Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue
Abstract
:1. Introduction
2. Materials and Methods
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Healthy (N = 10, 59%) | Oral Leukoplakia (N = 7, 41%) | p-Value | ||
---|---|---|---|---|
Gender | Male | 6 (60%) | 3 (43%) | 0.637 |
Female | 4 (40%) | 4 (57%) | ||
Age | 20–30 | 3 (30%) | 0 (0%) | 0.045 |
40–60 | 5 (50%) | 2 (29%) | ||
60–80 | 2 (20%) | 5 (71%) | ||
Race | Asian | 4 (40%) | 1 (14%) | 0.338 |
White | 6 (60%) | 6 (86%) |
Healthy (N = 10, 59%) | Oral Leukoplakia (N = 7, 41%) | p-Value | |
---|---|---|---|
Group A | 3049 (152); 3014 [2972, 3084]; (2870, 3430) | 2270 (529); 2238 (1832, 2685]; (1630,2987) | 0.001 |
Group B | 3336 (123); 3326 [3288, 3358]; (3091, 3545) | 2745 (306); 2922 [2608, 2964]; (2170,2979) | 0.0001 |
Group C | 2867 (230); 2850 [2766, 3046]; (2376, 3138) | 1618 (241); 1609 [1570, 1752]; (1154,1921) | 0.0008 |
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Wan, H.-H.; Zhu, H.; Chiang, C.-C.; Li, J.-S.; Ren, F.; Tsai, C.-T.; Liao, Y.-T.; Neal, D.; Katz, J.; Esquivel-Upshaw, J.F. Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue. Biosensors 2024, 14, 281. https://doi.org/10.3390/bios14060281
Wan H-H, Zhu H, Chiang C-C, Li J-S, Ren F, Tsai C-T, Liao Y-T, Neal D, Katz J, Esquivel-Upshaw JF. Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue. Biosensors. 2024; 14(6):281. https://doi.org/10.3390/bios14060281
Chicago/Turabian StyleWan, Hsiao-Hsuan, Haochen Zhu, Chao-Ching Chiang, Jian-Sian Li, Fan Ren, Cheng-Tse Tsai, Yu-Te Liao, Dan Neal, Joseph Katz, and Josephine F. Esquivel-Upshaw. 2024. "Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue" Biosensors 14, no. 6: 281. https://doi.org/10.3390/bios14060281