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Review
Peer-Review Record

The Dilemma of the Level of the Inferior Mesenteric Artery Ligation in the Treatment of Diverticular Disease: A Systematic Review of the Literature

J. Clin. Med. 2022, 11(4), 917; https://doi.org/10.3390/jcm11040917
by Roberto Cirocchi 1, Giulio Mari 2,*, Bruno Amato 3, Giovanni Domenico Tebala 4, Georgi Popivanov 5, Stefano Avenia 1 and Riccardo Nascimbeni 6
Reviewer 1: Anonymous
Reviewer 2:
J. Clin. Med. 2022, 11(4), 917; https://doi.org/10.3390/jcm11040917
Submission received: 11 January 2022 / Revised: 1 February 2022 / Accepted: 4 February 2022 / Published: 10 February 2022
(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Round 1

Reviewer 1 Report

Paying attention to the following references can be useful

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                                Cirocchi R, Trastulli S, Farinella E, Desiderio J, Listorti C, Parisi A, Noya G, Boselli C

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Author Response

Thank you for the sharp and effective medline search suggested. We incorporated the article by  Jolivet M. et al. and by Campbell A et al in the discussion.

Reviewer 2 Report

The authors analyzed twelve studies comparing ligation of the Arteria mesenterica inferior (AMI) and AMI-preserving technique in sigmoidectomy for diverticular diseases with regard to functional outcomes (bowel function, urinary function and sexual function; primary endpoints) as well as further secondary endpoints.

They found no significant differences regarding the primary endpoints, but a significant longer procedure time and a significant higher conversion rate.

The study is well done and the results are well interpreted.

I would recommend to make some minor revisions:

- Please list the abbreviation "RS" in table 1.

- I would delete the figure 2a, figure 2b is quite sufficient.

- May the different techniques of AMI-preserving influence the conversion rate and the procedure time? Could you perform subgroup analyses due to the technique of IMA preservation?

Author Response

Thank you for the suggestion provided.

Table 1 was corrected accordingly.

We incorporated as new sub analysis (fig 9 and 11) the requested sub analysis on the different types of IMA preservation.

Figure 2.a was deleted

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