Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Protocol and Registration
2.2. Eligibility Criteria
2.3. Information Sources
2.4. Study Selection
2.5. Data Collection Process
2.6. Risk of Bias
2.7. Data Synthesis
2.8. Additional Analyses
3. Results
3.1. Study Selection
3.2. Study Characteristics
3.3. Critical Appraisal
3.4. Long-Term Mortality following MI in Overweight Patients Compared to Normal Weight
3.5. Long-Term Mortality Following MI in Obese and Morbidly Obese Patients Compared to Normal Weight
3.6. Long-Term Mortality following MI in Underweight Patients Compared to Normal Weight
3.7. Studies Not Included in Meta-Analysis
3.8. The Association between BMI and MI Recurrence on Hospital Readmission
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Study | Follow-up (months) | Females/ Males | Country | Exposure | Comparison | Outcome Assessed |
---|---|---|---|---|---|---|
Akin 2015 [27] | 12 | 205/ 685 | Germany | BMI > 30, 25–30 kg/m2 | BMI ≤ 24.9 kg/m2 | Mortality, recurrence |
Aronson 2010 [40] | 26 | 459/ 1698 | Israel | BMI ≥ 35, 30–34.9, 25–29.9, < 18.5 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Bucholz 2012 [14] | 12 | 2076/ 4283 | USA | BMI ≥ 35, 30–34.9, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Bucholz 2016 a [15] | 204 | 57,921/ 67,060 | USA | BMI ≥ 35, 30–34.9, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Bucholz 2016 b [16] | 204 | 29,258/ 28316 | USA | BMI < 18.5 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Colombo 2015 [28] (Diabetes) | 120 | 337/ 853 | Germany | BMI ≥ 30, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Colombo 2015 [28] (No diabetes) | 120 | 630/ 2234 | Germany | BMI > 30, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Fukuoka 2019 [32] | 12 | 454/ 1666 | Japan | BMI ≥ 25, <20 kg/m2 | BMI 20–24.9 kg/m2 | Mortality |
Hoit 1987 [17] | 12 | 433/ 1327 | USA | BMI > 30, BMI 25–30 kg/m2 | BMI < 25 kg/m2 | Mortality, recurrence |
Ikeda 2011 [30] | 60 | 21/ 100 | Japan | BMI ≥ 25 kg/m2 | BMI < 25 kg/m2 | Mortality, recurrence, readmission |
Jelavić 2016 [36] | 12 | 73/ 177 | Croatia | BMI ≥ 30, 25–29.9 kg/m2 | BMI < 25 kg/m2 | Mortality, recurrence, readmission |
Kang 2010 [33] | 12 | 928/ 2896 | South Korea | BMI ≥ 27.5, 23–27.5, <18.5 kg/m2 | BMI 18.5–23 kg/m2 | Mortality |
Kim 2019 [34] | 12 | 2547/ 8021 | South Korea | BMI ≥ 26, <22 kg/m2 | BMI 22–26 kg/m2 | Mortality, recurrence |
Kragelund 2005 [38] | 120 | 2172/ 4502 | Denmark | BMI ≥ 30, 25–29.9, <19 kg/m2 | BMI 20–25 kg/m2 | Mortality |
Li 2013 [37] | 12 | 1380 (total) | China | BMI ≥ 28.0, 25–28 kg/m2 | BMI 18.5–24 kg/m2 | Mortality, recurrence, readmission |
Lopez-Jimenez 2008 [18] | 6.2 | 1022/ 1296 | USA | BMI ≥ 30, 25–29.9, < 19 kg/m2 | BMI 20–25 kg/m2 | Mortality, recurrence |
Mehta 2007 [19] | 12 | 606/ 1719 | USA | BM ≥ 30 kg/m2 | BMI < 25 kg/m2 | Mortality |
Neeland 2017 [20] | 36 | 7397/ 12102 | USA | BMI ≥ 40, 35–39.9, 30–34.9, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Nigam 2006 [21] | 12 | 278/ 616 | USA | BMI ≥ 30 kg/m2 | BMI < 25 kg/m2 | Mortality, recurrence |
Nikolsky 2006 [22] | 12 | 542/ 1493 | USA | BMI ≥ 30, 25–30 kg/m2 | BMI < 25 kg/m2 | Mortality |
O’Brien 2014 [23] | 36 | 16,351/ 18,114 | USA | BMI ≥ 40, 35–39.9, 30–34.9, 25–29.9, < 18.5 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality, readmission |
Rana 2004 [24] | 45 | 1317/ 581 | USA | BMI ≥ 30, 25–29.9 kg/m2 | BMI 20–25 kg/m2 | Mortality |
Rea 2001 [25] | 36 | 968/ 1573 | USA | BMI ≥ 30 kg/m2 | BMI < 25 kg/m2 | Recurrence |
Samanta 2020 [35] | 12 | 77/ 399 | Australia | BMI > 30, 25–29.99 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality, recurrence |
Wienbergen 2008 [29] | 14 | 3137/ 7397 | Germany | BMI ≥ 30, 25–29.9 kg/m2 | BMI 18.5–24.9 kg/m2 | Mortality |
Wu 2010 [26] | 16 | 1885/ 4675 | USA | BMI ≥ 30, 25–29.9 kg/m2 | BMI < 25 kg/m2 | Mortality |
Yokoyama 2019 [31] | 32.4 | 112/ 405 | Japan | BMI ≥ 26.0, ≥24- < 26, <21.9 kg/m2 | BMI ≥ 21.9- <24 kg/m2 | Mortality |
Zeller 2008 [39] | 12 | 593/ 1636 | France | BMI ≥ 30, 25–29.9 kg/m2 | BMI < 25 kg/m2 | Mortality |
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De Paola, L.; Mehta, A.; Pana, T.A.; Carter, B.; Soiza, R.L.; Kafri, M.W.; Potter, J.F.; Mamas, M.A.; Myint, P.K. Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis. J. Clin. Med. 2022, 11, 2581. https://doi.org/10.3390/jcm11092581
De Paola L, Mehta A, Pana TA, Carter B, Soiza RL, Kafri MW, Potter JF, Mamas MA, Myint PK. Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis. Journal of Clinical Medicine. 2022; 11(9):2581. https://doi.org/10.3390/jcm11092581
Chicago/Turabian StyleDe Paola, Lorenzo, Arnav Mehta, Tiberiu A. Pana, Ben Carter, Roy L. Soiza, Mohannad W. Kafri, John F. Potter, Mamas A. Mamas, and Phyo K. Myint. 2022. "Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction: Systematic Review and Meta-Analysis" Journal of Clinical Medicine 11, no. 9: 2581. https://doi.org/10.3390/jcm11092581