The Effect of Bariatric Surgery on Circulating Levels of Monocyte Chemoattractant Protein-1: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Methods
2.1. Search Strategy
2.2. Study Selection
2.3. Data Extraction
2.4. Quality Assessment
2.5. Quantitative Data Synthesis
2.6. Meta-Regression
2.7. Subgroup Analysis
2.8. Publication Bias
3. Results
3.1. Quality Assessment of the Included Studies
3.2. Primary Outcome
Effect of Bariatric Surgery on MCP-1 Concentration
3.3. Secondary Outcomes
Meta-Regression
3.4. Subgroup Analyses
3.5. Publication Bias
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Catalán, V.; Gómez-Ambrosi, J.; Ramirez, B.; Rotellar, F.; Pastor, C.; Silva, C.; Rodríguez, A.; Gil, M.J.; Cienfuegos, J.A.; Frühbeck, G. Proinflammatory Cytokines in Obesity: Impact of Type 2 Diabetes Mellitus and Gastric Bypass. Obes. Surg. 2007, 17, 1464–1474. [Google Scholar] [CrossRef]
- Engin, A.B. Adipocyte-Macrophage Cross-Talk in Obesity. Obes. Lipotoxic. 2017, 960, 327–343. [Google Scholar] [CrossRef]
- Inoue, S.; Egashira, K.; Ni, W.; Kitamoto, S.; Usui, M.; Otani, K.; Ishibashi, M.; Hiasa, K.-I.; Nishida, K.-I.; Takeshita, A. Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Limits Progression and Destabilization of Established Atherosclerosis in Apolipoprotein E–Knockout Mice. Circulation 2002, 106, 2700–2706. [Google Scholar] [CrossRef] [PubMed]
- Bianconi, V.; Sahebkar, A.; Atkin, S.L.; Pirro, M. The regulation and importance of monocyte chemoattractant protein-1. Curr. Opin. Hematol. 2018, 25, 44–51. [Google Scholar] [CrossRef] [PubMed]
- Bachmayer, C.; Lammert, A.; Hasenberg, T.; Hammes, H.-P. Healthy Obese and Post Bariatric Patients—Metabolic and Vascular Patterns. Exp. Clin. Endocrinol. Diabetes 2013, 121, 483–487. [Google Scholar] [CrossRef] [PubMed]
- Sutanto, A.; Wungu, C.D.K.; Susilo, H.; Sutanto, H. Reduction of Major Adverse Cardiovascular Events (MACE) after Bariatric Surgery in Patients with Obesity and Cardiovascular Diseases: A Systematic Review and Meta-Analysis. Nutrients 2021, 13, 3568. [Google Scholar] [CrossRef] [PubMed]
- Tsilingiris, D.; Koliaki, C.; Kokkinos, A. Remission of type 2 diabetes mellitus after bariatric surgery: Fact or fiction? Int. J. Environ. Res. Public Health 2019, 16, 3171. [Google Scholar] [CrossRef] [Green Version]
- Jamialahmadi, T.; Alidadi, M.; Atkin, S.L.; Kroh, M.; Almahmeed, W.; Moallem, S.A.; Al-Rasadi, K.; Rodriguez, J.H.; Santos, R.D.; Ruscica, M.; et al. Effect of Bariatric Surgery on Flow-Mediated Vasodilation as a Measure of Endothelial Function: A Systematic Review and Meta-Analysis. J. Clin. Med. 2022, 11, 4054. [Google Scholar] [CrossRef] [PubMed]
- Jamialahmadi, T.; Reiner, Ž.; Alidadi, M.; Kroh, M.; Almahmeed, W.; Ruscica, M.; Sirtori, C.; Rizzo, M.; Santos, R.D.; Sahebkar, A. The Effect of Bariatric Surgery on Circulating Levels of Lipoprotein (a): A Meta-analysis. BioMed Res. Int. 2022, 2022, 8435133. [Google Scholar] [CrossRef]
- Jamialahmadi, T.; Reiner, Ž.; Alidadi, M.; Kroh, M.; Cardenia, V.; Xu, S.; Al-Rasadi, K.; Santos, R.D.; Sahebkar, A. The Effect of Bariatric Surgery on Circulating Levels of Oxidized Low-Density Lipoproteins Is Apparently Independent of Changes in Body Mass Index: A Systematic Review and Meta-Analysis. Oxidative Med. Cell. Longev. 2021, 2021, 4136071. [Google Scholar] [CrossRef]
- Jamialahmadi, T.; Reiner, Ž.; Alidadi, M.; Kroh, M.; Simental-Mendia, L.E.; Pirro, M.; Sahebkar, A. Impact of Bariatric Surgery on Pulse Wave Velocity as a Measure of Arterial Stiffness: A Systematic Review and Meta-analysis. Obes. Surg. 2021, 31, 4461–4469. [Google Scholar] [CrossRef]
- Nabavi, N.; Ghodsi, A.; Rostami, R.; Torshizian, A.; Jamialahmadi, T.; Jangjoo, A.; Nematy, M.; Bahari, A.; Ebrahimzadeh, F.; Mahmoudabadi, E.; et al. Impact of Bariatric Surgery on Carotid Intima-Media Thickness in Patients with Morbid Obesity: A Prospective Study and Review of the Literature. Obes. Surg. 2022, 32, 1563–1569. [Google Scholar] [CrossRef] [PubMed]
- Jamialahmadi, T.; Jangjoo, A.; Rezvani, R.; Goshayeshi, L.; Tasbandi, A.; Nooghabi, M.J.; Rajabzadeh, F.; Ghaffarzadegan, K.; Mishamandani, Z.J.; Nematy, M. Hepatic Function and Fibrosis Assessment via 2D-Shear Wave Elastography and Related Biochemical Markers Pre- and Post-Gastric Bypass Surgery. Obes. Surg. 2020, 30, 2251–2258. [Google Scholar] [CrossRef] [PubMed]
- Jamialahmadi, T.; Banach, M.; Almahmeed, W.; Kesharwani, P.; Sahebkar, A. Impact of bariatric surgery on circulating PCSK9 levels as marker of cardiovascular disease risk: A meta-analysis. Arch. Med. Sci. 2022, 18, 1372–1377. [Google Scholar] [CrossRef] [PubMed]
- Jamialahmadi, T.; Reiner, Ž.; Alidadi, M.; Almahmeed, W.; Kesharwani, P.; Al-Rasadi, K.; Eid, A.H.; Rizzo, M.; Sahebkar, A. Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis. J. Clin. Med. 2022, 11, 6056. [Google Scholar] [CrossRef] [PubMed]
- Coelho, C.; Crane, J.; Agius, R.; McGowan, B. The Bariatric-Metabolic Physician’s Role in Managing Clinically Severe Obesity. Curr. Obes. Rep. 2021, 10, 263–273. [Google Scholar] [CrossRef] [PubMed]
- Carmona-Maurici, J.; Cuello, E.; Ricart-Jané, D.; Miñarro, A.; Baena-Fustegueras, J.A.; Peinado-Onsurbe, J.; Pardina, E. Effect of bariatric surgery on inflammation and endothelial dysfunction as processes underlying subclinical atherosclerosis in morbid obesity. Surg. Obes. Relat. Dis. 2020, 16, 1961–1970. [Google Scholar] [CrossRef]
- Sutton, A.J.; Abrams, K.R.; Jones, D.R.; Jones, D.R.; Sheldon, T.A.; Song, F. Methods for Meta-Analysis in Medical Research; Wiley: Chichester, UK, 2000. [Google Scholar]
- Higgins, J.P.T.; Green, S. (Eds.) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [Updated March 2011]. The Cochrane Collaboration, 2011. Available online: www.handbook.cochrane.org (accessed on 26 November 2022).
- Wells, G.A.; Shea, B.; O’Connell Da Peterson, J.; Welch, V.; Losos, M.; Tugwell, P. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses. Oxford. 2000. Available online: https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp (accessed on 26 November 2022).
- Borenstein, M.; Hedges, L.; Higgins, J.; Rothstein, H. Comprehensive Meta-Analysis, Version 2; Biostat: Englewood, NJ, USA, 2005; Available online: https://www.meta-analysis.com/ (accessed on 26 November 2022).
- Banach, M.; Serban, C.; Ursoniu, S.; Rysz, J.; Muntner, P.; Toth, P.P.; Jones, S.R.; Rizzo, M.; Glasser, S.P.; Watts, G.F.; et al. Statin therapy and plasma coenzyme Q10 concentrations—A systematic review and meta-analysis of placebo-controlled trials. Pharmacol. Res. 2015, 99, 329–336. [Google Scholar] [CrossRef]
- Duval, S.; Tweedie, R. Trim and Fill: A Simple Funnel-Plot-Based Method of Testing and Adjusting for Publication Bias in Meta-Analysis. Biometrics 2000, 56, 455–463. [Google Scholar] [CrossRef]
- Salman, A.; Salman, M.; Sarhan, M.D.; Maurice, K.; El-Din, M.T.; Youssef, A.; Ahmed, R.; Abouelregal, T.; Shaaban, H.E.-D.; GabAllah, G.M.; et al. Changes of Urinary Cytokines in Non-Diabetic Obese Patients after Laparoscopic Sleeve Gastrectomy. Int. J. Gen. Med. 2021, 14, 825–831. [Google Scholar] [CrossRef]
- Rizk, N.M.; Fadel, A.; AlShammari, W.; Younes, N.; Bashah, M. The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects after Laparoscopic Gastric Sleeve Surgery—A Follow-Up Study. J. Inflamm. Res. 2021, 14, 1743–1757. [Google Scholar] [CrossRef] [PubMed]
- Morales, E.; Porrini, E.; Martin-Taboada, M.; Luis-Lima, S.; Vila-Bedmar, R.; de Pablos, I.G.; Gómez, P.; Rodríguez, E.; Torres, L.; Lanzón, B.; et al. Renoprotective role of bariatric surgery in patients with established chronic kidney disease. Clin. Kidney J. 2021, 14, 2037–2046. [Google Scholar] [CrossRef] [PubMed]
- Yan, Y.; Wang, F.; Chen, H.; Zhao, X.; Yin, D.; Hui, Y.; Wang, G. Efficacy of laparoscopic gastric bypassvslaparoscopic sleeve gastrectomy in treating obesity combined with type-2 diabetes. Br. J. Biomed. Sci. 2021, 78, 35–40. [Google Scholar] [CrossRef] [PubMed]
- Bratti, L.D.O.S.; Carmo, A.R.D.; Vilela, T.F.; Souza, L.C.; de Moraes, A.C.R.; Filippin-Monteiro, F.B. Bariatric surgery improves clinical outcomes and adiposity biomarkers but not inflammatory cytokines SAA and MCP-1 after a six-month follow-up. Scand. J. Clin. Lab. Investig. 2021, 81, 230–236. [Google Scholar] [CrossRef] [PubMed]
- Salman, M.A.; Abdallah, A.; Mikhail, H.M.S.; Abdelsalam, A.; Ibrahim, A.H.; Sultan, A.A.E.A.; El-Ghobary, M.; Ismail, A.A.M.; Abouelregal, T.E.; Omar, M.G.; et al. Long-term Impact of Mini-Gastric Bypass on Inflammatory Cytokines in Cohort of Morbidly Obese Patients: A Prospective Study. Obes. Surg. 2020, 30, 2338–2344. [Google Scholar] [CrossRef] [PubMed]
- Lambert, G.; Lima, M.M.D.O.; Felici, A.C.; Pareja, J.C.; Vasques, A.C.J.; Novaes, F.S.; Rodovalho, S.; Hirsch, F.F.P.; Matos-Souza, J.R.; Chaim, A.; et al. Early Regression of Carotid Intima-Media Thickness after Bariatric Surgery and Its Relation to Serum Leptin Reduction. Obes. Surg. 2018, 28, 226–233. [Google Scholar] [CrossRef] [PubMed]
- Alsharidah, M.; Alghamdi, F.; Aldosri, H.; Alharbi, A.; Alwarthan, A.; Bamihrez, F.; Alkhaldi, H.; Alsaif, F.; Hassanain, M. Assessment of liver inflammation and fibrosis after weight loss secondary to bariatric surgery in patients with nonalcoholic fatty liver disease. HPB 2018, 20, S444. [Google Scholar] [CrossRef] [Green Version]
- Yadav, R.; Hama, S.; Liu, Y.; Siahmansur, T.; Schofield, J.; Syed, A.A.; France, M.; Pemberton, P.; Adam, S.; Ho, J.H.; et al. Effect of Roux-en-Y Bariatric Surgery on Lipoproteins, Insulin Resistance, and Systemic and Vascular Inflammation in Obesity and Diabetes. Front. Immunol. 2017, 8, 1512. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- van der Wielen, N.; Paulus, G.; van Avesaat, M.; Masclee, A.; Meijerink, J.; Bouvy, N. Effect of Endoscopic Gastroplication on the Genome-Wide Transcriptome in the Upper Gastrointestinal Tract. Obes. Surg. 2017, 27, 740–748. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sams, V.G.; Blackledge, C.; Wijayatunga, N.; Barlow, P.; Mancini, M.; Mancini, G.; Moustaid-Moussa, N. Effect of bariatric surgery on systemic and adipose tissue inflammation. Surg. Endosc. 2016, 30, 3499–3504. [Google Scholar] [CrossRef] [PubMed]
- Kelly, A.S.; Ryder, J.R.; Marlatt, K.L.; Rudser, K.D.; Jenkins, T.; Inge, T.H. Changes in inflammation, oxidative stress and adipokines following bariatric surgery among adolescents with severe obesity. Int. J. Obes. 2016, 40, 275–280. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Immonen, H.; Hannukainen, J.C.; Iozzo, P.; Soinio, M.; Salminen, P.; Saunavaara, V.; Borra, R.; Parkkola, R.; Mari, A.; Lehtimäki, T.; et al. Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients. J. Hepatol. 2014, 60, 377–383. [Google Scholar] [CrossRef] [PubMed]
- Gumbau, V.; Bruna, M.; Canelles, E.; Guaita, M.; Mulas, C.; Basés, C.; Celma, I.; Puche, J.; Marcaida, G.; Oviedo, M.; et al. A Prospective Study on Inflammatory Parameters in Obese Patients After Sleeve Gastrectomy. Obes. Surg. 2014, 24, 903–908. [Google Scholar] [CrossRef] [PubMed]
- Thomsen, S.B.; Rathcke, C.N.; Jørgensen, N.B.; Madsbad, S.; Vestergaard, H. Effects of Roux-en-Y Gastric Bypass on Fasting and Postprandial Levels of the Inflammatory Markers YKL-40 and MCP-1 in Patients with Type 2 Diabetes and Glucose Tolerant Subjects. J. Obes. 2013, 2013, 361781. [Google Scholar] [CrossRef] [Green Version]
- Lima, M.M.O.; Pareja, J.C.; Alegre, S.M.; Geloneze, S.R.; Kahn, S.E.; Astiarraga, B.; Chaim, A.; Baracat, J.; Geloneze, B. Visceral fat resection in humans: Effect on insulin sensitivity, beta-cell function, adipokines, and inflammatory markers. Obesity 2013, 21, E182–E189. [Google Scholar] [CrossRef]
- Monte, S.V.; Caruana, J.A.; Ghanim, H.; Sia, C.L.; Korzeniewski, K.; Schentag, J.J.; Dandona, P. Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus. Surgery 2012, 151, 587–593. [Google Scholar] [CrossRef]
- Dalmas, E.; Rouault, C.; Abdennour, M.; Rovere, C.; Rizkalla, S.; Bar-Hen, A.; Nahon, J.-L.; Bouillot, J.-L.; Guerre-Millo, M.; Clément, K.; et al. Variations in circulating inflammatory factors are related to changes in calorie and carbohydrate intakes early in the course of surgery-induced weight reduction. Am. J. Clin. Nutr. 2011, 94, 450–458. [Google Scholar] [CrossRef] [Green Version]
- Schaller, G.; Aso, Y.; Schernthaner, G.; Kopp, H.-P.; Inukai, T.; Kriwanek, S.; Schernthaner, G. Increase of Osteopontin Plasma Concentrations After Bariatric Surgery Independent from Inflammation and Insulin Resistance. Obes. Surg. 2009, 19, 351–356. [Google Scholar] [CrossRef]
- Hempen, M.; Kopp, H.-P.; Elhenicky, M.; Höbaus, C.; Brix, J.-M.; Koppensteiner, R.; Schernthaner, G.; Schernthaner, G.-H. YKL-40 is Elevated in Morbidly Obese Patients and Declines After Weight Loss. Obes. Surg. 2009, 19, 1557–1563. [Google Scholar] [CrossRef]
- Swarbrick, M.M.; Stanhope, K.L.; Austrheim-Smith, I.T.; Van Loan, M.D.; Ali, M.R.; Wolfe, B.M.; Havel, P.J. Longitudinal changes in pancreatic and adipocyte hormones following Roux-en-Y gastric bypass surgery. Diabetologia 2008, 51, 1901–1911. [Google Scholar] [CrossRef]
- Fontana, L.; Eagon, J.C.; Colonna, M.; Klein, S. Impaired Mononuclear Cell Immune Function in Extreme Obesity Is Corrected by Weight Loss. Rejuvenation Res. 2007, 10, 41–46. [Google Scholar] [CrossRef] [Green Version]
- Schernthaner, G.; Kopp, H.-P.; Kriwanek, S.; Krzyzanowska, K.; Satler, M.; Koppensteiner, R.; Schernthaner, G. Effect of Massive Weight Loss induced by Bariatric Surgery on Serum Levels of Interleukin-18 and Monocyte-Chemoattractant-Protein-1 in Morbid Obesity. Obes. Surg. 2006, 16, 709–715. [Google Scholar] [CrossRef]
- Sartipy, P.; Loskutoff, D.J. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc. Natl. Acad. Sci. USA 2003, 100, 7265–7270. [Google Scholar] [CrossRef] [Green Version]
- Yuasa, S.; Maruyama, T.; Yamamoto, Y.; Hirose, H.; Kawai, T.; Matsunaga-Irie, S.; Itoh, H. MCP-1 gene A-2518G polymorphism and carotid artery atherosclerosis in patients with type 2 diabetes. Diabetes Res. Clin. Pract. 2009, 86, 193–198. [Google Scholar] [CrossRef]
- Makarewicz-Wujec, M.; Henzel, J.; Kępka, C.; Kruk, M.; Wardziak, Ł.; Trochimiuk, P.; Parzonko, A.; Dzielińska, Z.; Demkow, M.; Kozłowska-Wojciechowska, M. Usefulness of MCP-1 Chemokine in the Monitoring of Patients with Coronary Artery Disease Subjected to Intensive Dietary Intervention: A Pilot Study. Nutrients 2021, 13, 3047. [Google Scholar] [CrossRef] [PubMed]
- Christiansen, T.; Richelsen, B.; Bruun, J.M. Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects. Int. J. Obes. 2005, 29, 146–150. [Google Scholar] [CrossRef] [Green Version]
- Komorowski, J.; Jankiewicz-Wika, J.; Kolomecki, K.; Cywinski, J.; Piestrzeniewicz, K.; Swiętoslawski, J.; Stepien, H. Systemic blood osteopontin, endostatin, and E-selectin concentrations after vertical banding surgery in severely obese adults. Cytokine 2011, 55, 56–61. [Google Scholar] [CrossRef] [PubMed]
- Rothman, K.J. BMI-related errors in the measurement of obesity. Int. J. Obes. 2008, 32, S56–S59. [Google Scholar] [CrossRef] [Green Version]
- Seyyedi, J.; Alizadeh, S. Effect of Surgically Induced Weight Loss on Biomarkers of Endothelial Dysfunction: A Systematic Review and Meta-Analysis. Obes. Surg. 2020, 30, 3549–3560. [Google Scholar] [CrossRef] [PubMed]
- Sachan, A.; Singh, A.; Shukla, S.; Aggarwal, S.; Mir, I.; Yadav, R. An immediate post op and follow up assessment of circulating adipo-cytokines after bariatric surgery in morbid obesity. Metab. Open 2022, 13, 100147. [Google Scholar] [CrossRef]
- Villarreal-Calderon, J.R.; Cuellar-Tamez, R.; Castillo, E.C.; Luna-Ceron, E.; García-Rivas, G.; Elizondo-Montemayor, L. Metabolic shift precedes the resolution of inflammation in a cohort of patients undergoing bariatric and metabolic surgery. Sci. Rep. 2021, 11, 12127. [Google Scholar] [CrossRef] [PubMed]
Study, Year, Country | Study Design | Follow-Up | Type of Surgery | Clinical Outcome | Patients | No. of Patients | |
---|---|---|---|---|---|---|---|
MCP-1 Level Change | % BMI Change | ||||||
Salman 2021 [24] | Prospective study | 12 months | LSG | Unchanged | −10.22 kg/m2 | Obese non-diabetic patients | 61 |
Rizk 2021 [25] | Prospective longitudinal research | 3 months | LSG | Significant reduction | −15.96 kg/m2 | Class III obesity subjects | 24 |
Morales 2021 [26] | Prospective observational study | 12 months | LSG, also known as RYGB | Significant reduction | −14.20 kg/m2 | Obese patients with CKD | 30 |
Yan 2021 a [27] Yan 2021 b [27] | Prospective randomized study | 1 month 3 months 6 months 12 months | RYGB LSG | Significant reduction Significant reduction after 6, also known as 12 months | −8.30 kg/m2 (after 12 months) −8.80 kg/m2 (after 12 months) | Overweight and obese patients with BMI > 28 kg/m2 and type-2 diabetes | 77 80 |
Bratti 2021 [28] | Prospective study | 6 months | LSG, also known as RYGB | Unchanged | −15.47 kg/m2 | Severe obesity | 40 |
Salman 2020 [29] | Prospective study | 12 months | OAGB | Significant increase in MCP-1 level | −10.07 kg/m2 | Obese patients | 62 |
Lambert 2018 [30] | Prospective study | 1–2 months 12 months | BPD, also known as RYGB | Unchanged Significant reduction | −11.8 kg/m2 | Obese patients | 109 |
Alsharidah 2018 [31] | Prospective study | 3 months | Mixed | Significant reduction | −6.5 kg/m2 | Patients with NAFLD and obesity | 51 |
Yadav 2017 [32] | Prospective study | 6 months 12 months | RYGB | Significant reduction | −17 kg/m2 (after 12 months) | Obese patients | 37 |
van der Wielen 2017 [33] | Prospective study | 12 months | Gastroplication | Unchanged | −6.4 kg/m2 | Morbidly obese patients | 10 |
Sams 2016 a [34] Sams 2016 b [34] | Case-control study | 2 weeks 6 months 2 weeks 6 months | RYGB LAGB | Unchanged | −12.7 kg/m2 −4 kg/m2 | Obese patients | 8 2 |
Kelly 2016 a Kelly 2016 b [35] | Longitudinal cohorts Longitudinal cohorts | 6 months 12 months 6 months 12 months | LSG, also known as RYGB RYGB | Unchanged | −16.63 kg/m2 −20.9 kg/m2 | Obese adolescents | 39 13 |
Immonen 2014 a Immonen 2014 b [36] | Prospective study | 6 months 6 months | LSG, also known as RYGB | Unchanged | −10 kg/m2 −9.8 kg/m2 | Diabetic obese patients Non-diabetic obese patients | 9 14 |
Gumbau 2014 [37] | Prospective study | 1 day 5 days 1 month 6 months 12 months | LSG | Significant reduction after 12 months | −15.34 kg/m2 (after 12 months) | Morbidly obese | 20 |
Bachmayer 2013 [5] | Prospective observational study | 10 ± 6 months | Mixed | Unchanged | −13.4 kg/m2 | Obese patients | 21 |
Brinklov Thomsen 2013 a Brinklov Thomsen 2013 b [38] | Prospective cohort study | 1 week 3 months 12 months 1 week 3 months 12 months | RYGB | Significant reduction | −30.52 kg/m2 −29.86 kg/m2 | Obese patients without diabetes Obese patients with diabetes | 10 10 |
Lima 2013 [39] | Prospective study | 1 month 6 months 12 months | RYGB | Significant reduction | −16.4 kg/m2 | Premenopausal women with metabolic syndrome and grade III obesity | 10 |
Monte 2012 [40] | Prospective study | 6 months | RYGB | Significant reduction | −11.7 kg/m2 | Obese diabetic patients | 15 |
Dalmas 2011 [41] | Case-control study | 3 months 6 months 12 months | RYGB | Significant reduction after 3 and 12 months | −13.4 kg/m2 | Obese women | 51 |
Schaller 2009 [42] | Prospective observational study | 18 ± 3 months | RYGB, also known as LGB | Significant reduction | −13.1 kg/m2 | Morbidly obese patients | 31 |
Hempen 2009 [43] | Case-control study | 17.4 months | RYGB | Significant reduction | −13.2 kg/m2 | Obese patients | 17 |
Swarbrick 2008 [44] | Prospective study | 12 months | RYGB | Unchanged | −14.8 kg/m2 | Obese women | 19 |
Catalán 2007 [1] | Case-control study | 13 months | RYGB | Unchanged | −15.8 kg/m2 | Obese women | 14 |
Fontana 2007 [45] | Case-control study | 12 months | RYGB | Unchanged | −18.7 kg/m2 | Women with class III obesity | 6 |
Schernthaner 2006 [46] | Prospective study | 26.6 ± 11.5 months | VBG | Significant reduction | −12 kg/m2 | Obese patients | 37 |
Study | Selection | Comparability | Outcome | ||||||
---|---|---|---|---|---|---|---|---|---|
Representativeness of the Exposed Cohort | Selection of the Non-Exposed Cohort | Ascertainment of Exposure | Demonstration That Outcome of Interest Was Not Present at Start of Study | Comparability of Cohorts on the Basis of the Design or Analysis | Assessment of Outcome | Was Follow-Up Long Enough for Outcomes to Occur | Adequacy of Follow-Up of Cohorts | ||
Salman 2021 [24] | * | - | * | * | - | * | * | * | |
Rizk 2021 [25] | * | * | * | * | - | * | - | - | |
Morales 2021 [26] | * | - | * | * | - | * | * | * | |
Yan 2021 [27] | * | - | * | * | - | * | * | * | |
Bratti 2021 [28] | * | * | * | * | * | * | * | * | |
Salman 2020 [29] | * | - | * | * | - | * | * | * | |
Lambert 2018 [30] | * | * | * | * | * | * | * | * | |
Alsharidah 2018 [31] | * | - | * | * | - | * | - | - | |
Yadav 2017 [32] | * | - | * | * | - | * | * | * | |
van der Wielen 2017 [33] | * | - | * | * | - | * | * | * | |
Sams 2016 [34] | * | - | * | * | - | * | * | * | |
Kelly 2016 [35] | * | - | * | * | - | * | * | * | |
Immonen 2014 [36] | * | * | * | * | * | * | * | * | |
Gumbau 2014 [37] | * | - | * | * | - | * | * | * | |
Bachmayer 2013 [5] | * | - | * | * | - | * | * | * | |
Thomsen 2013 [38] | * | - | * | * | - | * | * | * | |
Monte 2012 [40] | * | - | * | * | - | * | * | * | |
Dalmas 2011 [41] | * | * | * | * | * | * | * | * | |
Schaller 2009 [42] | * | - | * | * | - | * | * | * | |
Hempen 2009 [43] | * | - | * | * | - | * | * | * | |
Swarbrick 2008 [44] | * | - | * | * | - | * | * | * | |
Catalán 2007 [1] | * | - | * | * | - | * | * | * | |
Fontana 2007 [45] | * | * | * | * | * | * | * | * | |
Schernthaner 2006 [46] | * | * | * | * | * | * | * | * | |
Selection bias | Performance bias | detection bias | attrition bias | Reporting bias | other bias | ||||
Random sequence generation | Allocation concealment | ||||||||
Lima 2013 [39] | Unclear | high | low | Unclear | low | low | low |
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Jamialahmadi, T.; Abbasifard, M.; Reiner, Ž.; Kesharwani, P.; Sahebkar, A. The Effect of Bariatric Surgery on Circulating Levels of Monocyte Chemoattractant Protein-1: A Systematic Review and Meta-Analysis. J. Clin. Med. 2022, 11, 7021. https://doi.org/10.3390/jcm11237021
Jamialahmadi T, Abbasifard M, Reiner Ž, Kesharwani P, Sahebkar A. The Effect of Bariatric Surgery on Circulating Levels of Monocyte Chemoattractant Protein-1: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2022; 11(23):7021. https://doi.org/10.3390/jcm11237021
Chicago/Turabian StyleJamialahmadi, Tannaz, Mitra Abbasifard, Željko Reiner, Prashant Kesharwani, and Amirhossein Sahebkar. 2022. "The Effect of Bariatric Surgery on Circulating Levels of Monocyte Chemoattractant Protein-1: A Systematic Review and Meta-Analysis" Journal of Clinical Medicine 11, no. 23: 7021. https://doi.org/10.3390/jcm11237021