Soft Palate and Pharyngeal Surgery for the Treatment of Snoring: A Systematic Review
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Search Strategy
- Non-English articles (n = 100)
- Studies involving pediatric populations (n = 435)
- Systematic reviews or meta-analyses (n = 200)
- Articles not including the word “snoring” in the title
- Duplicate records
2.2. Inclusion and Exclusion Criteria
- Pediatric populations
- Isolated nasal procedures without snoring-specific outcomes
- Non-surgical or purely pharmacological interventions
- Lack of VAS score
- Case reports
2.3. Study Categorization and Surgical Techniques
- Type of anesthesia: Patients were grouped according to whether the procedure was performed under general or local anesthesia, as documented in the operative reports.
- Tonsillectomy: The cohort was divided into two subgroups based on whether or not tonsillectomy was performed in conjunction with the primary surgical procedure.
- Surgical technique: The surgical approach was classified into two main types as follows:
- Anterior techniques, which primarily addressed the soft palate and/or uvula, including procedures such as anterior palatoplasties, infiltrative radiofrequency of the soft palate, and palatal implants.
- Lateral/circumferential techniques, which targeted the lateral pharyngeal wall and/or involved circumferential modifications of the pharyngeal airway. This group included techniques such as lateral pharyngoplasty, expansion sphincter pharyngoplasty, and modified versions of barbed reposition pharyngoplasty with lateral traction (modified BRP).
- 4.
- Body Mass Index (BMI): patients were stratified into two groups according to their BMI:
- ○
- BMI ≤ 27
- ○
- BMI > 27
- 5.
- Apnea-Hypopnea Index (AHI): patients were categorized based on the severity of preoperative obstructive sleep apnea, using the following thresholds:
- ○
- AHI ≤ 30 events/hour
- ○
- AHI > 30 events/hour
2.4. Preoperative Evaluation and DISE Use
2.5. Outcome Measure: Visual Analog Scale (VAS)
2.6. Data Extraction and Statistical Analysis
2.7. Risk of Bias Assessment
3. Results
3.1. Overall Outcomes
3.1.1. Surgical Technique Comparison
- In the ANT group, the mean preoperative VAS was 8.11 and decreased to 3.99 postoperatively, resulting in a ΔVAS of 4.12 (Table 3).
- In the LAT/CIRC group, the mean preoperative VAS was lower, at 6.35, with a postoperative VAS of 2.67 and a ΔVAS of 3.68 (Table 3).
3.1.2. Anesthesia Type
- General anesthesia (417 patients): VAS decreased from 6.82 to 2.86 (ΔVAS 3.96).
- Local anesthesia (282 patients): VAS decreased from 8.04 to 4.18 (ΔVAS 3.86).
3.1.3. Tonsillectomy
- The tonsillectomy group showed a higher preoperative VAS (7.9), but also a significantly lower postoperative VAS (2.73), resulting in a ΔVAS of 5.17.
- The non-tonsillectomy group had a preoperative VAS of 7.17 and a postoperative VAS of 2.68, with a ΔVAS of 4.49.
3.1.4. OSAS Severity (AHI)
- AHI ≤ 30 (360 patients): VAS decreased from 8.26 to 4.24 (ΔVAS 4.03).
- AHI > 30 (356 patients): VAS decreased from 6.31 to 2.76 (ΔVAS 3.55).
3.1.5. BMI Subgroups
- BMI ≤ 27 (253 patients, six studies): VAS decreased from 8.1 to 3.9 (ΔVAS 4.2).
- BMI > 27 (411 patients, 11 studies): VAS decreased from 6.72 to 3.0 (ΔVAS 3.7).
3.1.6. Risk of Bias Analysis
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
OSA | obstructive sleep apnea |
BRP | barbed repositioning pharyngoplasty |
AHI | Apnea Hypopnea Index |
BMI | Body mass index |
DISE | drug induced sleep endoscopy |
VAS | visual analog scale |
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Title | Author (Year) | Study Design | Level of Evidence | Number of Patients | Mean Age | Snoring/OSA | DISE | Mean Follow-Up | |
---|---|---|---|---|---|---|---|---|---|
1 | A new office-based procedure for treatment of snoring: The S.I.Le.N.C.E. study | Friedman M et al. (2020) [4] | Prospective | Level 4 | 52 | n.s. | Snoring | No | 6 months |
2 | Barbed snore surgery for concentric collapse at the velum: The Alianza technique | Mantovani M et al. (2017) [5] | Pilot Longitudinal Study | Level 4 | 19 | 43.8 | Mild-moderate OSA | Yes | 6 months |
3 | The effectiveness of combined tonsillectomy and anterior palatoplasty in the treatment of snoring and obstructive sleep apnea (OSA) | Adzrel B et al. (2016) [6] | Prospective | Level 4 | 31 | 35 | Snoring +/− OSA | No | 74 months |
4 | An absorbable thread suture technique to treat snoring | Kwon JW et al. (2015) [7] | Observational | Level 4 | 35 | 34.2 | Snoring, mild OSA | No | 90 days |
5 | Changes of snoring sound after relocation pharyngoplasty for obstructive sleep apnea: the surgery reduces mean intensity in snoring which correlates well with apoea-hypopnea index | Li HY et al. (2015) [8] | Prospective Case Series | Level 4 | 32 | 39 | OSA | No | 6 months |
6 | Optimal application of soft-palate webbing flap pharyngoplasty combined with nasal surgery for surgical treatment of primary snoring and obstructive sleep apnea. | Park JA et al. (2022) [9] | Retrospective | Level 3 | 174 | 45.1 | OSA | Yes | 6 months |
7 | The Efficacy of Diode Laser Palatoplasty on Patients with Troublesome Snoring | Dawood MR et al. (2020) [10] | Prospective Interventional | Level 4 | 46 | 45.31 | Snoring | No | 6 months |
8 | Radiofrequency ablation of the lateral palatal space for snoring | Tucker Woodson B et al. (2018) [11] | Retrospective Chart Review | Level 3 | 20 | n.s. | Snoring | No | n.s. |
9 | A tertiary center experience with velopharyngeal surgical techniques for treatment of snoring and obstructive sleep apnea | Karacoc O et al. (2018) [12] | Prospective Series | Level 4 | 93 | 40.7 | Snoring or OSA | No | 5.90 months |
10 | The treatment of snoring by radiofrequency-assisted uvulopalatoplasty and results after one-session protocol: a prospective, longitudinal, non-randomized study | Chiesa Estomba CM et al. (2015) [13] | Prospective Longitudinal Non Randomized | Level 4 | 27 | 49 | Snoring | No | 12 months |
11 | Soft palatal webbing flap palatopharyngoplasty for both soft palatal and oropharyngeal lateral wall collapse in the treatment of snoring and obstructive sleep apnea: a new innovative technique without tonsillectomy | Elbassiouny AMME (2015) [14] | Single-Center Prospective Uncontrolled Case Series | Level 4 | 28 | 41.3 | Snoring or OSA | Yes | 6 months |
12 | No-cutting remodeling intra-pharyngeal surgery can avoid CPAP in selected OSA patients: Myth or reality? | Casale M. et al. (2022) [15] | Prospective Clinical Trial | Level 4 | 26 | 52.7 | OSA | Yes | 6.5 months |
13 | Technical update of barbed pharyngoplasty for retropalatal obstruction in obstructive sleep apnea | Babademez MA et al. (2019) [16] | Prospective | Level 2 | 34 | BRP = 39.4 MBRP = 40.1 | Mild-moderate OSA | Yes | 8 months |
14 | Modified barbed soft palatal posterior pillar webbing flap palatopharyngoplasty | Elbassiouny AMME (2016) [17] | Prospective Single Center Uncontrolled Case Series | Level 4 | 21 | 31.3 | OSA | Yes | 6 months |
15 | Barbed anterior pharyngoplasty: An evolution of anterior palatoplasty | Salamanca F et al. (2014) [18] | Not Specified | Level 4 | 24 | 46 | Snoring or mild OSA | Yes | 6 weeks |
16 | Treatment of snoring using a non-invasive Er:YAG laser with SMOOTH mode (NightLase): a randomized controlled trial. | Picavet VA et al. (2023) [19] | Prospective 20 vs. 20 | Level 2 | 40 | 43.3 vs. 44.5 | Snoring or mold OSA | No | 3 months |
17 | Radiofrequency of the soft palate for sleep-disordered breathing: a 6-year follow-up study | De Kermadec H et al. (2014) [20] | Observational Retrospective | Level 4 | 77 | 52.2 | Mild-moderate OSA | No | 6.3 years |
18 | Outpatient erbium:YAG (2940 nm) laser treatment for snoring: a prospective study on 40 patients. | Storchi IF et al. (2018) [21] | Prospective | Level 4 | 40 | 53.1 | Snoring and mild, moderate, severe OSA | No | 20 months |
19 | The palatal septal cartilage implantation for snoring and obstructive sleep apnea | Lee YC et al. (2018) [22] | Retrospective | Level 4 | 10 | 45 | Snoring and OSA | No | 12 months |
Authors | References | Year | N | Technique | Type | VAS Pre (Mean ± DS) | VAS Post (Mean ± DS) | VAS (Mean) |
---|---|---|---|---|---|---|---|---|
Li et al. | [8] | 2015 | 32 | Relocation Pharingoplasty | Lat/circ | 7.5 ± 1.9 | 2.6 ± 1.8 | 4.9 |
Casale et al. | [15] | 2022 | 26 | Alianza | Lat/circ | 7.85 ± 1.23 | 3.2 ± 1.7 | 4.65 |
Babademez et al. | [16] | 2019 | 17 | Modified barbed pharyngoplasty | Lat/circ | 8 ± 1.5 | 1.8 ± 0.8 | 6.2 |
Babademez et al. | [16] | 2019 | 17 | Barbed pharyngoplasty | Lat/circ | 6.2 ± 1.9 | 2.2 ± 1 | 4 |
Elbassiouny et al. | [17] | 2016 | 21 | Modified barbed pharyngoplasty | Lat/circ | 9.4 ± 1.6 | 1.7 ± 3.2 | 7.7 |
Bakri Adzreil et al. | [6] | 2016 | 31 | Anterior pharyngoplasty and tonsillectomy | Ant | 7.3 ± 1.0 | 2.9 ± 1.6 | 4.4 |
Lee et al. | [22] | 2018 | 10 | Septum Cartilage Implantation | Ant | 8 ±0.74 | 4.5 ± 2.59 | 3.5 |
Friedman et al. | [4] | 2020 | 52 | Elevoplasty | Ant | 7.81 ± 1.9 | 5.4 ± 2.2 | 2.41 |
Mantovani et al. | [5] | 2017 | 19 | Alianza | Lat/circ | 9.5 ± 0.7 | 2.1 ±1.7 | 7.4 |
Jangwoo Kwon et al. | [7] | 2015 | 35 | Stiffness of the soft palate | Ant | 8.74 ± 2.28 | 4.14 ± 1.68 | 4.6 |
Park et al. | [9] | 2022 | 174 | Soft palatal webbing flap pharyngoplasty and nasal surgery | Lat/circ | 4.7 | 2.9 | 1.8 |
Dawood et al. | [10] | 2020 | 46 | Diode Laser Palatoplasty | Ant | 6.6 | 2.4 | 4.2 |
Estomba et al. | [13] | 2015 | 27 | RFA Uvulopalatoplasty | Ant | 8.10 ± 0.93 | 4.90 ± 0.77 | 3.2 |
Elbassiouny et al. | [14] | 2015 | 28 | Soft palatal webbing flap pharyngoplasty | Lat/circ | 8.6 ± 3.7 | 2.3 ± 2.7 | 6.3 |
Salamanca et al. | [18] | 2014 | 24 | Barbed anterior pharyngoplasty | Ant | 9.2 | 2.9 | 6.3 |
Picavet et al. | [19] | 2023 | 40 | Laser palatoplasty | Ant | 7.9 ± 2.0 | 4.7 ± 2.8 | 3.2 |
De Kermadec et al. | [20] | 2014 | 77 | RFA Uvulopalatoplasty | Ant | 8.1 ± 1.5 | 5.7 ± 2.9 | 2.4 |
Storchi et al. | [21] | 2018 | 40 | Laser pharyngoplasty | Ant | 10 ± 1.48 | 3 ± 2.96 | 7 |
Patients | VAS Pre | VAS Post | ΔVAS | ||
---|---|---|---|---|---|
Anesthesia | |||||
general | 417 | 6.82 | 2.86 | 3.96 | |
local | 282 | 8.04 | 4.18 | 3.86 | |
Tonsillectomy | |||||
yes | 137 | 7.9 | 2.73 | 5.17 | |
no | 562 | 7.17 | 2.68 | 4.49 | |
Surgical technique | |||||
Anterior pharyngoplasty | 382 | 8.11 | 3.99 | 4.12 | |
Lateral/Circular pharyngoplasty | 317 | 6.35 | 2.67 | 3.68 | |
AHI | |||||
AHI > 30 | 356 | 8.26 | 4.23 | 4.03 | |
AHI < 30 | 360 | 6.31 | 2.76 | 3.55 | |
BMI | |||||
BMI < 27 | 253 | 8.1 | 3.9 | 4.2 | |
BMI > 27 | 411 | 6.72 | 3 | 3.7 |
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Cammaroto, G.; Caccamo, G.; Rodella, T.; Angeletti, D.; Boscolo Nata, F.; Topazio, D.; Cerritelli, L. Soft Palate and Pharyngeal Surgery for the Treatment of Snoring: A Systematic Review. J. Clin. Med. 2025, 14, 4964. https://doi.org/10.3390/jcm14144964
Cammaroto G, Caccamo G, Rodella T, Angeletti D, Boscolo Nata F, Topazio D, Cerritelli L. Soft Palate and Pharyngeal Surgery for the Treatment of Snoring: A Systematic Review. Journal of Clinical Medicine. 2025; 14(14):4964. https://doi.org/10.3390/jcm14144964
Chicago/Turabian StyleCammaroto, Giovanni, Giuseppe Caccamo, Tommaso Rodella, Diletta Angeletti, Francesca Boscolo Nata, Davide Topazio, and Luca Cerritelli. 2025. "Soft Palate and Pharyngeal Surgery for the Treatment of Snoring: A Systematic Review" Journal of Clinical Medicine 14, no. 14: 4964. https://doi.org/10.3390/jcm14144964
APA StyleCammaroto, G., Caccamo, G., Rodella, T., Angeletti, D., Boscolo Nata, F., Topazio, D., & Cerritelli, L. (2025). Soft Palate and Pharyngeal Surgery for the Treatment of Snoring: A Systematic Review. Journal of Clinical Medicine, 14(14), 4964. https://doi.org/10.3390/jcm14144964