Transitions and Long-Term Clinical Outcomes in Patients Admitted in Intensive Care Units Receiving Continuous Renal Replacement Therapy
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Patient Description
3.2. CRRT Transitions and Renal and Patient Outcomes
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Heart Failure | Cardiac Surgery | Other Surgeries | Sepsis | Miscellanea | Total | p Value | |
---|---|---|---|---|---|---|---|
N | 20 | 20 | 11 | 14 | 15 | 80 | |
Men (%) | 95.0 | 55.0 | 63.3 | 64.3 | 80.0 | 72.5 | 0.05 |
Age (year) | 62.7(15.5) | 69.1 (9.8) | 65.3 (12.1) | 66.0 (13.7) | 62.9 (16.7) | 65.3 (13.6) | 0.6 |
Charlson index | 7 (3.4) | 5.5 (1.9) | 8.2 (4.0) | 5.4 (2.5) | 6.7 (3.4) | 6.4 (3.1) | 0.09 |
Previous CKD (%) | 40.0 | 20.0 | 27.3 | 23.1 | 26.7 | 27.8 | 0.7 |
DM (%) | 55.6 | 11.1 | 36.4 | 28.6 | 28.6 | 32.0 | 0.08 |
Ischemic heart disease (%) | 40.0 | 31.6 | 27.3 | 14.4 | 13.3 | 26.6 | 0.3 |
Reduced LVEF (<50%) (%) | 42.1 | 17.6 | 30.0 | 12.5 | 16.7 | 25.8 | 0.4 |
Diastolic dysfunction (%) | 16.7 | 11.8 | 0.0 | 0.0 | 8.3 | 9.5 | 0.8 |
Previous H failure (%) | 65.0 | 85.0 | 45.5 | 78.6 | 53.3 | 67.5 | 0.1 |
Stroke or TIA (%) | 10.0 | 20.0 | 18.2 | 0.0 | 13.3 | 12.5 | 0.5 |
Liver disease (%) | 15.0 | 10.0 | 54.5 | 28.6 | 40.0 | 26.2 | 0.04 |
Previous neoplasia (%) | 25.0 | 15.0 | 45.5 | 28.6 | 33.3 | 27.5 | 0.5 |
COPD (%) | 40.0 | 20.0 | 36.4 | 14.3 | 26.7 | 27.5 | 0.4 |
Exitus/CRRT output (%) | 40.0 | 15.0 | 54.2 | 21.4 | 40.0 | 32.5 | 0.4 |
Exitus by 1 year (%) | 85.0 | 45.0 | 81.8 | 42.9 | 53.3 | 61.3 | 0.4 |
Heart Failure | Cardiac Surgery | Other Surgeries | Sepsis | Miscellanea | Total | p Value | |
---|---|---|---|---|---|---|---|
Etiology | 0.06 | ||||||
Prerenal AKI (%) | 60.0 | 35.0 | 27.3 | 35.7 | 73.3 | 47.5 | |
ATN (%) | 40.0 | 65.0 | 72.7 | 64.3 | 26.7 | 52.5 | |
Laboratory data | |||||||
sCr (mg/dL) | 2.5 (1.6) | 2.0 (1.1) | 2.1 (0.9) | 2.1 (1.4) | 3.1 (1.4) | 2.3 (1.3) | 0.1 |
sUr (mg/dL) | 137.3 (66.8) | 113.2 (67.3) | 104.8 (60.7) | 115.5 (46.3) | 143.2 (77.4) | 123.8 (65.6) | 0.45 |
Bicarbonate (mmol/L) | 21.6 (4.3) | 25.7 (4.2) | 22.5 (2.6) | 24.3 (5.8) | 19.7 (6.5) | 22.9 (5.2) | 0.006 |
Lactate (mmol/L) | 1.4 [1–4] | 1.1 [0.8–1.6] | 1.6 [1.3–1.9] | 1.4 [1.1–2.4] | 2.2 [1.3–6.8] | 1.4 [1–3] | 0.8 |
Diuresis (ml/h) | 4.6 (10.0) | 7.2 (17.1) | 13.8 (34.1) | 38.8 (73.4) | 0.9 (2.6) | 11.8 (36.0) | 0.002 |
ECMO (%) | 20.0 | 15.6 | 18.1 | 0.0 | 1.0 | 12.7 | 0.4 |
VAS (%) | 85.0 | 90.0 | 81.8 | 78.6 | 73.3 | 82.5 | 0.8 |
CRRT modality | 0.3 | ||||||
CVVHDF (%) | 85.0 | 75.0 | 81.4 | 85.7 | 100.0 | 85.0 | |
CVVHF (%) | 0.0 | 10.0 | 0.0 | 14.3 | 0.0 | 5.1 | |
SCUF (%) | 15.0 | 15.0 | 18.2 | 0.0 | 0.0 | 10.0 |
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Valdenebro, M.; Portoles, J.; Serrano Salazar, M.L.; Muñoz Sánchez, A.; Alameda-Aguado, I.; Martín Rodriguez, L.; Zalamea-Jarrin, F.; López-Sánchez, P. Transitions and Long-Term Clinical Outcomes in Patients Admitted in Intensive Care Units Receiving Continuous Renal Replacement Therapy. J. Clin. Med. 2024, 13, 5085. https://doi.org/10.3390/jcm13175085
Valdenebro M, Portoles J, Serrano Salazar ML, Muñoz Sánchez A, Alameda-Aguado I, Martín Rodriguez L, Zalamea-Jarrin F, López-Sánchez P. Transitions and Long-Term Clinical Outcomes in Patients Admitted in Intensive Care Units Receiving Continuous Renal Replacement Therapy. Journal of Clinical Medicine. 2024; 13(17):5085. https://doi.org/10.3390/jcm13175085
Chicago/Turabian StyleValdenebro, María, Jose Portoles, María Luisa Serrano Salazar, Ana Muñoz Sánchez, Ines Alameda-Aguado, Leyre Martín Rodriguez, Felipe Zalamea-Jarrin, and Paula López-Sánchez. 2024. "Transitions and Long-Term Clinical Outcomes in Patients Admitted in Intensive Care Units Receiving Continuous Renal Replacement Therapy" Journal of Clinical Medicine 13, no. 17: 5085. https://doi.org/10.3390/jcm13175085