Impact of Antiplatelet Therapies on Patients Outcome in Osteosynthetic Surgery of Proximal Femoral Fractures
Abstract
:1. Introduction
2. Methods
Hemoglobin balance: Hbtotalloss = Blood volume (mL) × (Hb before surgery − Hb after surgery) × 0.001 + the total amount of hemoglobin of transfusions (52g Hb per blood transfusion)[14]
Statistics
3. Results
4. Discussion
Limitations of the Study
5. Conclusions
Author Contributions
Acknowledgments
Conflicts of Interest
References
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Total | % | Male | % | Female | % | Mean age | ASA | |
---|---|---|---|---|---|---|---|---|
Total | 396 | 100 | 93 | 23.5 | 303 | 76.5 | 80.4 | 1.9 |
APT | 221 | 55.8 | 42 | 45.2 | 179 | 59.1 | 83.7 | 1.8 |
ASS | 189 | 47.7 | 34 | 36.6 | 155 | 51.2 | 83.6 | 1.6 |
Clopidogrel | 20 | 5.1 | 3 | 3.2 | 17 | 5.6 | 85 | 2.6 |
Dual APT | 12 | 3 | 5 | 5.4 | 7 | 2.3 | 82.1 | 2.7 |
No APT | 174 | 43.9 | 51 | 54.8 | 124 | 40.9 | 76.4 | 2.1 |
Fracture type | total (%) | APT (%) | no APT (%) | p |
---|---|---|---|---|
All fractures | 396 (100) | 221 (56) | 175 (44) | 0.024 |
Femoral neck fracture | 81 (20) | 41 (51) | 40 (49) | 1.000 |
Trochanteric fracture | 295 (75) | 169 (57) | 126 (43) | 0.014 |
Subtrochanteric fracture | 20 (5) | 11 (55) | 9 (45) | 0.824 |
Type of surgery | ||||
Screws | 29 (7.3) | 17 (59) | 12 (41) | 0.458 |
DHS | 53 (13.4) | 24 (45) | 29 (55) | 0.583 |
Intramedullary nail | 314 (79.3) | 180 (57) | 134 (43) | 0.011 |
Comorbidities | ||||
Arterial hypertension | 138 (35) | 76 (55) | 62 (45) | 0.829 |
Coronary heart disease | 46 (12) | 40 (87) | 6 (13) | 0.000 |
Myocardial insufficiency | 13 (3) | 6 (46) | 7 (54) | 0.476 |
Peripheral artery disease | 19 (5) | 17 (89) | 2 (11) | 0.002 |
Cerebral artery disease or stroke | 24 (6) | 5 (20) | 20 (80) | 0.017 |
Atrial fibrillation | 26 (7) | 14 (54) | 12 (46) | 0.835 |
Diabetes | 45 (11) | 28 (62) | 17 (38) | 0.357 |
History of carcinoma | 20 (5) | 8 (40) | 12 (60) | 0.144 |
Renal insufficiency | 20 (5) | 9 (45) | 11 (55) | 0.318 |
History of DVT or PE | 6 (2) | 0 (0) | 6 (100) | 0.006 |
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Humenberger, M.; Stockinger, M.; Kettner, S.; Siller-Matula, J.; Hajdu, S. Impact of Antiplatelet Therapies on Patients Outcome in Osteosynthetic Surgery of Proximal Femoral Fractures. J. Clin. Med. 2019, 8, 2176. https://doi.org/10.3390/jcm8122176
Humenberger M, Stockinger M, Kettner S, Siller-Matula J, Hajdu S. Impact of Antiplatelet Therapies on Patients Outcome in Osteosynthetic Surgery of Proximal Femoral Fractures. Journal of Clinical Medicine. 2019; 8(12):2176. https://doi.org/10.3390/jcm8122176
Chicago/Turabian StyleHumenberger, Michael, Matthias Stockinger, Stephan Kettner, Jolanta Siller-Matula, and Stefan Hajdu. 2019. "Impact of Antiplatelet Therapies on Patients Outcome in Osteosynthetic Surgery of Proximal Femoral Fractures" Journal of Clinical Medicine 8, no. 12: 2176. https://doi.org/10.3390/jcm8122176