Preparation and Characterization of Moldable Demineralized Bone Matrix/Calcium Sulfate Composite Bone Graft Materials
Round 1
Reviewer 1 Report
- in conclusion, authors mentioned "We provided the optimal DBM/CSH ratio for this composite moldable putty with good biocompatibility, mechanical strength and the p tentials of osteoinduction/osteoconduction ". But they have tried only one ratio 9:1. could they clarify?
- It is better to report the xrd data of milled DBM
- figure 6b, to understand better show line graph
- how did the authors prepared sample for mechanical tests. please describe in experimental section
Author Response
Please see the attached file.
Author Response File: Author Response.pdf
Reviewer 2 Report
I have reviewed the mansucript Preparation and characterization of moldable demineralized 2 bone matrix/calcium sulfate composite bone graft materials. Overall, the data supports the conclusions made in the mansucript. I have only one comment -
Why reference putty (Osteo-set or Pro-stim) was not compared for the compressive strength and biocompatibility tests? What chemical compositions or interactions are most crucial for the compressive strength?
Author Response
Please see the attached file.
Author Response File: Author Response.pdf
Round 2
Reviewer 1 Report
i recommend to accept the manuscript. the author answered queries and made changes in the manuscript