Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial
Abstract
:1. Introduction
2. Experimental Section
2.1. Patients
2.2. Anesthesia
2.3. SRS
2.4. Abdominal Wall Length
2.5. Statistics
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Variables: | Age (years) | Height (cm) | Weight (kg) | BMI (kg/cm2) | Rocuronium (mg) Initial Dose | Rocuronium (mg) Repetition |
---|---|---|---|---|---|---|
Mean (SD) | 50.9 (13.4) | 167.4 (5.4) | 70.8 (13.9) | 25.2 (4.5) | 37.4 (3.8) | 17.9 (7.2) |
Drugs | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% |
---|---|---|---|---|---|
Propofol infusion: mg kg h−1 (mean (SD)) | 3.7 (0.7) | 3.8 (0.8) | 3.6 (0.8) | 3.8 (1.0) | 3.8 (0.9) |
Remifentanil infusion: µg kg min−1 (mean (SD)) | 0.12 (0.03) | 0.13 (0.03) | 0.13 (0.03) | 0.14 (0.03) | 0.14 (0.04) |
Sufentanil bolus: number | 12 | 14 | 3 | 12 | 3 |
Sufentanil bolus: mg (mean (SD)) | 15.0 (7.1) | 11.1 (5.6) | 13.3 (5.8) | 10.0 (4.3) | 8.3 (2.9) |
Rocuronium bolus: number | 0 | 0 | 5 | 1 | 0 |
Rocuronium bolus: mg (mean (SD)) | - | - | 13 (4.5) | 10 | - |
Variables: | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
BIS | 41.6 (5.5) | 41.9 (6.3) | 41.3 (5.0) | 42.8 (5.5) | 43.5 (4.6) | n.s. |
BP syst (mm Hg) | 96.8 (18.2) | 105.6 (21.1) | 110.1 (18.0) * | 109.4 (16.6) * | 102.4 (15.7) | *: p < 0.001 vs. PTC = 0 |
BP diast (mm Hg) | 56.6 (11.7) | 63.4 (13.7) * | 67.8 (10.1) * + | 65.6 (10.2) * + | 60.0 (7.7) | *: p < 0.001 vs. PTC = 0 +: p <0.008 vs. TOFR > 90% |
HR | 56.1 (8.9) | 56.9 (8.1) | 58.3 (9.6) # | 57.4 (8.8) | 55.9 (8.8) | #: p < 0.05 vs. TOFR > 90% |
Abdominal Wall Length | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
Increase in mm: mean (SD) | 11.5 (4.6) | 11.5 (4.9) | 10.5 (4.5) | 11.1 (5.9) | 10.6 (5.2) | 0.17 |
SRS | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
SRS (mean (SD)) | 4.7 (0.5) | 4.6 (0.5) | 4.6 (0.5) | 4.6 (0.6) | 4.5 (0.5) * | *: p = 0.025 vs. PTC = 0 |
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Soltesz, S.; Mathes, A.; Anapolski, M.; Noé, K.G. Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial. J. Clin. Med. 2020, 9, 1078. https://doi.org/10.3390/jcm9041078
Soltesz S, Mathes A, Anapolski M, Noé KG. Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial. Journal of Clinical Medicine. 2020; 9(4):1078. https://doi.org/10.3390/jcm9041078
Chicago/Turabian StyleSoltesz, Stefan, Alexander Mathes, Michael Anapolski, and Karl Guenter Noé. 2020. "Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial" Journal of Clinical Medicine 9, no. 4: 1078. https://doi.org/10.3390/jcm9041078