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Review

Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview

by
Jakub Włodarczyk
1,2,
Jacek Burzyński
1,
Bartłomiej Czerwiński
1,
Mateusz Prusisz
1,
Katarzyna Socała
3,
Ewa Poleszak
4,
Jakub Fichna
2,
Kasper Maryńczak
1,
Marcin Włodarczyk
1,* and
Łukasz Dziki
1
1
Department of General and Oncological, Medical University of Lodz, Pomorska 251, 90-213 Lodz, Poland
2
Department of Biochemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland
3
Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland
4
Chair and Department of Applied and Social Pharmacy, Medical University of Lublin, Chodźki 1, 20-093 Lublin, Poland
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2023, 12(2), 526; https://doi.org/10.3390/jcm12020526
Submission received: 7 December 2022 / Revised: 29 December 2022 / Accepted: 4 January 2023 / Published: 9 January 2023
(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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Abstract

Crohn’s disease (CD) is a subtype of chronic inflammatory bowel diseases (IBD) with characteristic skip lesions and transmural inflammation that may affect the entire gastrointestinal tract from the mouth to the anus. Persistent pain is one of the main symptoms of CD. This pain has multifactorial pathogenesis, but most often arises from intestinal inflammation itself, as well as from gut distention or partial intestinal obstruction. Some current evidence also suggests sensitization of sensory pathways, as well as modulation of those signals by the central nervous system, which highlights the impact of biopsychosocial factors. To date, most studies have focused only on the pain located in the abdomen, while pelvic pain has rarely been explored, despite it being a common symptom. The aim of this study is to provide an abbreviated summary of the current state of knowledge on the origins and treatment of pelvic pain in CD.
Keywords: Crohn’s disease; pelvic pain; pain treatment; pelvic manifestations of Crohn’s disease Crohn’s disease; pelvic pain; pain treatment; pelvic manifestations of Crohn’s disease

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MDPI and ACS Style

Włodarczyk, J.; Burzyński, J.; Czerwiński, B.; Prusisz, M.; Socała, K.; Poleszak, E.; Fichna, J.; Maryńczak, K.; Włodarczyk, M.; Dziki, Ł. Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview. J. Clin. Med. 2023, 12, 526. https://doi.org/10.3390/jcm12020526

AMA Style

Włodarczyk J, Burzyński J, Czerwiński B, Prusisz M, Socała K, Poleszak E, Fichna J, Maryńczak K, Włodarczyk M, Dziki Ł. Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview. Journal of Clinical Medicine. 2023; 12(2):526. https://doi.org/10.3390/jcm12020526

Chicago/Turabian Style

Włodarczyk, Jakub, Jacek Burzyński, Bartłomiej Czerwiński, Mateusz Prusisz, Katarzyna Socała, Ewa Poleszak, Jakub Fichna, Kasper Maryńczak, Marcin Włodarczyk, and Łukasz Dziki. 2023. "Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview" Journal of Clinical Medicine 12, no. 2: 526. https://doi.org/10.3390/jcm12020526

APA Style

Włodarczyk, J., Burzyński, J., Czerwiński, B., Prusisz, M., Socała, K., Poleszak, E., Fichna, J., Maryńczak, K., Włodarczyk, M., & Dziki, Ł. (2023). Management of Pelvic Pain in Patients with Crohn’s Disease—Current Overview. Journal of Clinical Medicine, 12(2), 526. https://doi.org/10.3390/jcm12020526

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