Vaccination against Paediatric Respiratory Pathogens
Abstract
:1. Introduction
2. Respiratory Pathogens and Available Vaccines
2.1. Influenza Vaccination
2.2. Pneumococcal Vaccination
2.3. Pertussis Vaccination
2.4. Measles Vaccination
2.5. Respiratory Syncytial Virus (RSV)
3. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Naz, R.; Gul, A.; Javed, U.; Urooj, A.; Amin, S.; Fatima, Z. Etiology of acute viral respiratory infections common in Pakistan: A review. Rev. Med. Virol. 2019, 29, e2024. [Google Scholar] [CrossRef] [PubMed]
- Chen, J.; Hu, P.; Zhou, T.; Zheng, T.; Zhou, L.; Jiang, C.; Pei, X. Epidemiology and clinical characteristics of acute respiratory tract infections among hospitalizedinfants and young children in Chengdu, West China, 2009–2014. BMC Pediatr. 2018, 18, 216. [Google Scholar] [CrossRef] [PubMed]
- Shi, T.; McLean, K.; Campbell, H.; Nair, H. Aetiological role of common respiratory viruses in acute lower respiratory infections in children under five years: A systematic review and meta-analysis. J. Glob. Health 2015, 5, 010408. [Google Scholar] [CrossRef]
- Nair, H.; Simões, E.A.F.; Rudan, I.; Gessner, B.D.; Azziz-Baumgartner, E.; Zhang, J.S.F.; Daniel, R.M.D.; Mackenzie, G.A.; Moiïsi, G.C.; Roca, A.; et al. Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: A systematic analysis. Lancet 2013, 381, 1380–1390. [Google Scholar] [CrossRef]
- Nohynek, H.; Madhi, S.; Grijalva, C.G. Childhood bacterial respiratory diseases: Past, present, and future. Pediatr. Infect. Dis. J. 2009, 28, 127–132. [Google Scholar] [CrossRef]
- Esposito, S.; Bianchini, S.; Polinori, I.; Principi, N. Impact of OM-85 Given during Two Consecutive Years to Children with a History of Recurrent Respiratory Tract Infections: A Retrospective Study. Int. J. Environ. Res. Public Health 2019, 16, E1065. [Google Scholar] [CrossRef]
- Chakhunashvili, G.; Wagner, A.L.; Power, L.E.; Janusz, C.B.; Machablishvili, A.; Karseladze, I.; Olgha, T.M.; Khatuna, Z.; Paata, I.; Gregory, C.G.; et al. Severe Acute Respiratory Infection (SARI) sentinel surveillance in the country of Georgia, 2015–2017. PLoS ONE 2018, 13, e0201497. [Google Scholar] [CrossRef]
- Schluger, N.W.; Koppaka, R. Lung disease in a global context. A call for public health action. Ann. Am. Thorac. Soc. 2014, 11, 407–416. [Google Scholar] [CrossRef]
- Wardlaw, T.; Salama, P.; Johansson, E.W.; Mason, E. Pneumonia: The leading killer of children. Lancet 2006, 368, 1048–1050. [Google Scholar] [CrossRef]
- O’Brien, K.L.; Wolfson, L.J.; Watt, J.P.; Henkle, E.; Deloria-Knoll, M.; McCall, N.; Lee, E.; Mulholland, P.K.; Levine, O.S.; Cherian, T.; et al. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: Global estimates. Lancet 2009, 374, 893–902. [Google Scholar] [CrossRef]
- Liu, L.; Oza, S.; Hogan, D.; Chu, Y.; Perin, J.; Zhu, J.; Lawn, J.E.; Cousens, S.; Mathers, C.; Black, R.E. Global, regional, and national causes of under-5 mortality in 2000-15: An updated systematic analysis with implications for the sustainable development goals. Lancet 2016, 388, 3027–3035. [Google Scholar] [CrossRef]
- Bogaert, D.; De Groot, R.; Hermans, P.W. Streptococcus pneumoniae colonisation: The key to pneumococcal disease. Lancet Infect. Dis. 2004, 4, 144–154. [Google Scholar] [CrossRef]
- Nair, H.; Brooks, W.A.; Katz, M.; Roca, A.; Berkley, J.A.; Madhi, S.A.; Simmerman, J.M.; Gordon, A.; Sato, M.; Howie, S.; et al. Global burden of respiratory infections due to seasonal influenza in young children: A systematic review and meta-analysis. Lancet 2011, 378, 1917–1930. [Google Scholar] [CrossRef]
- Verhagen, L.M.; Luesink, M.; Warris, A.; de Groot, R.; Hermans, P.W. Bacterial respiratory pathogens in children with inherited immune and airway disorders: Nasopharyngeal carriage and disease risk. Pediatr. Infect. Dis. J. 2013, 32, 399–404. [Google Scholar] [CrossRef] [PubMed]
- Doan, Q.; Enarson, P.; Kissoon, N.; Klassen, T.P.; Johnson, D.W. Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst. Rev. 2014, 15, 006452. [Google Scholar] [CrossRef]
- Bashir, U.; Nisar, N.; Arshad, Y.; Alam, M.M.; Ashraf, A.; Sadia, H.; Kazi, B.M.; Zaidi, S.S. Respiratory syncytial virus and influenza are the key viral pathogens in children <2 years hospitalized with bronchiolitis and pneumonia in Islamabad Pakistan. Arch Virol. 2017, 162, 763–773. [Google Scholar]
- García-García, M.L.; Calvo, C.; Rey, C.; Díaz, B.; Molinero, M.D.; Pozo, F.; Casas, I. Human metapnuemovirus infections in hospitalized children and comparison with other respiratory viruses. 2005–2014 prospective study. PLoS ONE 2017, 12, e0173504. [Google Scholar] [CrossRef]
- Sung, R.Y.; Chan, P.K.; Tsen, T.; Li, A.M.; Lam, W.Y.; Yeung, A.C.; Nelson, E.A. Identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in Hong Kong by multiplex PCR assays. J. Med. Virol. 2009, 81, 153–159. [Google Scholar] [CrossRef]
- Ruuskanen, O.; Lahti, E.; Jennings, L.C.; Murdoch, D.R. Viral pneumonia. Lancet 2011, 377, 1264–1275. [Google Scholar] [CrossRef]
- Tregoning, J.S.; Schwarze, J. Respiratory viral infections in infants: Causes, clinical symptoms, virology, and immunology. Clin. Microbiol. Rev. 2010, 23, 74–98. [Google Scholar] [CrossRef]
- Thorburn, K.; Riordan, A. Pulmonary bacterial coinfection in infants and children with viral respiratory infection. Expert Rev. Anti Infect. Ther. 2012, 10, 909–916. [Google Scholar] [CrossRef] [PubMed]
- McCullers, J.A. The co-pathogenesis of influenza viruses with bacteria in the lung. Nat. Rev. Microbiol. 2014, 12, 252–262. [Google Scholar] [CrossRef] [PubMed]
- McCarthy, N.L.; Gee, J.; Sukumaran, L.; Weintraub, E.; Duffy, J.; Kharbanda, E.O.; Baxter, R.; Irving, S.; King, J.; Daley, M.F.; et al. Vaccination and 30-Day Mortality Risk in Children, Adolescents, and Young Adults. Pediatrics 2016, 137, e20152970. [Google Scholar] [CrossRef] [PubMed]
- Marchisio, P.; Baggi, E.; Bianchini, S.; Principi, N.; Esposito, S. Clinical and socioeconomic impact of pediatric seasonal and pandemic influenza. Hum. Vaccin. Immunother. 2012, 8, 17–20. [Google Scholar] [CrossRef]
- Principi, N.; Esposito, S. Influenza vaccine use to protect healthy children: A debated topic. Vaccine 2018, 28, 5391–5396. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. Influenza vaccination in pediatric age. Expert. Rev. Vaccines 2015, 14, 785–787. [Google Scholar] [CrossRef] [Green Version]
- Antonova, E.N.; Rycroft, C.E.; Ambrose, C.S.; Heikkinen, T.; Principi, N. Burden of paediatric influenza in Western Europe: A systematic review. BMC Public Health 2012, 12, 968. [Google Scholar] [CrossRef]
- Esposito, S.; Mencacci, A.; Cenci, E.; Camilloni, B.; Silvestri, E.; Principi, N. Multiplex Platforms for the Identification of Respiratory Pathogens: Are They Useful in Pediatric Clinical Practice? Front. Cell. Infect. Microbiol. 2019, 9, 196. [Google Scholar] [CrossRef]
- Lafond, K.E.; Nair, H.; Rasooly, M.H.; Valente, F.; Booy, R.; Rahman, M.; Kitsutani, P.; Yu, H.; Guzman, G.; Coulibaly, D.; et al. Global role and burden of influenza in pediatric respiratory hospitalizations, 1982–2012: A systematic analysis. PLoS Med. 2016, 13, e1001977. [Google Scholar] [CrossRef]
- Heikkinen, T.; Silvennoinen, H.; Heinonen, S.; Vuorinen, T. Clinical and socioeconomic impact of moderate-to-severe versus mild influenza in children. Eur. J. Clin. Microbiol. Infect. Dis. 2016, 35, 1107–1113. [Google Scholar] [CrossRef] [Green Version]
- Principi, N.; Esposito, S. Protection of children against influenza: Emerging problems. Protection of children against influenza: Emerging problems. Hum. Vaccin. Immunother. 2018, 14, 750–757. [Google Scholar] [CrossRef] [PubMed]
- Principi, N.; Camilloni, B.; Esposito, S. ESCMID Vaccine Study Group (EVASG). Influenza immunization policies: Which could be the main reasons for differences among countries? Hum. Vaccin. Immunother. 2018, 14, 684–692. [Google Scholar] [CrossRef] [PubMed]
- Paules, C.; Subbarao, K. Influenza. Influenza. Lancet 2017, 390, 697–708. [Google Scholar] [CrossRef]
- Mistry, R.D.; Fischer, J.B.; Prasad, P.A.; Coffin, S.E.; Alpern, E.R. Severe complications in influenza-like illnesses. Pediatrics 2014, 134, 684–690. [Google Scholar] [CrossRef]
- Nakamura, S.; Davis, K.M.; Weiser, J.N. Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. J. Clin. Investig. 2011, 121, 3657–3665. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Opatowski, L.; Baguelin, M.; Eggo, R.M. Influenza interaction with cocirculating pathogens and its impact on surveillance, pathogenesis, and epidemic profile: A key role for mathematical modelling. PLoS Pathog. 2018, 14, e1006770. [Google Scholar] [CrossRef]
- Principi, N.; Esposito, S. Severe influenza in children: Incidence and risk factors. Expert Rev. Anti Infect. Ther. 2016, 14, 961–968. [Google Scholar] [CrossRef]
- Esposito, S.; Molteni, C.G.; Daleno, C.; Valzano, A.; Fossali, E.; Da Dalt, L.; Cecinati, V.; Bruzzese, E.; Giacchino, R.; Giaquinto, C.; et al. Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009. BMC Infect. Dis. 2011, 11, 271. [Google Scholar] [CrossRef]
- Esposito, S.; Cantarutti, L.; Molteni, C.G.; Daleno, C.; Scala, A.; Tagliabue, C.; Pelucchi, C.; Giaquinto, C.; Principi, N. Clinical manifestations and socio-economic impact of influenza among healthy children in the community. J. Infect. 2011, 62, 379–387. [Google Scholar] [CrossRef]
- Piralla, A.; Lunghi, G.; Ruggiero, L.; Girello, A.; Bianchini, S.; Rovida, F.; Caimmi, S.; Marseglia, G.L.; Principi, N.; Baldanti, F.; et al. Molecular epidemiology of influenza B virus among hospitalized pediatric patients in Northern Italy during the 2015-16 season. PLoS ONE 2017, 12, e0185893. [Google Scholar] [CrossRef]
- Esposito, S. 100 years since the 1918 influenza pandemic. Hum. Vaccin. Immunother. 2018, 14, 504–507. [Google Scholar] [CrossRef] [PubMed]
- Chong, Y.; Ikematsu, H. Is seasonal vaccination a contributing factor to the selection of influenza epidemic variants? Hum. Vaccin. Immunother. 2018, 14, 518–522. [Google Scholar] [CrossRef] [PubMed]
- Treanor, J.J.; Talbot, H.K.; Ohmit, S.E.; Coleman, L.A.; Thompson, M.G.; Cheng, P.Y.; Petrie, J.G.; Lofthus, G.; Meece, J.K.; Williams, J.V.; et al. US Flu-VE Network. Effectiveness of seasonal influenza vaccines in the United States during a season with circulation of all three vaccine strains. Clin. Infect. Dis. 2012, 55, 951–959. [Google Scholar] [CrossRef] [PubMed]
- Ferdinands, J.M.; Olsho, L.E.; Agan, A.A.; Bhat, N.; Sullivan, R.M.; Hall, M.; Mourani, P.M.; Thompson, M.; Randolph, A.G. Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010–2012. J. Infect. Dis. 2014, 210, 674–683. [Google Scholar] [CrossRef] [PubMed]
- Principi, N.; Senatore, L.; Esposito, S. Protection of young children from influenza through universal vaccination. Hum. Vaccin. Immunother. 2015, 11, 2350–2358. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Centers for Disease Control and Prevention (CDC), Advisory Committee for Immunization Practices (ACIP). Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger, United States. 2019. Available online: https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html#note-flu (accessed on 22 May 2019).
- Grohskopf, L.A.; Sokolow, L.Z.; Broder, K.R.; Olsen, S.J.; Karron, R.A.; Jernigan, D.B.; Bresee, J.S. Prevention and Control of Seasonal Influenza with Vaccines; Recommendations and reports: Morbidity and Mortality Weekly Report; Centers for Disease Control and Prevention: Atlanta, GA, USA, 2016; Volume 65, p. 54. [Google Scholar]
- Esposito, S.; Principi, N. European Society of Clinical Microbiology Infectious Diseases (ESCMID) Vaccine Study Group (EVASG). Influenza vaccination and prevention of antimicrobial resistance. Expert Rev. Vaccines 2018, 17, 881–888. [Google Scholar] [CrossRef] [PubMed]
- Poehling, K.A.; Szilagyi, P.G.; Staat, M.A.; Snively, B.M.; Payne, D.C.; Bridges, C.B.; Chu, S.Y.; Light, L.S.; Prill, M.M.; Finelli, L.; et al. New Vaccine Surveillance Network. Impact of maternal immunization on influenza hospitalizations in infants. Am. J. Obstet. Gynecol. 2011, 204, 141–148. [Google Scholar] [CrossRef]
- Eick, A.A.; Uyeki, T.M.; Klimov, A.; Hall, H.; Reid, R.; Santosham, M.; O’Brien, K.L. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch. Pediatr. Adolesc. Med. 2011, 165, 104–111. [Google Scholar] [CrossRef]
- Nunes, M.C.; Cutland, C.L.; Jones, S.; Downs, S.; Weinberg, A.; Ortiz, J.R.; Neuzil, K.M.; Simões, E.A.F.; Klugman, K.P.; Madhi, S.A. Efficacy of Maternal Influenza Vaccination Against All-Cause Lower Respiratory Tract Infection Hospitalizations in Young Infants: Results from a Randomized Controlled Trial. Clin. Infect. Dis. 2017, 65, 1066–1071. [Google Scholar] [CrossRef]
- Zaman, K.; Roy, E.; Arifeen, S.E.; Rahman, M.; Raqib, R.; Wilson, E.; Omer, S.B.; Shahid, N.S.; Breiman, R.F.; Steinhoff, M.C. Effectiveness of maternal influenza immunization in mothers and infants. N. Engl. J. Med. 2008, 359, 1555–1564. [Google Scholar] [CrossRef]
- Esposito, S.; Bosis, S.; Morlacchi, L.; Baggi, E.; Sabatini, C.; Principi, N. Can infants be protected by means of maternal vaccination? Clin. Microbiol. Infect. 2012, 18, 85–92. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Domenech, M.; Sempere, J.; de Miguel, S.; Yuste, J. Combination of Antibodies and Antibiotics as a Promising Strategy Against Multidrug-Resistant Pathogens of the Respiratory Tract. Front. Immunol. 2018, 9, 2700. [Google Scholar] [CrossRef] [PubMed]
- Knight, G.M.; Clarkson, M.; de Silva, T.I. Potential impact of influenza vaccine roll-out on antibiotic use in Africa. J. Antimicrob. Chemother. 2018, 73, 2197–2200. [Google Scholar] [CrossRef] [PubMed]
- Meek, R.W.; Vyas, H.; Piddock, L.J. Nonmedical Uses of Antibiotics: Time to Restrict Their Use? PLoS Biol. 2015, 13, e1002266. [Google Scholar] [CrossRef]
- Ruf, B.R.; Knuf, M. The burden of seasonal and pandemic influenza in infants and children. Eur. J. Pediatr. 2014, 173, 265–276. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. Different influenza vaccine formulations and adjuvants for childhood influenza vaccination. Vaccine 2011, 29, 7535–7541. [Google Scholar] [CrossRef]
- Principi, N.; Di Cara, G.; Bizzarri, I.; Isidori, C.; Borgia, P.; Mignini, C.; Saponara, M.; Argentiero, A.; Esposito, S. Prevention of Invasive Pneumococcal Disease: Problems Emerged after Some Years of the 13-Valent Pneumococcal Conjugate Vaccine Use. Curr. Infect. Dis. Rep. 2018, 20, 1. [Google Scholar] [CrossRef]
- Azzari, C.; Serranti, D.; Nieddu, F.; Moriondo, M.; Casini, A.; Lodi, L.; de Benedictis, F.M.; De Vitis, E.; Cavone, F.; Cortimiglia, M.; et al. Significant impact of pneumococcal conjugate vaccination on pediatric parapneumonic effusion: Italy 2006–2018. Vaccine 2019, 37, 2704–2711. [Google Scholar] [CrossRef]
- Shigayeva, A.; Rudnick, W.; Green, K.; Chen, D.K.; Demczuk, W.; Gold, W.L.; Johnstone, J.; Kitai, I.; Krajden, S.; Lovinsky, R.; et al. Toronto Invasive Bacterial Diseases Network. Invasive Pneumococcal Disease Among Immunocompromised Persons: Implications for Vaccination Programs. Clin. Infect. Dis. 2016, 62, 139–147. [Google Scholar] [CrossRef]
- Esposito, S.; Colombo, C.; Tosco, A.; Montemitro, E.; Volpi, S.; Ruggiero, L.; Lelii, M.; Bisogno, A.; Pelucchi, C.; Principi, N.; et al. Italian Pneumococcal Study Group on Cystic Fibrosis. Streptococcus pneumoniae oropharyngeal colonization in children and adolescents with cysticfibrosis. J. Cyst. Fibros. 2016, 15, 366–371. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. European Society of Clinical Microbiology and Infectious Diseases Escmid Vaccine Study Group Evasg1. Strategies to develop vaccines of pediatric interest. Expert Rev. Vaccines 2017, 16, 175–186. [Google Scholar] [CrossRef] [PubMed]
- Black, S.; Shinefield, H.; Baxter, R.; Austrian, R.; Bracken, L.; Hansen, J.; Lewis, E.; Fireman, B. Postlicensure surveillance for pneumococcal invasive disease after use of heptavalent pneumococcal conjugate vaccine in Northern California Kaiser Permanente. Pediatr. Infect. Dis. J. 2004, 23, 485–489. [Google Scholar] [CrossRef] [PubMed]
- Van Werkhoven, C.H.; Huijts, S.M. Vaccines to Prevent Pneumococcal Community—Acquired Pneumonia. Clin. Chest Med. 2018, 39, 733–752. [Google Scholar] [CrossRef] [PubMed]
- Principi, N.; Esposito, S. Prevention of Community-Acquired Pneumonia with Available Pneumococcal Vaccines. Int. J. Mol. Sci. 2016, 18, E30. [Google Scholar] [CrossRef] [PubMed]
- Mrkvan, T.; Pelton, S.I.; Ruiz-Guiñazú, J.; Palmu, A.A.; Borys, D. Effectiveness and impact of the 10-valent pneumococcal conjugate vaccine, PHiD-CV: Review of clinical trials and post-marketing experience. Expert Rev. Vaccines 2018, 17, 797–818. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. ESCMID Vaccine Study Group. Direct and indirect effects of the 13-valent pneumococcal conjugate vaccine administered to infants and young children. Future Microbiol. 2015, 10, 1599–1607. [Google Scholar] [CrossRef]
- Principi, N.; Esposito, S. The impact of 10-valent and 13-valent pneumococcal conjugate vaccines on serotype 19A invasive pneumococcal disease. Expert Rev. Vaccines 2015, 14, 1359–1366. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. Pneumococcal immunization with conjugate vaccines: Are 10-Valent and 13-Valent vaccines similar? Future Microbiol. 2019, 921–923. [Google Scholar] [CrossRef]
- Argondizo-Correia, C.; Rodrigues, A.K.S.; de Brito, C.A. Neonatal Immunity to Bordetella pertussis Infection and Current Prevention Strategies. J. Immunol. Res. 2019, 2019, 7134168. [Google Scholar] [CrossRef]
- Principi, N.; Litt, D.; Terranova, L.; Picca, M.; Malvaso, C.; Vitale, C.; Fry, N.K.; Esposito, S. The Italian Pertussis Group for Persistent Cough in Children. Pertussis-associated persistent cough in previously vaccinated children. J. Med. Microbiol. 2017, 66, 1699–1702. [Google Scholar] [CrossRef]
- Melvin, J.A.; Scheller, E.V.; Miller, J.F.; Cotter, P.A. Bordetella pertussis pathogenesis: Current and future challenges. Nat. Rev. Microbiol. 2014, 12, 274–288. [Google Scholar] [CrossRef] [PubMed]
- Polinori, I.; Esposito, S. Clinical Findings and Management of Pertussis. Adv. Exp. Med. Biol. 2019. [Google Scholar] [CrossRef]
- Esposito, S.; Principi, N. Prevention of pertussis: An unresolved problem. Hum. Vaccin. Immunother. 2018, 14, 2452–2459. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Marcellini, V.; Piano, M.E.; Fedele, G.; Gesualdo, F.; Pandolfi, E.; Midulla, F.; Leone, P.; Stefanelli, P.; Tozzi, A.E.; Carsetti, R. Pertussis Study Group. Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells. Front. Immunol. 2017, 8, 1158. [Google Scholar] [CrossRef] [PubMed]
- Kauhl, B.; Heil, J.; Hoebe, C.J.; Schweikart, J.; Krafft, T.; Dukers-Muijrers, N.H. Is the current pertussis incidence only the results of testing? A spatial and space-time analysis of pertussis surveillance data using cluster detection methods and geographically weightedregression modelling. PLoS ONE 2017, 12, e0172383. [Google Scholar] [CrossRef] [PubMed]
- Wilk, M.M.; Borkner, L.; Misiak, A.; Curham, L.; Allen, A.C.; Mills, K.H.G. Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis. Emerg. Microbes. Infect. 2019, 8, 169–185. [Google Scholar] [CrossRef]
- World Health Organization. Pertussis vaccines: WHO position paper—August 2015. Wkly. Epidemiol. Record 2015, 90, 433–460. [Google Scholar]
- European Centre for Disease Prevention and Control. Vaccine Schedule. Pertussis. Available online: http://vaccine-schedule.ecdc.europa.eu/pages/scheduler.aspx (accessed on 22 May 2019).
- Amirthalingam, G.; Andrews, N.; Campbell, H.; Ribeiro, S.; Kara, E.; Donegan, K.; Fry, N.K.; Miller, E.; Ramsay, M. Effectiveness of maternal pertussis vaccination in England: An observational study. Lancet 2014, 384, 1521–1528. [Google Scholar] [CrossRef]
- Romanin, V.; Acosta, A.M.; Juarez, M.D.V.; Briere, E.; Sanchez, S.M.; Cordoba, B.L.; Sevilla, M.E.; Lucion, M.F.; Urrutia, A.; Sagradini, S.; et al. Maternal Vaccination in Argentina: Tdap Vaccine Effectiveness During Pregnancy in Preventing Pertussis in Infants Less Than 2 Months of Age. Clin. Infect. Dis. 2019, 16, 217. [Google Scholar]
- Esposito, S.; Stefanelli, P.; Fry, N.K.; Fedele, G.; He, Q.; Paterson, P.; Tan, T.; Knuf, M.; Rodrigo, C.; Weil, O.C.; et al. World Association of Infectious Diseases and Immunological Disorders (WAidid) and the Vaccine Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EVASG). Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines. Front. Immunol. 2019, 10, 1344. [Google Scholar]
- Lancella, L.; Di Camillo, C.; Vittucci, A.C.; Boccuzzi, E.; Bozzola, E.; Villani, A. Measles lessons in an anti-vaccination era: Public health is a social duty, not a political option. Ital. J. Pediatr. 2017, 43, 102. [Google Scholar] [CrossRef] [PubMed]
- Moss, W.J. Measles. Lancet 2017, 390, 2490–2502. [Google Scholar] [CrossRef]
- CDC. Measles Cases and Outbreaks. Available online: https://www.cdc.gov/measles/cases-outbreaks.html (accessed on 22 May 2019).
- ECDC. Monthly Measles and Rubella Monitoring Report, May 2019. Available online: https://ecdc.europa.eu/en/publications-data/monthly-measles-and-rubella-monitoring-report-may-2019 (accessed on 22 May 2019).
- Green, C.A.; Sande, C.J.; de Lara, C.; Thompson, A.J.; Silva-Reyes, L.; Napolitano, F.; Pierantoni, A.; Capone, S.; Vitelli, A.; Klenerman, P.; et al. Humoral and cellular immunity to RSV in infants, children and adults. Vaccine 2018, 36, 6183–6190. [Google Scholar] [CrossRef] [PubMed]
- Esposito, S.; Piralla, A.; Zampiero, A.; Bianchini, S.; Di Pietro, G.; Scala, A.; Pinzani, R.; Fossali, E.; Baldanti, F.; Principi, N. Characteristics and Their Clinical Relevance of Respiratory Syncytial Virus Types and Genotypes Circulating in Northern Italy in Five Consecutive Winter Seasons. PLoS ONE 2015, 10, e0129369. [Google Scholar] [CrossRef] [PubMed]
- Bosis, S.; Esposito, S.; Niesters, H.G.; Zuccotti, G.V.; Marseglia, G.; Lanari, M.; Zuin, G.; Pelucchi, C.; Osterhaus, A.D.; Principi, N. Role of respiratory pathogens in infants hospitalized for a first episode of wheezing and their impact on recurrences. Clin. Microbiol. Infect. 2008, 14, 677–684. [Google Scholar] [CrossRef] [Green Version]
- Esposito, S.; Scarselli, E.; Lelii, M.; Scala, A.; Vitelli, A.; Capone, S.; Fornili, M.; Biganzoli, E.; Orenti, A.; Nicosia, A.; et al. Antibody response to respiratory syncytial virus infection in children <18 months old. Hum. Vaccin. Immunother. 2016, 12, 1700–1706. [Google Scholar]
- Esposito, S.; Pietro, G.D. Respiratory syncytial virus vaccines: An update on those in the immediate pipeline. Future Microbiol. 2016, 11, 1479–1490. [Google Scholar] [CrossRef]
- Behzadi, M.A.; Leyva-Grado, V.H. Overview of Current Therapeutics and Novel Candidates Against Influenza, Respiratory Syncytial Virus, and Middle East Respiratory Syndrome Coronavirus Infections. Front. Microbiol. 2019, 10, 1327. [Google Scholar] [CrossRef] [Green Version]
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Bianchini, S.; Argentiero, A.; Camilloni, B.; Silvestri, E.; Alunno, A.; Esposito, S. Vaccination against Paediatric Respiratory Pathogens. Vaccines 2019, 7, 168. https://doi.org/10.3390/vaccines7040168
Bianchini S, Argentiero A, Camilloni B, Silvestri E, Alunno A, Esposito S. Vaccination against Paediatric Respiratory Pathogens. Vaccines. 2019; 7(4):168. https://doi.org/10.3390/vaccines7040168
Chicago/Turabian StyleBianchini, Sonia, Alberto Argentiero, Barbara Camilloni, Ettore Silvestri, Anna Alunno, and Susanna Esposito. 2019. "Vaccination against Paediatric Respiratory Pathogens" Vaccines 7, no. 4: 168. https://doi.org/10.3390/vaccines7040168
APA StyleBianchini, S., Argentiero, A., Camilloni, B., Silvestri, E., Alunno, A., & Esposito, S. (2019). Vaccination against Paediatric Respiratory Pathogens. Vaccines, 7(4), 168. https://doi.org/10.3390/vaccines7040168