Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study)
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Distribution of OP-Index Values in Patients with OPLL
3.2. Demographic Characteristics in the High and Moderate/Low OP Index Groups
3.3. Deterioration of Lumbar Spine and Lower Extremity Function in the High OP-Index Group
3.4. Higher Prevalence of Ossified Thoracic Lesions in Patients with a High OP Index
3.5. Distribution of OPLL and DISH in the High OP Index Group
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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High OP Index (n = 25) | Moderate/Low OP Index (n = 211) | p-Value | |
---|---|---|---|
Age (years) | 59.0 ± 14.0 | 64.5 ± 12.0 | 0.07 |
Male sex (%) | 32.0 | 73.5 | <0.001 *** |
Body mass index | 27.4 ± 5.8 | 25.7 ± 4.3 | 0.17 |
Diabetes mellitus (%) | 28.0 | 24.6 | 0.82 |
Cervical JOA score | 11.5 (6–17) | 12.4 (−2, 17) | 0.12 |
High OP Index (n = 25) | Moderate/Low OP Index (n = 211) | p-Value | |
---|---|---|---|
Prevalence of symptoms (%) | |||
Neck pain | 60.0 | 60.2 | 0.98 |
Back pain | 32.0 | 28.0 | 0.67 |
Low back pain | 68.0 | 52.6 | 0.14 |
JOA-CMEQ score | |||
Cervical spine function | 59.8 ± 33.8 | 66.6 ± 27.9 | 0.34 |
Upper extremity function | 74.5 ± 21.6 | 80.8 ± 21.5 | 0.18 |
Lower extremity function | 46.1 ± 35.7 | 68.3 ± 29.3 | 0.006 ** |
Bladder function | 73.0 ± 20.2 | 74.7 ± 22.3 | 0.69 |
Quality of life | 40.4 ± 20.2 | 51.0 ± 19.6 | 0.02 * |
JOA-BPEQ score | |||
Lumbar spine function | 54.0 ± 29.3 | 69.7 ± 31.6 | 0.02 * |
Social dysfunction | 43.4 ± 32.8 | 57.9 ± 28.7 | 0.04 * |
Mentality | 40.8 ± 18.6 | 50.1 ± 19.9 | 0.03 * |
Locomotive function | 45.6 ± 37.1 | 66.4 ± 34.5 | 0.01 * |
Body pain | 58.2 ± 39.1 | 72.3 ± 32.7 | 0.09 |
VAS score | |||
Neck pain | 40.2 ± 31.3 | 38.6 ± 31.2 | 0.81 |
Upper extremity numbness | 47.5 ± 34.5 | 44.8 ± 33.2 | 0.71 |
Chest constriction | 13.0 ± 27.9 | 9.9 ± 21.0 | 0.60 |
Numbness below the chest | 60.1 ± 28.9 | 34.2 ± 33.6 | <0.001 *** |
Low back pain | 44.1 ± 32.9 | 25.7 ± 27.9 | 0.01 * |
Lower extremity numbness | 54.4 ± 34.9 | 28.1 ± 32.6 | <0.01 ** |
Lower extremity pain | 37.8 ± 33.6 | 21.4 ± 29.4 | 0.03 * |
CNR Grade | High OP Index (n = 25) | Moderate/Low OP Index (n = 211) | p-Value |
---|---|---|---|
Grade 1 | 2 (8%) | 70 (33.2%) | |
2 | 8 (32%) | 71 (33.6%) | |
3 | 12 (48%) | 56 (26.5%) | |
4 | 3 (12%) | 14 (6.6%) | |
0.03 * |
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Hirai, T.; Yoshii, T.; Hashimoto, J.; Ushio, S.; Mori, K.; Maki, S.; Katsumi, K.; Nagoshi, N.; Takeuchi, K.; Furuya, T.; et al. Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study). J. Clin. Med. 2022, 11, 3694. https://doi.org/10.3390/jcm11133694
Hirai T, Yoshii T, Hashimoto J, Ushio S, Mori K, Maki S, Katsumi K, Nagoshi N, Takeuchi K, Furuya T, et al. Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study). Journal of Clinical Medicine. 2022; 11(13):3694. https://doi.org/10.3390/jcm11133694
Chicago/Turabian StyleHirai, Takashi, Toshitaka Yoshii, Jun Hashimoto, Shuta Ushio, Kanji Mori, Satoshi Maki, Keiichi Katsumi, Narihito Nagoshi, Kazuhiro Takeuchi, Takeo Furuya, and et al. 2022. "Clinical Characteristics of Patients with Ossification of the Posterior Longitudinal Ligament and a High OP Index: A Multicenter Cross-Sectional Study (JOSL Study)" Journal of Clinical Medicine 11, no. 13: 3694. https://doi.org/10.3390/jcm11133694