Quadruple Assessment of Colorectal Anastomosis after Laparoscopic Rectal Resection: A Retrospective Analysis of a Propensity-Matched Cohort
Abstract
:1. Introduction
2. Materials and Methods
3. Statistical Analysis
4. Results
5. Discussion
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Total n = 293 | Quadruple Control Group n = 143 | Control Group n = 150 | p | |
---|---|---|---|---|
Mean age (±SD) | 68.5 (±11.5) | 65.17 (±13.25) | 68.50 (±10.25) | 0.84 |
Gender, % | 0.07 | |||
Male | 113 (38.5) | 51 (35.6) | 62 (43.4) | |
Female | 180 (61.5) | 92 (64.4) | 88 (56.6) | |
ASA score, % | 0.49 | |||
1/2 | 157 (54.2) | 75 (52.4) | 82 (55.1) | |
3/4 | 136 (45.8) | 68 (47.6) | 68 (44.9) | |
BMI (Kg/m2), mean (±SD) | 25.4 (±4.08) | 25.81 (±4.19) | 25.16 (±2.99) | 0.52 |
Comorbidity, % | 201 (68.6) | 98 (68.5) | 103 (68.6) | 0.58 |
Tumour distance from AV | 0.56 | |||
>10 cm | 138 (47.1) | 63 (45.7) | 75 (49.5) | |
5.1–10 cm | 92 (31.4) | 49 (34.4) | 43 (29) | |
<5 cm | 63 (21.5) | 31 (21.5) | 32 (21.2) | |
nCRT, % | 145 (49.5) | 71 (49.6) | 74 (49.3) | 0.88 |
Surgical approach, % | 0.81 | |||
Open | 97 (33.2) | 49 (34.4) | 48 (33) | |
Laparoscopic | 192 (65.6) | 92 (64) | 100 (66) | |
Robotic | 4 (1.2) | 2 (1.6) | 2 (1) | |
Diverting ileostomy, % | 165 (56.3) | 85 (59.4) | 80 (53.3) | 0.43 |
Time of surgery (±SD) | 270 ± 56 | 273 ± 87 | 265 ± 94 | 0.54 |
Anastomotic leakage, % | 35 (14.6) | 11 (7.7) | 24 (16) | 0.001 |
Change in intraoperative plan after ICGFA, % | 7 (4.9) | 7 (4.9) | 0 (0) | - |
Change in intraoperative plan after doughnuts inspection, % | 0 (0) | 0 (0) | 0 (0) | - |
Change in intraoperative plan after Air leak test, % | 3 (2.1) | 3 (2.1) | 0 (0) | - |
Change in intraoperative plan after endoscopic evaluation, % | 1 (0.7) | 1 (0.7) | 0 (0) | - |
Change in intraoperative plan after quadruple control, % | 11 (7.7) | 11 (7.7) | 0 (0) | - |
Length of stay, days (±SD) | 9.3 ± 6.4 | 8.2 ± 5.7 | 10.2 ± 7.1 | 0.09 |
30-day mortality, % | 9 (3) | 5 (3.5) | 4 (2.6) | 0.65 |
Quadruple Control Group n = 130 | Control Group n = 130 | p | |
---|---|---|---|
Mean age (± SD) | 70.79 ± 10.95 | 68.12 ± 10.52 | 0.184 |
Gender, % | 0.078 | ||
Male | 71 (54.79) | 85 (65.75) | |
Female | 59 (45.21) | 45 (34.25) | |
ASA score, % | 0.49 | ||
1/2 | 75 (57.7) | 72 (55.4) | |
3/4 | 55 (42.3) | 58 (44.6) | |
Comorbidity, % | 85 (65.4) | 88 (67.7) | 0.58 |
Tumour distance from AV, % | 0.56 | ||
>10 cm | 44 (34.25) | 41 (31.51) | |
5.1–10 cm | 50 (38.36) | 57 (43.84) | |
<5 cm | 36 (27.4) | 32 (24.7) | |
nCRT, % | 60 (46.1) | 63 (48.5) | 0.88 |
Diverting ileostomy, % | 62 (47.7) | 65 (50) | 0.43 |
Time of surgery (±SD) | 253 ± 57 | 265 ± 64 | 0.44 |
Anastomotic leakage, % | 7 (5.4) | 16 (12.3) | 0.001 |
| 0 | 2 | |
| 2 | 5 | |
| 5 | 9 | |
| 7 | 14 | |
Bleeding, % | 1 (0.08) | 2 (1.5) | 0.56 |
Ileus, % | 4 (3.1) | 3 (2.3) | 0.6 |
Surgical site infection, % | 5 (3.8) | 3 (2.3) | 0.23 |
Pneumonia, % | 3 (2.3) | 4 (3.1) | 0.6 |
Urinary tract infection, % | 2 (1.5) | 3 (2.3) | 0.32 |
Lenght of stay, days (±SD) | 8.2 ± 5.7 | 10.2 ± 7.1 | 0.09 |
30-day mortality | 2 (1.5) | 2 (1.5) | 0.65 |
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Carannante, F.; Piozzi, G.N.; Miacci, V.; Bianco, G.; Melone, G.; Schiavone, V.; Costa, G.; Caricato, M.; Khan, J.S.; Capolupo, G.T. Quadruple Assessment of Colorectal Anastomosis after Laparoscopic Rectal Resection: A Retrospective Analysis of a Propensity-Matched Cohort. J. Clin. Med. 2024, 13, 5092. https://doi.org/10.3390/jcm13175092
Carannante F, Piozzi GN, Miacci V, Bianco G, Melone G, Schiavone V, Costa G, Caricato M, Khan JS, Capolupo GT. Quadruple Assessment of Colorectal Anastomosis after Laparoscopic Rectal Resection: A Retrospective Analysis of a Propensity-Matched Cohort. Journal of Clinical Medicine. 2024; 13(17):5092. https://doi.org/10.3390/jcm13175092
Chicago/Turabian StyleCarannante, Filippo, Guglielmo Niccolò Piozzi, Valentina Miacci, Gianfranco Bianco, Gennaro Melone, Vincenzo Schiavone, Gianluca Costa, Marco Caricato, Jim S. Khan, and Gabriella Teresa Capolupo. 2024. "Quadruple Assessment of Colorectal Anastomosis after Laparoscopic Rectal Resection: A Retrospective Analysis of a Propensity-Matched Cohort" Journal of Clinical Medicine 13, no. 17: 5092. https://doi.org/10.3390/jcm13175092