Laparoscopic Sleeve Gastrectomy versus Laparoscopic Roux-en-Y Gastric Bypass: An Analysis of Weight Loss Using a Multilevel Mixed-Effects Linear Model
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Surgical Technique
2.3. Data Collection
2.4. Statistical Analyses
3. Results
3.1. Demographic and Clinical Characteristics
3.2. Weight Loss
3.2.1. Two Years %TWL
3.2.2. Weight Loss Curve
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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LRYGB | LSG | ||||
---|---|---|---|---|---|
(n = 266) | (n = 169) | ||||
Variables | p Values | ||||
Sex | <0.001 | ||||
Female | 227 | 85.3% | 117 | 69.2% | |
Male | 39 | 14.7% | 52 | 30.8% | |
Age | 0.382 | ||||
Continuous (years), mean ± SD | 266 | 43.4 ± 0.7 | 169 | 42.5 ± 0.9 | |
Preoperative bodyweight | <0.001 | ||||
Continuous (kg), mean ± SD | 266 | 110.1 ± 0.9 | 169 | 123.6 ± 1.8 | |
Preoperative excess weight | <0.001 | ||||
Continuous (kg) mean ± SD | 266 | 45.3 ± 0.7 | 169 | 56.1 ± 1.6 | |
Preoperative BMI | <0.001 | ||||
Continuous (kg/m2) mean ± SD | 266 | 40.5 ± 0.2 | 169 | 44.0 ± 0.6 | |
ASA score | 0.01 | ||||
2 | 222 | 83.4% | 116 | 68.7% | |
3 | 44 | 16.6% | 53 | 31.3 | |
Former smokers | 0.534 | ||||
Yes | 42 | 15.8% | 23 | 13.6% | |
No | 224 | 84.2% | 146 | 86.4% | |
Diabetes | 0.521 | ||||
Yes | 67 | 25.2% | 38 | 22.5% | |
No | 199 | 74.8% | 131 | 77.5% | |
Hypertension | 0.447 | ||||
Yes | 82 | 30.8% | 58 | 34.3% | |
No | 184 | 69.2% | 111 | 65.7% | |
Dyslipidaemia | 0.485 | ||||
Yes | 69 | 25.9% | 49 | 29.0% | |
No | 197 | 74.1% | 120 | 71.0% | |
Sleep apnoea | 0.184 | ||||
Yes | 118 | 44.4% | 86 | 50.9% | |
No | 148 | 55.6% | 83 | 49.1% | |
Length of hospital stay (days) | 266 | 3.4 ± 0.1 | 169 | 3.0 ± 0.1 | 0.026 |
(n = 435) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
n | Percentage | Univariable Analysis | Multivariable Analysis * | |||||||
Variables | β ** | 95% CI | p Values | β ** | 95% CI | p Values | ||||
Sex | ||||||||||
Female | 1240 | 77.5% | Ref | <0.001 | Ref | 0.325 | ||||
Male | 359 | 22.5% | −5.46 | −7.49 | −3.42 | −0.89 | −2.65 | 0.88 | ||
Surgery age | ||||||||||
Continuous | 1599 | 100% | −0.29 | −0.36 | −0.22 | <0.001 | −0.15 | −0.21 | −0.09 | <0.001 |
Surgery BMI | ||||||||||
Continuous | 1599 | 100% | −1.3 | −1.55 | −1.05 | <0.001 | −1.17 | −1.35 | −0.98 | <0.001 |
Type of surgery | ||||||||||
LRYGB | 1069 | 66.8% | Ref | <0.001 | Ref | <0.001 | ||||
LSG | 530 | 33.2% | −10.80 | −12.56 | −9.03 | −6.67 | −8.33 | −5.00 | ||
Year of surgery | ||||||||||
Continuous | 1599 | 100% | −0.51 | −0.81 | −0.21 | <0.001 | 0.48 | 0.21 | 0.74 | <0.001 |
Time since surgery | ||||||||||
Continuous | 1599 | 100% | 0.78 | 0.75 | 0.81 | <0.001 | 0.78 | 0.75 | 0.82 | <0.001 |
Former smokers | ||||||||||
No | 1368 | 85.5% | Ref | 0.017 | Ref | 0.003 | ||||
Yes | 231 | 14.5% | 2.97 | 0.52 | 5.41 | 3.14 | 1.06 | 5.20 | ||
Diabetes | ||||||||||
No | 1197 | 74.9% | Ref | <0.001 | Ref | 0.003 | ||||
Yes | 409 | 25.1% | −4.81 | −6.73 | −2.90 | −2.63 | −4.37 | −0.88 | ||
Hypertension | ||||||||||
No | 1032 | 64.5% | Ref | <0.001 | ||||||
Yes | 567 | 35.5% | −6.15 | −7.88 | −4.41 | |||||
Dyslipidaemia | ||||||||||
No | 1268 | 79.3% | Ref | <0.001 | ||||||
Yes | 331 | 20.7% | −4.51 | −6.61 | −2.40 | |||||
Sleep apnoea | ||||||||||
No | 999 | 62.5% | Ref | <0.001 | ||||||
Yes | 600 | 37.5% | −6.59 | −8.31 | −4.87 | |||||
Individual variance |
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Pouchucq, C.; Dejardin, O.; Bouvier, V.; Lee Bion, A.; Savey, V.; Launoy, G.; Menahem, B.; Alves, A. Laparoscopic Sleeve Gastrectomy versus Laparoscopic Roux-en-Y Gastric Bypass: An Analysis of Weight Loss Using a Multilevel Mixed-Effects Linear Model. J. Clin. Med. 2023, 12, 2132. https://doi.org/10.3390/jcm12062132
Pouchucq C, Dejardin O, Bouvier V, Lee Bion A, Savey V, Launoy G, Menahem B, Alves A. Laparoscopic Sleeve Gastrectomy versus Laparoscopic Roux-en-Y Gastric Bypass: An Analysis of Weight Loss Using a Multilevel Mixed-Effects Linear Model. Journal of Clinical Medicine. 2023; 12(6):2132. https://doi.org/10.3390/jcm12062132
Chicago/Turabian StylePouchucq, Camille, Olivier Dejardin, Véronique Bouvier, Adrien Lee Bion, Véronique Savey, Guy Launoy, Benjamin Menahem, and Arnaud Alves. 2023. "Laparoscopic Sleeve Gastrectomy versus Laparoscopic Roux-en-Y Gastric Bypass: An Analysis of Weight Loss Using a Multilevel Mixed-Effects Linear Model" Journal of Clinical Medicine 12, no. 6: 2132. https://doi.org/10.3390/jcm12062132
APA StylePouchucq, C., Dejardin, O., Bouvier, V., Lee Bion, A., Savey, V., Launoy, G., Menahem, B., & Alves, A. (2023). Laparoscopic Sleeve Gastrectomy versus Laparoscopic Roux-en-Y Gastric Bypass: An Analysis of Weight Loss Using a Multilevel Mixed-Effects Linear Model. Journal of Clinical Medicine, 12(6), 2132. https://doi.org/10.3390/jcm12062132