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Article

Electrochemically Promoted Benzylation of [60]Fullerooxazolidinone

by
Xing-Xing Yan
1,
Chuang Niu
1,
Shi-Qi Ye
1,
Bo-Chen Zhao
1 and
Guan-Wu Wang
1,2,*
1
Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China
2
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
*
Author to whom correspondence should be addressed.
Nanomaterials 2022, 12(13), 2281; https://doi.org/10.3390/nano12132281
Submission received: 1 May 2022 / Revised: 21 June 2022 / Accepted: 28 June 2022 / Published: 1 July 2022
(This article belongs to the Special Issue Fullerene Nanostructures: Synthesis, Functionalities and Applications)
Browse Figures
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Abstract

:
Benzylation of the electrochemically generated dianion from N-p-tolyl-[60]fullerooxazolidinone with benzyl bromide provides three products with different addition patterns. The product distribution can be dramatically altered by varying the reaction conditions. Based on spectral characterizations, these products have been assigned as mono-benzylated 1,4-adduct and bis-benzylated 1,2,3,16- and 1,4,9,25-adducts, respectively. The assigned 1,2,3,16-adduct has been further established by X-ray diffraction analysis. It is believed that the 1,4-adduct is obtained by decarboxylative benzylation of the dianionic species, while bis-benzylated 1,2,3,16- and 1,4,9,25-adducts are achieved via a rearrangement process. In addition, the electrochemical properties of these products have been studied.

Graphical Abstract

1. Introduction

Functionalization of [60]fullerenes (C60) has attracted increasing attention due to their potential applications in biomedical sciences [1,2,3], materials [4,5,6], and perovskite solar cells (PSCs) [7,8,9,10,11]. Scientists have established diverse approaches for the synthesis of various fullerene derivatives [12,13,14,15,16,17,18]. Among them, electrosynthesis has been demonstrated as an efficient and selective method for synthesizing functionalized fullerene derivatives [19,20,21,22,23,24,25].
Recently, the C60-fused heterocyclic derivatives have been frequently used in electrosynthesis, because upon acceptance of electrons, the cleavage of carbon-heteroatom bond in the substrates induces the rearrangement of the fused heterocycle from a [6,6]-bond to a [5,6]-bond and affords novel fullerene derivatives with new addition patterns. Fulleroindolines, as representative fullerene derivatives, have been systematically applied in electrochemical synthesis. Our group demonstrated the electrosynthesis of the 1,2,3,16-adducts from fulleroindoline and alkyl bromides, acyl chlorides, or chloroformates [26,27]. Subsequently, we reported the electrochemical reactions of the fulleroindolines with 1,2-bis(bromomethyl)benzene or phthaloyl chloride, which regioselectively provided 1,2,4,17-adducts [28,29], while the bulky alkyl bromides, such as 2,4,6-tris(bromomethyl)mesitylene and diphenylbromomethane, were also exploited to functionalize fulleroindolines, and afforded 1,2,3,16-adducts and a rare 1,4,9,12-adduct [30]. All of these reactions involved the rearrangement of the indoline moiety from a [6,6]-bond to a [5,6]-bond. Similar electrosynthesis involving rearrangements of heterocyclic moieties on the fullerene surface for other C60-fused heterocycles resulted in 1,2,3,4-, 1,2,3,16- and 1,4,9,25-adducts [31,32,33,34,35]. The electrochemical reactions of heterocyclic fullerene derivatives fused with two heteroatoms have also been reported. The Gao group reported the reaction of dianionic fullerooxazolines with benzyl bromide (BnBr) and successfully obtained a 1,2,3,4-adduct [36]. Later, they obtained two 1,2,3,16-adduct isomers and one 1,2,3,4-adduct isomer by reductive benzylation of fulleroimidazoline [37]. In 2015, Gao and coworkers obtained 1,2,3,16-adducts by electrochemical benzylation of singly bonded 1,2,4,15-C60 dimers with an oxazoline or imidazoline moiety [38]. Among the various fullerene derivatives, fullerooxazolidinone derivatives are of interest because the carbamic moiety is fused to the fullerene skeleton via two heteroatoms. We were thus prompted to investigate the reaction of the dianionic N-p-tolyl-fullerooxazolidinone with BnBr to better understand the electrochemical reactivity of heterocyclic fullerene derivatives fused with two different heteroatoms and to obtain novel fullerene derivatives. To our surprise and satisfaction, a ring-opened decarboxylative mono-benzylated 1,4-adduct and bis-benzylated 1,2,3,16- and 1,4,9,25-adducts by dual benzylations accompanied by the heterocycle rearrangement from a [6,6]-bond to a [5,6]-bond could be obtained from the dianionic N-p-tolyl-fullerooxazolidinone. The phenomenon of ring opening of dianionic C60-fused heterocycles followed by decarboxylation from the resulted dianionic species has no precedent in fullerene chemistry. In this article, we describe the details of these electrochemical benzylations as well as the electrochemical properties of the obtained products.

2. Results and Discussion

Compound 1 was synthesized by the previously reported procedure [39]. As seen from the cyclic voltammogram (CV) of 1, the first redox was reversible, whereas the second redox was electrochemically irreversible (Figure 1). It was found that the CV of 1 was essentially the same at 25 °C and a slightly lower temperature such as 15 °C. This result indicated a cleavage of carbon-heteroatom bond of 1 after accepting two electrons. Previous work on fulleroimidazoline and fullerooxazoline derivatives showed that the C60–O and C60–N could be readily cleaved when they received two electrons [36,37], and we found that 1 (0.02 mmol) could be electrochemically converted at −1.09 V (the trough of the second wave) to dianion 12−, which was readily decomposed to C60 during electrolysis at 25 °C. The electrolysis at lower temperature would slow down the decomposition of dianion 12− to C60, yet required a longer time to reach the theoretical number and would also cause partial decomposition of dianion 12−. On balance, we carried out our experiments on 1 (0.01 mmol) at a lower temperature of 15 °C. By controlled potential electrolysis (CPE) of 1 at −1.09 V in 1,2-C6H4Cl2 solution containing 0.1 M tetra-n-butylammonium perchlorate (TBAP) at 15 °C under an atmosphere of argon, dianion 12− was generated after acceptance of two electrons. Similar to other dianionic C60-fused heterocycles, the ring-opened singly-bonded fullerenyl dianion was attained after addition of two electrons [26,27,28,29,30,31,32,33,34,35,36,37], as confirmed by the very different CV of dianion 12− (Figure S21) compared to that of neutral 1 (Figure 1). Then, 12− was treated with 20 equiv. of NaH and 50 equiv. of BnBr at 15 °C for 1 h (Scheme 1). Surprisingly, a ring-opened mono-benzylated 1,4-adduct 2 was isolated as the major product in 32% yield together with bis-benzylated 1,2,3,16-adduct 3 and 1,4,9,25-adduct 4 in 21% and 4% yields, respectively. The formation of product 2 resulted from decarboxylative benzylation of 12−, which was in sharp contrast with the previously reported benzylation of dianionic C60-fused lactones [40]. The isolation of products 3 and 4 indicated that 12− could react with two molecules of BnBr. For the purpose of enhancing the possibility of adding the second BnBr, the amount of BnBr was increased to 100 equiv., and the yield of the mono-benzylated 1,4-adduct 2 was decreased to 23%, while the competing bis-benzylated 1,2,3,16-adduct 3 was obtained in 29% yield as the major product along with 1,4,9,25-adduct 4 in 3% yield as the minor product. In order to obtain more bis-benzylated 1,2,3,16-adduct 3, the reaction time was further increased to 10 h. Intriguingly, the bis-benzylated 1,2,3,16-adduct 3 could be obtained in 40% yield as the major product along with another bis-benzylated 1,4,9,25-adduct 4 in 14% yield and 1,4-adduct 2 in 4% yield as the minor products. Besides the above products, the reaction mixtures also contained decomposed C60, unreacted 1 and insoluble material (see details in Materials and Methods). It seemed that 1,4-adduct 2 was unstable under our experimental conditions, likely due to the attached arylamino moiety. In brief, when the dianion 12− was treated with 50 equiv. of BnBr for a short reaction time (1 h), mono-benzylated product 2 was the major product along with bis-benzylated products 3 and 4 as minor products. When the amount of BnBr was increased to 100 equiv. for the purpose that the second BnBr could participate in the reaction system, and reaction time was further prolonged (10 h), products 3 and 4 were obtained exclusively accompanied with a small amount of 2. As seen from Scheme 1, the product distribution for the benzylation of 12− could be dramatically manipulated by varying the amount of BnBr and reaction time, either mono-benzylated 1,4-adduct 2 or bis-benzylated 1,2,3,16-adduct 3 could be obtained as the major product.
Products 2–4 were characterized by various spectroscopic data, and 3 was further established by single-crystal X-ray crystallography. The MALDI-TOF mass spectra of 2–4 showed the expected molecular ion peaks. In its 1H NMR spectrum of 2, two doublet peaks at 4.07 and 4.03 ppm with a coupling constant of 13.0 Hz for the methylene protons of the benzyl group attached to the fullerene skeleton and a singlet peak at 2.32 ppm for the methyl group of the p-toluidine moiety were observed. The 1H NMR spectrum of 3 showed an AB quartet at 4.41 and 4.24 ppm with a coupling constant of 13.3 Hz for the methylene protons, while another AB quartet at 2.59 and 2.44 ppm with a coupling constant of 12.9 Hz, indicating that the latter methylene protons were located at the shielding region of a phenyl ring. Likewise, the 1H NMR spectrum of 4 displayed the same phenomena for the chemical shifts and splitting patterns of the methylene protons attached to the fullerene skeleton. Herein, the two benzyl groups should be located at the different sides of the oxazolidinone moiety in compounds 3 and 4. The 13C NMR spectrum of 2 showed 50 peaks for the 58 sp2-carbon atoms in the 156.15–137.93 ppm range and two sp3-carbon atom peaks of the fullerene cage at 68.28 and 60.01 ppm, and the 13C NMR spectra of 3 and 4 displayed at least 52 peaks between 156.04–135.95 ppm for the 56 sp2-carbon atoms and four peaks between 90.31–56.52 ppm for the four sp3-carbon atoms of the fullerene skeleton, agreeing with their C1 symmetry. The UV-vis spectrum of 2 showed a broad absorption band at 446 nm, which resembled those of other 1,4-adducts of C60 [35,40,41]. The UV-vis spectrum of 3 exhibited two strong absorption bands at 254 and 324 nm, together with three weak absorption bands at 405, 431 and 690 nm, which were similar to those of 1,2,3,16-adducts in the literature [26,27,30,31,32,33,35,37,38]. However, in the UV-vis spectrum of product 4, three strong absorption bands at 250, 268 and 330 nm, together with five weak absorption bands at 409, 450, 510, 591 and 672 nm were observed, and were very similar to those of 1,4,9,25-adducts in the literature [32,35].
The single crystal of 3 was obtained by slow evaporation of its carbon disulfide (CS2) solution at room temperature. The crystal structure unambiguously demonstrated that the oxazolidinone moiety was located at a [5,6]-bond (C2–C3) of the C60 skeleton (Figure 2). One of the benzyl groups was connected to C1, and the other one was attached to the C16 position and was distant from other three addend sites. Due to their sp3 character, the four functionalized carbon atoms (C1, C2, C3 and C16) of the fullerene skeleton were uplifted from the spherical surface notably. The single-crystal structure clearly established that the molecular structure of product 3 possessed a 1,2,3,16-addition pattern. Disappointingly, the attempts to obtain the single crystals of 2 and 4 failed. According to the previous literature [26,27,28,29,30,31,32,33,35], the carbon-heteroatom bond of C60-fused heterocycles would break after accepting two electrons, and the most negatively charged carbon atom among the non-functionalized carbons of the fullerene cage was resided at the para position of the addend, which was the most likely site to react with electrophile. As seen from the structure of 3, the C16 was located at the para position of C3. Therefore, electroreduction led to the breakage of the C−O bond followed by rearrangement of the heterocycle moiety from a [6,6]-bond to a [5,6]-bond on the fullerene cage.
Based on the previous literature [26,27,28,29,30,31,32,33,35,42], a possible mechanism for the formations of 2, 3, and 4 from the reaction of 12– with BnBr is shown in Scheme 2. After acceptance of two electrons, fullerooxazolidinone 1 is reduced by CPE and undergoes C60–O bond breakage to afford the ring-opened dianion 12−, with one negative charge located at the carbamic oxygen atom and another charge mainly distributed on the para position of the carbon attached with the addend, which is prone to react with BnBr to generate intermediate I [26,27,28,29,30,31,32,33,35]. Subsequently, the intermediate I can proceed via either decarboxylation process to afford II [42] or ring-closing process to the adjacent [5,6]-bond to generate III [26,27,28,29,30,31,32,33,35]. Then, a protonation process of II affords 2, while III can react with the second BnBr to give 1,2,3,16-adduct 3 and 1,4,9,25-adduct 4 controlled by the electronic and steric effects.
Suitable energy band alignment facilitates charge transport from the perovskite film to electrodes in PSC devices [43]. [6,6]-Phenyl-C61-butyric acid methyl ester (PCBM) is a fullerene derivative that has been widely applied in PSC devices [7,8,9,10,11,43]. Therefore, the energy levels of the lowest unoccupied molecular orbital (LUMO) and the highest occupied molecular orbital (HOMO) of products 1–4 along with PCBM were obtained through differential pulse voltammetry (DPV) and CV (Figure 1, Figure 3a and Figures S22–S25) combined with UV-vis absorption spectroscopy (Figure 3b). The DPV studies revealed that the first reduction potentials (E1) of 1, 2, 3, and 4 were −1.028, −1.096, −1.148 and −1.051 V vs. Fc/Fc+, respectively. Hence, the LUMO energy levels of 1, 2, 3, and 4 were calculated to be −3.772, −3.704, −3.652 and −3.749 eV, respectively [44,45] (Table 1). According to the optical bandgaps correlated with the absorption onsets in the UV-vis spectra at 679, 687, 690 and 672 nm for 2, 3 and 4, the corresponding HOMO energy levels of 1, 2, 3, and 4 were calculated to be −5.598, −5.509, −5.449 and −5.594 eV, respectively [44,46,47]. It could be found that the energy levels of 1, 2, 3, and 4 were also comparable to those of PCBM, indicating that they are promising materials in solar cell devices [7, 8, 9, 10, 11].

3. Materials and Methods

3.1. General Information

All electrochemical measurements and reactions were performed under an atmosphere of argon atmosphere using a Shanghai Chenhua CHI620E workstation. The electrolyte TBAP was recrystallized from absolute ethanol and then dried in a vacuum at 40 °C prior to use. Other chemicals were obtained commercially and used without further purification. CV measurements were performed in a conventional three-electrode cell. A 2 mm diameter platinum disc electrode and a platinum wire auxiliary electrode were used as working and counter electrodes, respectively, and the reference electrode was saturated calomel electrode (SCE). CPE was carried out on a potentiostat/galvanostat using an “H” type cell. Two platinum gauze (15 mm × 30 mm) electrodes served as working and counter electrodes, respectively, and were separated by a sintered glass frit. The SCE was separated from the bulk of the solution by a fritted-glass bridge of low porosity which contained the solvent/supporting electrolyte mixture.

3.2. Generation of Dianion 12−

0.01 mmol of 1 dissolved in 15.0 mL of anhydrous 1,2-C6H4Cl2 solution containing 0.1 M TBAP was added into an “H” type cell. After bubbling with argon for 30 min at 15 °C, the solution was electroreduced by CPE at –1.09 V. When the theoretical number of coulombs (1.93 C) was reached, the electrolysis was terminated after about 1 h, and a dark-green solution of 12− was obtained.

3.3. Synthesis of Compounds 2–4

Synthesis of compounds 2, 3, and 4 with 50 equiv. of BnBr: The dianion 12− was obtained by electroduction from N-p-tolyl-fullerooxazolidinone 1 (8.7 mg, 0.01 mmol), and then reacted with NaH (57–63% oil dispersion, 8.0 mg, 0.20 mmol) and BnBr (60.0 μL, 0.50 mmol). After the solution was kept stirring at 15 °C for 1 h, the resulting mixture was directly filtered through a silica gel (200–300 mesh) plug with CS2/CH2Cl2 (1:1 v/v) to remove TBAP and insoluble material. Then, the solvents were removed with a rotary evaporator in vacuo. Next, the residue combined from the two runs was further separated on a silica gel column (300–400 mesh) with CS2/CH2Cl2 (4:1 v/v) as the eluent to afford compound 2 (5.8 mg, 32%), compound 3 (4.5 mg, 21%), and compound 4 (0.8 mg, 4%) along with unreacted 1 (2.4 mg, 14%) and decomposed C60 (2.6 mg, 18%).
Synthesis of compounds 2, 3, and 4 with 100 equiv. of BnBr: The dianion 12− was obtained by electroduction from N-p-tolyl-fullerooxazolidinone 1 (8.7 mg, 0.01 mmol), and then reacted with NaH (57–63% oil dispersion, 8.0 mg, 0.20 mmol) and BnBr (120.0 μL, 1.00 mmol). After the solution was kept stirring at 15 °C for 1 h, the resulting mixture was directly filtered through a silica gel (200–300 mesh) plug with CS2/CH2Cl2 (1:1 v/v) to remove TBAP and insoluble materials, and then removed the solvent with a rotary evaporator in vacuo. Next, the residue combined from the two runs was further separated on a silica gel column (300–400 mesh) with CS2/CH2Cl2 (4:1 v/v) as the eluent to afford compound 2 (4.2 mg, 23%), compound 3 (6.2 mg, 29%), and compound 4 (0.6 mg, 3%) along with unreacted 1 (1.7 mg, 10%) and decomposed C60 (3.0 mg, 21%). When the reaction time was prolonged to 10 h, the same procedure gave compound 2 (0.7 mg, 4%), compound 3 (8.5 mg, 40%), and compound 4 (2.9 mg, 14%) along with decomposed C60 (3.1 mg, 22%).

3.4. Single-Crystal Growth and Characterization of 3

Black block crystals of 3 were obtained by slow evaporation of the CS2 solution of 3 at room temperature. Single-crystal X-ray diffraction data were collected on a diffractometer (SuperNova, Rigaku, Rigaku Polska Sp. Z oo UI, Wroclaw, Poland) equipped with a CCD area detector using graphite-monochromated Cu Kα radiation (λ = 1.54184 Å) in the scan range 8.174° < 2θ < 150.64°. Using Olex2, the structure was solved with the ShelXT structure solution program using Intrinsic Phasing and refined with the ShelXL refinement package using Least Squares minimization. Crystallographic data have been deposited in the Cambridge Crystallographic Data Centre as deposition number CCDC 2163434.

3.5. CVs and DPVs of Compounds 1–4 along with PCBM

Compounds 1–4 or PCBM (1.0 mM) dissolved in anhydrous 1,2-C6H4Cl2 solution containing 0.1 M TBAP and ferrocene (1.0 mM) as reference were added into an electrochemical cell under an argon atmosphere at 25 °C, while the CV measurements of 1 (1.0 mM) and dianion 12− at 15 °C. CV measurements were then undertaken at a scan rate of 50 mV s−1. The parameters of DPV: step potential: 4 mV; pulse amplitude: 50 mV; pulse duration: 0.05 s; pulse period: 0.5 s.

4. Conclusions

In conclusion, benzylation of the electrochemically generated dianionic N-p-tolyl-fullerooxazolidinone with benzyl bromide affords a ring-opened mono-benzylated 1,4-adduct 2, bis-benzylated 1,2,3,16-adduct 3 and 1,4,9,25-adduct 4. The product distribution can be manipulated by altering the reaction conditions. The structural assignments for products 2–4 are established by spectroscopic data and single-crystal X-ray crystallography. A possible reaction mechanism for the formation of the three types of adducts is proposed. The present work provides a new avenue for the electrochemical functionalization of C60-fused heterocycles.

Supplementary Materials

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/nano12132281/s1, General information; Characterization of compounds 2–4; Figure S1. 1H NMR (400 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 2; Figure S2. 13C NMR (101 MHz, 1:1 CS2/CDCl3) of compound 2; Figure S3. Expanded 13C NMR (101 MHz, 1:1 CS2/CDCl3) of compound 2; Figure S4. Expanded 13C NMR (101 MHz, 1:1 CS2/CDCl3) of compound 2; Figure S5. Expanded 13C NMR (101 MHz, 1:1 CS2/CDCl3) of compound 2; Figure S6. 1H NMR (400 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 3; Figure S7. 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 3; Figure S8. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 3; Figure S9. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 3; Figure S10. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 3; Figure S11. 1H NMR (400 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 4; Figure S12. 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 4; Figure S13. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 4; Figure S14. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 4; Figure S15. Expanded 13C NMR (101 MHz, CS2 with DMSO-d6 as the external deuterium lock) of compound 4; Figure S16. UV-vis spectrum of compound 1 in CHCl3; Figure S17. UV-vis spectrum of compound 2 in CHCl3; Figure S18. UV-vis spectrum of compound 3 in CHCl3; Figure S19. UV-vis spectrum of compound 4 in CHCl3; Figure S20. UV-vis spectrum of PCBM in CHCl3; Figure S21. CV of dianion 12– (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP at 15 °C. The parameters of CV: scan rate: 50 mV s−1; initial potential: –1.09 V; initial scan polarity: negative or positive; Figure S22. CV of compound 2 (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference at 25 °C. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks label the ferrocene/ferrocenium; Figure S23. CV of compound 3 (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference at 25 °C. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks label the ferrocene/ferrocenium; Figure S24. CV of compound 4 (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference at 25 °C. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks label the ferrocene/ferrocenium; Figure S25. CV of PCBM (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference at 25 °C. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks label the ferrocene/ferrocenium; Table S1. Crystal Data and Structure Refinement for Compound 3.

Author Contributions

Investigation, writing—original draft preparation, X.-X.Y.; data collection, X.-X.Y., C.N., S.-Q.Y. and B.-C.Z.; Conceptualization, funding acquisition, supervision, writing—review and editing, G.-W.W. All authors have read and agreed to the published version of the manuscript.

Funding

This research was funded by National Natural Science Foundation of China (22071231 and 21772189) and the Fundamental Research Funds for the Central Universities (WK2060000029).

Data Availability Statement

The data presented in this study are available in the article and Supplementary Materials.

Conflicts of Interest

The authors declare no conflict of interest.

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Figure 1. Cyclic voltammogram of 1 (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks * label the ferrocene/ferrocenium.
Figure 1. Cyclic voltammogram of 1 (1.0 mM) recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP with ferrocene (1.0 mM) as reference. The parameters of CV: scan rate: 50 mV s−1; initial potential: 0.0 V; initial scan polarity: negative. The asterisks * label the ferrocene/ferrocenium.
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Scheme 1. Reaction of the electrochemically generated 12− with BnBr under different conditions.
Scheme 1. Reaction of the electrochemically generated 12− with BnBr under different conditions.
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Figure 2. ORTEP diagram of 3 with 30% thermal ellipsoids. The solvent CS2 molecule is omitted for clarity.
Figure 2. ORTEP diagram of 3 with 30% thermal ellipsoids. The solvent CS2 molecule is omitted for clarity.
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Scheme 2. Proposed mechanism for the formations of 2, 3, and 4.
Scheme 2. Proposed mechanism for the formations of 2, 3, and 4.
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Figure 3. (a) DPVs of 1–4 along with PCBM recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP. The asterisks label the ferrocene/ferrocenium. (b) UV-vis absorption spectra of 1–4 along with PCBM in CHCl3. The inset displays the expanded range of 500–750 nm. All curves of DPVs and UV-vis absorption spectra are shifted vertically for clarity.
Figure 3. (a) DPVs of 1–4 along with PCBM recorded in 1,2-C6H4Cl2 containing 0.1 M TBAP. The asterisks label the ferrocene/ferrocenium. (b) UV-vis absorption spectra of 1–4 along with PCBM in CHCl3. The inset displays the expanded range of 500–750 nm. All curves of DPVs and UV-vis absorption spectra are shifted vertically for clarity.
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Table
Table 1. Characteristic potential values and energy levels of compounds 1–4 along with PCBM derived from DPV and UV-vis absorption spectroscopy.
Table 1. Characteristic potential values and energy levels of compounds 1–4 along with PCBM derived from DPV and UV-vis absorption spectroscopy.
CompdE1a
(V)		λonset b (nm)Eg,optc (eV)LUMO Level d (eV)HOMO Level e (eV)
1−1.0286791.826−3.772−5.598
2−1.0966871.805−3.704−5.509
3−1.1486901.797−3.652−5.449
4−1.0516721.845−3.749−5.594
PCBM−1.1646951.784−3.636−5.420
a Versus ferrocene/ferrocenium. b Attained from UV-vis spectra. c Eg,opt = 1240/λonset [44,47]. d Estimated using the following equation: LUMO level = −(4.8 + E1) eV [44,45]. e HOMO level = (LUMO − Eg,opt) eV [44,46].
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Yan, X.-X.; Niu, C.; Ye, S.-Q.; Zhao, B.-C.; Wang, G.-W. Electrochemically Promoted Benzylation of [60]Fullerooxazolidinone. Nanomaterials 2022, 12, 2281. https://doi.org/10.3390/nano12132281

AMA Style

Yan X-X, Niu C, Ye S-Q, Zhao B-C, Wang G-W. Electrochemically Promoted Benzylation of [60]Fullerooxazolidinone. Nanomaterials. 2022; 12(13):2281. https://doi.org/10.3390/nano12132281

Chicago/Turabian Style

Yan, Xing-Xing, Chuang Niu, Shi-Qi Ye, Bo-Chen Zhao, and Guan-Wu Wang. 2022. "Electrochemically Promoted Benzylation of [60]Fullerooxazolidinone" Nanomaterials 12, no. 13: 2281. https://doi.org/10.3390/nano12132281

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