Brucella Spondylitis: Current Knowledge and Recent Advances

Spernovasilis, Nikolaos; Karantanas, Apostolos; Markaki, Ioulia; Konsoula, Afroditi; Ntontis, Zisis; Koutserimpas, Christos; Alpantaki, Kalliopi

doi:10.3390/jcm13020595

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Brucella Spondylitis: Current Knowledge and Recent Advances

by

Nikolaos Spernovasilis

^1,*

,

Apostolos Karantanas

^2,3,4,

Ioulia Markaki

⁵,

Afroditi Konsoula

⁶,

Zisis Ntontis

⁷,

Christos Koutserimpas

⁸ and

Kalliopi Alpantaki

^7,*

¹

Department of Infectious Diseases, German Oncology Center, 4108 Limassol, Cyprus

²

Department of Medical Imaging, University Hospital of Heraklion, 71500 Heraklion, Greece

³

Advanced Hybrid Imaging Systems, Institute of Computer Science, FORTH, 71500 Heraklion, Greece

⁴

Department of Radiology, School of Medicine, University of Crete, 71003 Heraklion, Greece

⁵

Internal Medicine Department, Thoracic Diseases General Hospital Sotiria, 11527 Athens, Greece

⁶

Department of Pediatrics, General Hospital of Sitia, 72300 Sitia, Greece

⁷

Department of Orthopaedics and Trauma Surgery, Venizeleio General Hospital of Heraklion, 71409 Heraklion, Greece

⁸

Department of Orthopaedics and Traumatology, “251” Hellenic Air Force General Hospital of Athens, 11525 Athens, Greece

^*

Authors to whom correspondence should be addressed.

J. Clin. Med. 2024, 13(2), 595; https://doi.org/10.3390/jcm13020595

Submission received: 10 November 2023 / Revised: 15 January 2024 / Accepted: 16 January 2024 / Published: 19 January 2024

(This article belongs to the Special Issue Spinal Infections: Pathogenesis, Diagnosis, Management and Outcomes)

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Abstract

The most prevalent zoonotic disease is brucellosis, which poses a significant threat for worldwide public health. Particularly in endemic areas, spinal involvement is a major source of morbidity and mortality and can complicate the course of the disease. The diagnosis of Brucella spondylitis is challenging and should be suspected in the appropriate epidemiological and clinical context, in correlation with microbiological and radiological findings. Treatment depends largely on the affected parts of the body. Available treatment options include antibiotic administration for an adequate period of time and, when appropriate, surgical intervention. In this article, we examined the most recent data on the pathophysiology, clinical manifestation, diagnosis, and management of spinal brucellosis in adults.

Keywords: Brucella; brucellosis; spine; spondylitis; spondylodiscitis; imaging

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MDPI and ACS Style

Spernovasilis, N.; Karantanas, A.; Markaki, I.; Konsoula, A.; Ntontis, Z.; Koutserimpas, C.; Alpantaki, K. Brucella Spondylitis: Current Knowledge and Recent Advances. J. Clin. Med. 2024, 13, 595. https://doi.org/10.3390/jcm13020595

AMA Style

Spernovasilis N, Karantanas A, Markaki I, Konsoula A, Ntontis Z, Koutserimpas C, Alpantaki K. Brucella Spondylitis: Current Knowledge and Recent Advances. Journal of Clinical Medicine. 2024; 13(2):595. https://doi.org/10.3390/jcm13020595

Chicago/Turabian Style

Spernovasilis, Nikolaos, Apostolos Karantanas, Ioulia Markaki, Afroditi Konsoula, Zisis Ntontis, Christos Koutserimpas, and Kalliopi Alpantaki. 2024. "Brucella Spondylitis: Current Knowledge and Recent Advances" Journal of Clinical Medicine 13, no. 2: 595. https://doi.org/10.3390/jcm13020595

APA Style

Spernovasilis, N., Karantanas, A., Markaki, I., Konsoula, A., Ntontis, Z., Koutserimpas, C., & Alpantaki, K. (2024). Brucella Spondylitis: Current Knowledge and Recent Advances. Journal of Clinical Medicine, 13(2), 595. https://doi.org/10.3390/jcm13020595

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Brucella Spondylitis: Current Knowledge and Recent Advances

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