Long-Term Follow-Up Regarding Pain Relief, Fertility, and Re-Operation after Surgery for Deep Endometriosis
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Study Cohort
3.2. Patients’ Characteristics
3.3. Clinical Symptoms
3.4. Surgical and Medical Treatment
3.5. Complementary Therapies
3.6. Fertility
3.7. Re-Operations
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
Appendix B
VARIABLES | |
---|---|
Patients’ characteristics | |
Age at index surgery, years a | 35.0 (6.4) [16.7–49.5] |
Body mass index (BMI) at index surgery, kg/m2 a | 23.5 (3.8) [17.7–36.8] |
Follow-up time, years b | 6.9 [6.3; 8.1] |
Complaints | |
Complaints at the time of answering the questionnaire, n | |
Yes | 72 (55.4%) |
No | 58 (44.6%) |
Change of complaints after the index surgery, n | |
Better | 107 (87.0%) |
Same | 13 (10.6%) |
Worse | 3 (2.4%) |
Medical treatment | |
Medication intake for recurrence prophylaxis after index surgery, n | |
Yes | 86 (66.7%) |
No | 43 (33.3%) |
Side effects due to medication intake, n | |
Yes | 48 (57.8%) |
No | 35 (42.2%) |
Discontinuation of medication intake due to side effects, n | |
Yes | 27 (57.4%) |
No | 20 (42.6%) |
Complementary therapies | |
Specific pain therapy after index surgery, n | |
Yes | 14 (10.7%) |
No | 117 (89.3%) |
Additional therapies (yoga, psychotherapy etc.), n | |
Yes | 48 (36.6%) |
No | 83 (63.4%) |
Rehabilitation, n | |
Yes | 37 (28.5%) |
No | 93 (71.5%) |
Fertility | |
Index surgery due to unfulfilled desire to have a child, n | |
Yes | 41 (31.8%) |
No | 88 (68.2%) |
Try to become pregnant after index surgery, n | |
Yes | 66 (52.0%) |
No | 61 (48.0%) |
Childbirth after index surgery, n | |
Yes | 37 (57.8%) |
No | 27 (42.2%) |
Time to first childbirth after index surgery, years c | 1.5 [0.8–6.7] |
Use of fertility treatment, n | |
Yes | 39 (60.0%) |
No | 26 (40.0%) |
Re-operations | |
Need for re-operation due to endometriosis-typical complaints, n | |
Yes | 44 (34.1%) |
No | 85 (65.9%) |
Time to first re-operation after index surgery, years c | 2.1 [0.2–10.9] |
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Drechsel-Grau, A.; Grube, M.; Neis, F.; Schoenfisch, B.; Kommoss, S.; Rall, K.; Brucker, S.Y.; Kraemer, B.; Andress, J. Long-Term Follow-Up Regarding Pain Relief, Fertility, and Re-Operation after Surgery for Deep Endometriosis. J. Clin. Med. 2024, 13, 5039. https://doi.org/10.3390/jcm13175039
Drechsel-Grau A, Grube M, Neis F, Schoenfisch B, Kommoss S, Rall K, Brucker SY, Kraemer B, Andress J. Long-Term Follow-Up Regarding Pain Relief, Fertility, and Re-Operation after Surgery for Deep Endometriosis. Journal of Clinical Medicine. 2024; 13(17):5039. https://doi.org/10.3390/jcm13175039
Chicago/Turabian StyleDrechsel-Grau, Alexander, Marcel Grube, Felix Neis, Birgitt Schoenfisch, Stefan Kommoss, Katharina Rall, Sara Y. Brucker, Bernhard Kraemer, and Juergen Andress. 2024. "Long-Term Follow-Up Regarding Pain Relief, Fertility, and Re-Operation after Surgery for Deep Endometriosis" Journal of Clinical Medicine 13, no. 17: 5039. https://doi.org/10.3390/jcm13175039