Characteristic Differences between Normotensive and Hypertensive Pseudoexfoliative Glaucoma
Abstract
:1. Introduction
2. Methods
2.1. Patients
2.2. PXG
2.3. Hypertensive and Normotensive PXG
2.4. Posterior Pole Profile
2.5. Laminar Cribrosa Assessment by SS-OCT
2.6. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Hypertensive PXG (86 Eyes) | Normotensive PXG (80 Eyes) | p-Value |
---|---|---|---|
Age, year | 73.78 ± 8.41 | 73.58 ± 10.08 | 0.890 |
Sex, M/F | 53/33 | 28/53 | <0.001 |
CCT, μm | 544.71 ± 61.84 | 523.30 ± 32.15 | 0.021 |
Axial length, mm | 23.70 ± 1.04 | 23.85 ± 1.24 | 0.451 |
Hypertension, n (%) | 35 (40.7%) | 28 (34.6%) | 0.414 |
Diabetes, n (%) | 14(13.3%) | 8 (9.9%) | 0.200 |
Pseudophakia, n | 37 (44.0%) | 23 (28.4%) | 0.037 |
Medication eyedrop | 1.63 ± 0.75 | 1.93 ± 1.02 | 0.032 |
Glaucoma surgery history | 52 (60.5%) | 4 (4.9%) | <0.001 |
Mean IOP, mmHg | 17.95 ± 6.60 | 14.30 ± 2.95 | <0.001 |
Corrected mean IOP, mmHg | 18.22 ± 6.95 | 15.17 ± 3.37 | 0.001 |
Peak IOP, mmHg | 30.68 ± 8.25 | 17.78 ± 2.82 | <0.001 |
Corrected peak IOP, mmHg | 30.84 ± 8.33 | 18.53 ± 3.27 | <0.001 |
RNFL thickness, μm | 59.08 ± 11.75 | 66.74 ± 9.84 | <0.001 |
VF MD, dB | −17.59 ± 10.91 | −8.69 ± 8.32 | <0.001 |
Follow-up period, year | 5.69 ± 3.81 | 5.26 ± 3.13 | 0.470 |
Tilt ratio | 1.12 ± 0.94 | 1.14 ± 0.12 | 0.361 |
Torsion ratio | 90.73 ± 6.96 | 89.44 ± 8.63 | 0.611 |
Disc fovea angle | −6.68 ± 5.36 | −6.20 ± 4.06 | 0.563 |
PPA/Disc area > 0.4 | 18 (20.5%) | 20 (25.0%) | 0.533 |
Variable | Hypertensive PXG (32 Eyes) | Normotensive PXG (32 Eyes) | p Value |
---|---|---|---|
Age, year | 74.78 ± 8.91 | 75.22 ± 7.99 | 0.837 |
Axial length, mm | 23.47± 0.81 | 23.68 ± 1.02 | 0.434 |
RNFL thickness, μm | 68.13 ± 11.45 | 69.00 ± 10.76 | 0.754 |
VF MD, dB | −9.02 ± 8.78 | −8.92 ± 8.71 | 0.962 |
VF PSD, dB | 5.68 ± 4.14 | 6.01 ± 3.48 | 0.737 |
Lamina Cribrosa Thickness | |||
Mid-superior, μm | 176.16 ± 22.74 | 151.66 ± 20.88 | <0.001 |
Center, μm | 188.50 ± 29.21 | 176.63 ± 24.70 | 0.084 |
Mid-inferior, μm | 171.19 ± 31.70 | 151.25 ± 22.31 | 0.005 |
Mean, μm | 178.61 ± 15.74 | 159.84 ± 15.60 | <0.001 |
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Shin, D.Y.; Park, C.K.; Lee, N.Y. Characteristic Differences between Normotensive and Hypertensive Pseudoexfoliative Glaucoma. J. Clin. Med. 2024, 13, 1078. https://doi.org/10.3390/jcm13041078
Shin DY, Park CK, Lee NY. Characteristic Differences between Normotensive and Hypertensive Pseudoexfoliative Glaucoma. Journal of Clinical Medicine. 2024; 13(4):1078. https://doi.org/10.3390/jcm13041078
Chicago/Turabian StyleShin, Da Young, Chan Kee Park, and Na Young Lee. 2024. "Characteristic Differences between Normotensive and Hypertensive Pseudoexfoliative Glaucoma" Journal of Clinical Medicine 13, no. 4: 1078. https://doi.org/10.3390/jcm13041078