.0 (87.0–1350.0) | 1283.0 (411.0–4020.0) | 0.042 |
Coexisting condition | |||
Hypertension | 20 (71.4) | 26 (55.3) | 0.166 |
Diabetes mellitus | 9 (32.1) | 14 (29.8) | 0.831 |
Dyslipidemia | 5 (17.9) | 9 (19.1) | 0.890 |
Current smoker | 4 (14.3) | 3 (6.4) | 0.413 |
Atrial fibrillation | 0 (0.0) | 2 (4.3) | 0.526 |
Ischemic stroke | 1 (3.6) | 1 (2.1) | 0.707 |
Coronary artery disease | 0 (0.0) | 3 (6.4) | 0.289 |
Chronic renal disease | 2 (7.1) | 3 (6.4) | 0.898 |
Antithrombotic agent | |||
Aspirin | 3 (10.7) | 10 (21.3) | 0.348 |
Clopidogrel | 3 (10.7) | 2 (4.3) | 0.356 |
Rivaroxaban | 0 (0.0) | 1 (2.1) | 0.437 |
Variables | Total | Isolated Dysarthria | Prominent Dysarthria |
---|---|---|---|
(n = 75) | (n = 28) | (n = 47) | |
Stroke | 52 (69.3) | 18 (64.3) | 34 (72.3) |
AIS | 37 (49.3) | 11 (39.3) | 26 (55.3) |
TIA | 14 (18.7) | 7 (25.0) | 7 (14.9) |
ICH | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Non-stroke | 23 (30.7) * | 10 (35.7) * | 13 (27.7) * |
Metabolic | 7 (9.3) | 3 (10.7) | 4 (8.5) |
Toxic | 6 (8.0) | 4 (14.3) | 2 (4.3) |
Brain tumor | 2 (2.7) | 1 (3.6) | 1 (2.1) |
Parkinson disease | 2 (2.7) | 1 (3.6) | 1 (2.1) |
Multiple sclerosis | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Seizure | 1 (1.3) | 1 (3.6) | 0 (0.0) |
Multiple cranial neuropathy | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Aortic dissection | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Appendicitis | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Psychiatric | 1 (1.3) | 0 (0.0) | 1 (2.1) |
Additional Neurologic Symptoms | Total * | Non-Stoke * | Stroke * |
---|---|---|---|
(n = 47) | (n = 13) | (n = 34) | |
Gait disturbance/imbalance | 9 (19.2) | 1 (7.7) | 8 (23.5) |
Facial palsy | 8 (17.0) | 1 (7.7) | 7 (20.6) |
Mild hemiparesis | 5 (10.6) | 2 (15.4) | 3 (8.8) |
Dizziness | 4 (8.5) | 3 (23.1) | 1 (2.9) |
Limb ataxia | 3 (6.4) | 0 (0.0) | 3 (8.8) |
Sensory change | 3 (6.4) | 0 (0.0) | 3 (8.8) |
Transient motor weakness | 3 (6.4) | 0 (0.0) | 3 (8.8) |
Swallowing difficulty | 2 (4.3) | 1 (7.7) | 1 (2.9) |
Acute memory loss | 1 (2.1) | 1 (7.7) | 0 (0.0) |
Chest pain | 1 (2.1) | 1 (7.7) | 0 (0.0) |
Diplopia | 1 (2.1) | 0 (0.0) | 1 (2.9) |
Fever | 1 (2.1) | 1 (7.7) | 0 (0.0) |
Headache | 1 (2.1) | 0 (0.0) | 1 (2.9) |
Hip pain | 1 (2.1) | 0 (0.0) | 1 (2.9) |
Leg weakness | 1 (2.1) | 0 (0.0) | 1 (2.9) |
Drowsy mentality | 1 (2.1) | 1 (7.7) | 0 (0.0) |
Tongue palsy | 1 (2.1) | 1 (7.7) | 0 (0.0) |
Blurred vision | 1 (2.1) | 0 (0.0) | 1 (2.9) |
Variables | Isolated Dysarthria | Prominent Dysarthria | p-Value |
---|---|---|---|
(n = 18) | (n = 33) | ||
Clinical diagnosis | 0.204 | ||
Ischemic stroke | 11 (61.1) | 26 (78.8) | |
TIA | 7 (38.9) | 7 (21.2) | |
DWI positivity | 12 (66.7) | 29 (87.9) | 0.154 |
Single and small lesion | 10 (83.3) | 16 (55.2) | |
Multiple or territorial lesions | 2 (16.7) | 13 (44.8) | |
NIHSS at admission to ED in DWI positivity | <0.001 | ||
0 | 2 (16.7) | 3 (10.3) | |
1 | 11 (83.3) | 4 (13.8) | |
2 | 0 (0.0) | 14 (48.3) | |
3 | 0 (0.0) | 5 (17.2) | |
4 | 0 (0.0) | 3 (10.3) | |
TOAST in DWI positivity | 0.566 | ||
1 | 3 (25.0) | 7 (24.1) | |
2 | 8 (66.7) | 15 (51.7) | |
3 | 0 (0.0) | 4 (13.8) | |
4 | 0 (0.0) | 0 (0.0) | |
5 | 1 (8.3) | 3 (10.3) |
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Lee, S.-H.; Ha, S.-O.; Kim, J.-H.; Yang, W.-S.; Park, Y.-S.; Park, T.-J. Comprehensive Assessment of Acute Isolated or Prominent Dysarthria in the Emergency Department: A Neuro-Emergency Expert’s Experience beyond Stroke. Brain Sci. 2022, 12, 1047. https://doi.org/10.3390/brainsci12081047
Lee S-H, Ha S-O, Kim J-H, Yang W-S, Park Y-S, Park T-J. Comprehensive Assessment of Acute Isolated or Prominent Dysarthria in the Emergency Department: A Neuro-Emergency Expert’s Experience beyond Stroke. Brain Sciences. 2022; 12(8):1047. https://doi.org/10.3390/brainsci12081047
Chicago/Turabian StyleLee, Soon-Ho, Sang-Ook Ha, Jin-Hyouk Kim, Won-Seok Yang, Young-Sun Park, and Tae-Jin Park. 2022. "Comprehensive Assessment of Acute Isolated or Prominent Dysarthria in the Emergency Department: A Neuro-Emergency Expert’s Experience beyond Stroke" Brain Sciences 12, no. 8: 1047. https://doi.org/10.3390/brainsci12081047