Association between Bladder Outlet Obstruction and Bladder Cancer in Patients with Aging Male
, Chen-Pang Hou 1,2,3,†, Horng-Heng Juang 1,2,4, Phei-Lang Chang 1,2, Tien-Hsing Chen 2,5, Chien-Lun Chen 1,2 and Ke-Hung Tsui 1,2,*Round 1
Reviewer 1 Report
The authors present this work about the association between bladder cancer and bladder obstruction. The manuscript is very well organize and clear, and the information presented in this work is of relevance for the scientific community. My only minor drawback is that a minor english review could improve the manuscript comprehension.
Author Response
Dear Editor :
Thanks to the editor for giving us the opportunity to make the article more intimate, the following changes are made according to the editors suggestions.
Reviewer 1
The authors present this work about the association between bladder cancer and bladder obstruction. The manuscript is very well organize and clear, and the information presented in this work is of relevance for the scientific community. My only minor drawback is that a minor english review could improve the manuscript comprehension.
Ans: We have followed the comment to English modified proof. Please see attach file 1.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
In the present study, the authors investigated the associations between the treatment outcomes of benign prostatic hyperplasia (BPH) and lifelong health status in patients who received transurethral resection of the prostate (TURP) and patients who were prescribed alpha-blockers. You concluded unfavorable treatment outcomes of BPH are associated with a higher incidence of bladder cancer, and unfavorable outcomes of medication treatment are associated with a higher risk of all-cause mortality. The study is interesting, but there is an illogical leap in what you said. There are some major points to propound:
You should discuss why unfavorable treatment outcomes of BPH are associated with a higher incidence of bladder cancer, additionally why unfavorable outcomes of medication treatment are associated with a higher risk of all-cause mortality.
Author Response
Dear Editor :
Thanks to the editor for giving us the opportunity to make the article more intimate, the following changes are made according to the editors suggestions.
Reviewer 1
The authors present this work about the association between bladder cancer and bladder obstruction. The manuscript is very well organize and clear, and the information presented in this work is of relevance for the scientific community. My only minor drawback is that a minor english review could improve the manuscript comprehension.
Ans: We have followed the comment to English modified proof. Please see attach file 1.
Author Response File: Author Response.pdf
