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Open AccessArticle
Predictive Factors for Altered Quality of Life in Patients with Type 2 Diabetes Mellitus
by
Oana Albai
Oana Albai 1,2,3,
Adina Braha
Adina Braha 1,2,*
,
Bogdan Timar
Bogdan Timar 1,2,3
and
Romulus Timar
Romulus Timar 1,2,3
1
Department of Second Internal Medicine—Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
2
Department of Diabetes, Nutrition and Metabolic Diseases Clinic, “Pius Brînzeu” Emergency Clinical County University Hospital, 300723 Timisoara, Romania
3
Centre for Molecular Research in Nephrology and Vascular Disease/MOL-NEPHRO-VASC, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(15), 4389; https://doi.org/10.3390/jcm13154389 (registering DOI)
Submission received: 1 July 2024
/
Revised: 23 July 2024
/
Accepted: 25 July 2024
/
Published: 26 July 2024
Abstract
Objectives: To evaluate the quality of life (QoL) in a group of patients with type 2 diabetes (T2DM) and to identify predictive factors to apply the necessary measures to improve it. Methods: For this, 299 patients with T2DM were enrolled in a cross-sectional study, and their QoL was assessed using the EQ-5D-3L questionnaire. All patients underwent clinical exams, routine laboratory tests, and nerve conduction velocity (NCV) at the common peroneal nerve. Results: Patients had a median age of 66 (57; 70) years, median duration of T2DM of 10 (6; 15) years, median HbA1c of 8 (7; 9.3)%, and mean EQ-5D-3L score of 55%. In addition, 9.7% presented extreme difficulty in mobility, 18.5% severe difficulty in self-care, and 16.4% in usual activities. One-third presented with severe pain or discomfort, anxiety, or depression (level 3 EQ-5D-3L). DPN, heart failure (HF), cerebral stroke, and insulin therapy increased the likelihood of a reduced QoL (EQ-5D-3L < 50). The EQ-5D-3L score inversely correlated with serum creatinine, glycemic control, lipid profile, diabetes duration, age, mobility, self-care, pain/discomfort, usual activities, and anxiety/depression and positively correlated with NCV, HDLc, and eGFR. Conclusions: Preventing neuropathic complications, chronic kidney disease, stroke, and HF and obtaining the glycemic and lipid targets could improve the QoL in patients with T2DM.
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MDPI and ACS Style
Albai, O.; Braha, A.; Timar, B.; Timar, R.
Predictive Factors for Altered Quality of Life in Patients with Type 2 Diabetes Mellitus. J. Clin. Med. 2024, 13, 4389.
https://doi.org/10.3390/jcm13154389
AMA Style
Albai O, Braha A, Timar B, Timar R.
Predictive Factors for Altered Quality of Life in Patients with Type 2 Diabetes Mellitus. Journal of Clinical Medicine. 2024; 13(15):4389.
https://doi.org/10.3390/jcm13154389
Chicago/Turabian Style
Albai, Oana, Adina Braha, Bogdan Timar, and Romulus Timar.
2024. "Predictive Factors for Altered Quality of Life in Patients with Type 2 Diabetes Mellitus" Journal of Clinical Medicine 13, no. 15: 4389.
https://doi.org/10.3390/jcm13154389
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