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Volume 10
Issue 17
10.3390/jcm10173926
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Article
Peer-Review Record

Twenty Years of Experience in Juvenile Nasopharyngeal Angiofibroma (JNA) Preoperative Endovascular Embolization: An Effective Procedure with a Low Complications Rate

J. Clin. Med. 2021, 10(17), 3926; https://doi.org/10.3390/jcm10173926
by Andrea Giorgianni 1, Stefano Molinaro 1,*, Edoardo Agosti 2, Alberto Vito Terrana 1, Francesco Alberto Vizzari 1, Alberto Daniele Arosio 3,4, Giacomo Pietrobon 5, Luca Volpi 6,7, Mario Turri-Zanoni 3,8, Giuseppe Craparo 9, Filippo Piacentino 10, Paolo Castelnuovo 3,4,8, Fabio Massimo Baruzzi 1 and Maurizio Bignami 6,7
Reviewer 1: Anonymous
Reviewer 2: Anonymous
J. Clin. Med. 2021, 10(17), 3926; https://doi.org/10.3390/jcm10173926
Submission received: 23 July 2021 / Revised: 20 August 2021 / Accepted: 23 August 2021 / Published: 31 August 2021
(This article belongs to the Special Issue Embolization Techniques: State of the Art and Future Perspectives)

Round 1

Reviewer 1 Report

The  is really interesting and well written. They report the 20-years experience in the preoperative endovascular embolization treatment of the juvenile nasopharyngeal angiofibroma (JNA). The authors performed a superselective microcatheterization of external carotid artery (ECA) feeders through injection of polyvinyl alcohol (PVA) particles. The structure is correct; however, some minor corrections are required to improve the overall quality: 

Abstract

  • please remove the text highilighted ''morbidity, and reducing postoperative residual rate. and Keywords: JNA; embolization

Methods correct and clear description

Results

  • please specify the number of each features described. Only percentage is present sometimes while conversely only numbers sometimes. Report always number (percentage)

Discussion

  • Several preoperative treatment have been described to minimize the bleeding intraoperative. Thakar et al. described significant difference between Prepubertal and postpubertal patients in their response to flutamide. Indeed, in postpubertal patients, 6 weeks preoperative may lead to partial tumor regression, facilitating surgical excision and limit morbidity. please cite the manuscript doi:10.1002/hed.21667

Author Response

Thanks. Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Many thanks for the opportunity to review this paper. I found this work very interesting, well structured, and comprehensive. I only suggest specifying the abbreviations throughout the text, and also in the chronological order of appearance (e.g., ECA-ICA at the end of the Introduction section and at the beginning of the “Endovascular embolization” paragraph should be reversed). Furthermore, in the Table 1 “Surgical time” should probably be reported in “min” and not “ml”.

Author Response

Many thanks. Please see the attachment below

Author Response File: Author Response.docx

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