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Volume 12
Issue 16
10.3390/jcm12165221
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Article
Peer-Review Record

Characteristics, Treatment Strategies and Outcome in Cardiogenic Shock Complicating Acute Myocardial Infarction: A Contemporary Dutch Cohort

J. Clin. Med. 2023, 12(16), 5221; https://doi.org/10.3390/jcm12165221
by Elma J. Peters 1, Sanne ten Berg 1, Margriet Bogerd 1, Marijke J. C. Timmermans 2, Adriaan O. Kraaijeveld 3, Jeroen J. H. Bunge 4,5, Koen Teeuwen 6, Erik Lipsic 7, Krischan D. Sjauw 8, Robert-Jan M. van Geuns 9, Admir Dedic 10, Eric A. Dubois 4,5, Martijn Meuwissen 11, Peter Danse 12, Niels J. W. Verouden 1, Gabe Bleeker 13, José M. Montero Cabezas 14, Irlando A. Ferreira 15, Annemarie E. Engström 16, Wim K. Lagrand 16, Luuk C. Otterspoor 5,17, Alexander P. J. Vlaar 16, José P. S. Henriques 1,* and on behalf of the Participating Centers of the PCI Registration Committee of the Netherlands Heart Registrationadd Show full author list remove Hide full author list
Reviewer 1: Anonymous
Reviewer 2:
Tetsuya Ishikawa
J. Clin. Med. 2023, 12(16), 5221; https://doi.org/10.3390/jcm12165221
Submission received: 30 June 2023 / Revised: 3 August 2023 / Accepted: 8 August 2023 / Published: 10 August 2023
(This article belongs to the Special Issue Clinical Management of Cardiogenic Shock and Cardiac Arrest)

Round 1

Reviewer 1 Report

The data is relevant to a Dutch population and similar to other studies with some unique results. I would encourage including patient status consistent with the SCAI Shock scale. This scale have become frequently used to scale patient outcomes. 

In addition, studies have shown that out of hospital cardiac arrest is a major predictor for poor outcomes which seems less in your population. It might be worth assessing differences to other reports for this variation. 

There is no information on Left ventricular function which might be a part of the worse prognosis in NSTEM CS as other studies have suggested worse baseline LV function and more diffuse CAD.

Adding information on bleeding risk would be of interest as well.

In summary, this is a useful database but the information could be enhanced by greater comparisons to other study populations.

Author Response

Please see the attachment. 

Author Response File: Author Response.pdf

Reviewer 2 Report

The authors examined the details of 2000 patients with CS in the data of national database. Although there were limitations in the database, this is a mega-study. However, what is the new findings of this study? How can the readers get a new finding from this paper? Please, highlight a novel finding from this large cohort.  

Author Response

Please see attachment. 

 

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

The authors clearly mentioned about the significance of the study. The number of enrolled cohort and the up-dataness were reliable.

Author Response

Please see the attachment. 

Author Response File: Author Response.pdf

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