Label-Free Detection of DNA via Surface-Enhanced Raman Spectroscopy Using Au@Ag Nanoparticles
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Instruments
2.3. Preparation of Au Seeds
2.4. Preparation of Core–Shell Au@AgNPs
2.5. SERS Detection DNA Based on Au@AgICNPs
3. Results and Discussion
3.1. Characterization of Au@AgNPs
3.2. Reproducibility and Quantification Detection of the Same Sequence dsDNA
3.3. Quantitative Detection of Single Bases of dsDNA
3.4. Time Stability Detection of dsDNA Base on Au@AgINPs
3.5. Detection of Different DNA Structures
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Zhang, T.; Quan, X.; Cao, N.; Zhang, Z.; Li, Y. Label-Free Detection of DNA via Surface-Enhanced Raman Spectroscopy Using Au@Ag Nanoparticles. Nanomaterials 2022, 12, 3119. https://doi.org/10.3390/nano12183119
Zhang T, Quan X, Cao N, Zhang Z, Li Y. Label-Free Detection of DNA via Surface-Enhanced Raman Spectroscopy Using Au@Ag Nanoparticles. Nanomaterials. 2022; 12(18):3119. https://doi.org/10.3390/nano12183119
Chicago/Turabian StyleZhang, Ting, Xubin Quan, Naisi Cao, Zhaoying Zhang, and Yang Li. 2022. "Label-Free Detection of DNA via Surface-Enhanced Raman Spectroscopy Using Au@Ag Nanoparticles" Nanomaterials 12, no. 18: 3119. https://doi.org/10.3390/nano12183119