Effect of Europium Substitution on the Structural, Magnetic and Relaxivity Properties of Mn-Zn Ferrite Nanoparticles: A Dual-Mode MRI Contrast-Agent Candidate
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Coprecipitation Synthesis of Mn0.6Zn0.4EuxFe2−xO4
2.3. Hydrothermal Synthesis of Mn0.6Zn0.4EuxFe2−xO4
2.4. PF-127 Coating
2.5. X-ray Diffraction
2.6. Transmission Electron Microscopy
2.7. Magnetic Characterization
2.7.1. Vibrating Sample Magnetometer
2.7.2. Curie Temperature
2.8. Fourier-Transform Infrared Spectroscopy
2.9. Elemental Analysis
2.10. Colloidal Stability
2.11. Relaxometery Measurements
3. Results and Discussion
3.1. Structural Characterization
3.1.1. X-ray Diffraction Study
3.1.2. TEM Analysis
3.1.3. Fourier-Transform Infrared Spectra
3.2. Magnetic Properties
3.3. Colloidal Stability
3.4. Relaxometery Measurements
3.4.1. Effect of Surface Design on Relaxivities
3.4.2. Effect of Eu Substitution on Relaxivities
4. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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x Values | Crystallite Size | Lattice Constant | (emu/g) | Tc (°C) |
---|---|---|---|---|
0.00 | 32 | 8.462 | 55 | 261 |
0.02 | 33 | 8.466 | 58 | - |
0.04 | 30 | 8.462 | 56 | 238 |
0.06 | 28 | 8.466 | - | - |
0.08 | 36 | 8.466 | 54 | - |
0.10 | 23 | 8.457 | 48 | 183 |
0.15 | - | - | 45 | - |
x Values | |||
---|---|---|---|
0.00 | 1.73 ± 0.16 | 263 ± 31 | 152 |
0.02 | 2.05 ± 0.24 | 300 ± 70 | 146 |
0.08 | 5.9 ± 0.71 | 207 ± 19 | 35 |
0.10 | 8.4 ± 1.2 | 157 ± 16 | 18.7 |
0.15 | 11.6 ± 1.44 | 130 ± 16 | 11.2 |
Reference | Structure | Ms (emu/g) | ||
---|---|---|---|---|
Zahraee et al. [65] | MZF@Citric acid | 53 | 4 | 132 |
Zahraee et al. [65] | MZF-PEG | 49 | 3 | 79 |
Junzhao et al. [66] | MZF@4sPCL-b-P(MEO2MA-co-OEGMA) | 59 | 1.28 | 138 |
Tayebe et al. [67] | MZF@PEG | - | - | 88 |
Soraya et al. [30] | MZF@PEG | 60 | - | 314 |
Name | Structure | Dh(nm) | B0(T) | r2/r1 | ||
---|---|---|---|---|---|---|
Resovist | Carboxydextran-coated USPIOs | 60 | 3 | 4.6 | 143 | 31.08 |
Feridex | Dextran-coated SPIOs | 150 | 3 | 4.1 | 93 | 22.68 |
Gadomer | Gd-DTOA | 30 | 3 | 13 | 23 | 1.76 |
Magnevist | Gd-DTPA | - | 3 | 3.1 | 3.7 | 1.19 |
Ferucarbotran® (SHU-555A) | Carboxydextran-coated USPIOs | 60 | 3 | 7.3 | 57 | 7.8 |
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Saeidi, H.; Mozaffari, M.; Ilbey, S.; Dutz, S.; Zahn, D.; Azimi, G.; Bock, M. Effect of Europium Substitution on the Structural, Magnetic and Relaxivity Properties of Mn-Zn Ferrite Nanoparticles: A Dual-Mode MRI Contrast-Agent Candidate. Nanomaterials 2023, 13, 331. https://doi.org/10.3390/nano13020331
Saeidi H, Mozaffari M, Ilbey S, Dutz S, Zahn D, Azimi G, Bock M. Effect of Europium Substitution on the Structural, Magnetic and Relaxivity Properties of Mn-Zn Ferrite Nanoparticles: A Dual-Mode MRI Contrast-Agent Candidate. Nanomaterials. 2023; 13(2):331. https://doi.org/10.3390/nano13020331
Chicago/Turabian StyleSaeidi, Hamidreza, Morteza Mozaffari, Serhat Ilbey, Silvio Dutz, Diana Zahn, Gholamhassan Azimi, and Michael Bock. 2023. "Effect of Europium Substitution on the Structural, Magnetic and Relaxivity Properties of Mn-Zn Ferrite Nanoparticles: A Dual-Mode MRI Contrast-Agent Candidate" Nanomaterials 13, no. 2: 331. https://doi.org/10.3390/nano13020331