Sensors Based on Molecularly Imprinted Polymers in the Field of Cancer Biomarker Detection: A Review
Abstract
:1. Introduction
2. Molecularly Imprinted Polymers
- (A)
- The preparation of MIPs requires the interaction of a template (target molecule) that interacts with the functional groups of the monomer and a cross-linking agent.
- (B)
- Polymerization is initiated, and then the template molecule is removed from the acquired polymer, leaving behind the imprinted cavities to bind to the specific target.
- (C)
2.1. MIP Synthesis Methods
2.1.1. Bulk Polymerization
2.1.2. Precipitation Polymerization
2.1.3. Emulsion Polymerization
2.1.4. Surface Printing
2.1.5. Core-Shell Molecular Printing
2.1.6. Solid-Phase Printing
3. Molecular Imprinting Polymers Used in Sensors for Cancers
3.1. Detection of Lung Cancer
3.2. Breast Cancer Detection
3.3. Detection of Cancer of the Digestive System
3.4. Detection of Cancer of the Reproductive System
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Quezada, C.; Samhitha, S.S.; Salas, A.; Ges, A.; Barraza, L.F.; Blanco-López, M.C.; Solís-Pomar, F.; Pérez-Tijerina, E.; Medina, C.; Meléndrez, M. Sensors Based on Molecularly Imprinted Polymers in the Field of Cancer Biomarker Detection: A Review. Nanomaterials 2024, 14, 1361. https://doi.org/10.3390/nano14161361
Quezada C, Samhitha SS, Salas A, Ges A, Barraza LF, Blanco-López MC, Solís-Pomar F, Pérez-Tijerina E, Medina C, Meléndrez M. Sensors Based on Molecularly Imprinted Polymers in the Field of Cancer Biomarker Detection: A Review. Nanomaterials. 2024; 14(16):1361. https://doi.org/10.3390/nano14161361
Chicago/Turabian StyleQuezada, Camila, S. Shiva Samhitha, Alexis Salas, Adrián Ges, Luis F. Barraza, María Carmen Blanco-López, Francisco Solís-Pomar, Eduardo Pérez-Tijerina, Carlos Medina, and Manuel Meléndrez. 2024. "Sensors Based on Molecularly Imprinted Polymers in the Field of Cancer Biomarker Detection: A Review" Nanomaterials 14, no. 16: 1361. https://doi.org/10.3390/nano14161361