Feasibility of Gynaecologist Led Lynch Syndrome Testing in Women with Endometrial Cancer
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Familial and Psychological Assessments
2.3. Statistical Analysis
3. Results
3.1. Study Participants
3.2. Time Taken to Consent for Lynch Syndrome Testing
3.3. Baseline Characteristics of the Cohorts
3.4. Motivations for Testing
3.5. Anxiety about Testing
3.6. Lynch Syndrome Testing Outcomes
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Questionnaire Subsection | Before Surgery (n = 34) | Day of Surgery (n = 50) | In Follow Up (n = 91) | p Value |
---|---|---|---|---|
Prevention Medical Care † | 44 (42, 51), 35–55 | 46 (42, 52), 35–55 | 48 (44, 51), 18.7–55 | 0.19 |
Partners Influence † | 12 (12, 16), 9–16 | 12 (12, 20), 9–20 | 13 (11, 16), 8–20 | 0.42 |
Future Planning | 11.9 (1.9) 8–15 | 12.4 (2.0) 8–15 | 12.5 (2.5) 5–15 | 0.20 |
Ability to Cope | 15.5 (3.2) 8–23 | 16.6 (4.1) 9–24 | 16.3 (4.3) 8–30 | 0.43 |
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Ryan, N.A.J.; Donnelly, L.; Stocking, K.; Evans, D.G.; Crosbie, E.J. Feasibility of Gynaecologist Led Lynch Syndrome Testing in Women with Endometrial Cancer. J. Clin. Med. 2020, 9, 1842. https://doi.org/10.3390/jcm9061842
Ryan NAJ, Donnelly L, Stocking K, Evans DG, Crosbie EJ. Feasibility of Gynaecologist Led Lynch Syndrome Testing in Women with Endometrial Cancer. Journal of Clinical Medicine. 2020; 9(6):1842. https://doi.org/10.3390/jcm9061842
Chicago/Turabian StyleRyan, Neil A. J., Louise Donnelly, Katie Stocking, D. Gareth Evans, and Emma J. Crosbie. 2020. "Feasibility of Gynaecologist Led Lynch Syndrome Testing in Women with Endometrial Cancer" Journal of Clinical Medicine 9, no. 6: 1842. https://doi.org/10.3390/jcm9061842