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Article
Peer-Review Record

In Vitro Activity of Ceftolozane-Tazobactam and Other Antibiotics against Pseudomonas aeruginosa Infection-Isolates from an Academic Medical Center in Thailand

Antibiotics 2022, 11(6), 732; https://doi.org/10.3390/antibiotics11060732
by Woraphot Tantisiriwat 1,*, Jirawat Buppanharun 1, Chatchai Ekpanyaskul 1, Kwanchai Onruang 2, Thitiya Yungyuen 3, Pattarachai Kiratisin 3 and Somchai Santiwatanakul 2
Reviewer 1:
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Antibiotics 2022, 11(6), 732; https://doi.org/10.3390/antibiotics11060732
Submission received: 27 April 2022 / Revised: 25 May 2022 / Accepted: 26 May 2022 / Published: 30 May 2022

Round 1

Reviewer 1 Report

Overall report: I like the topic about looking at antimicrobial resistance(AMR) in resource limited settings. AMR is a serious problem and needs global intervention . I feel studies like these will help create more awareness and traction. 

Flow: Flow of the manuscript and its interest to the reader is satsifactory

Language: satisfactory 

Statistical methods: Appropriate

Content validity: In the age of indiscrimate use of antimicrobials and subsequent AMR, I feel this is a good study 

Author Response

Thank you very much for the review and comment.

Kob Kun Krub

 

Woraphot Tantisiriwat, MD

Reviewer 2 Report

Thank you for the article. The article can be accepted in its current form, but for my own curiosity, would you mind elaborating on the fact, of how the clinical data detected the contamination.  Otherwise, I have no other suggestion. 

Author Response

Thank you very much for the review.  We used the clinical information together with the laboratory/imaging results and the antibiotic use for the situations to decide the contaminations or infections.

Sincerely,

Woraphot Tantisiriwat, MD

Woraphot

Reviewer 3 Report

Overall an interesting paper on the antibiotics targeting PA in vitro in Thailand. I have attached a PDF with changes required to spelling etc. before acceptance for publication.

Comments for author File: Comments.pdf

Author Response

Thank you very much for the review and correction for the manuscript.

 I have corrected the manuscipt as suggestion (appeared in red color)

Kob Kun Krub,

 

Woraphot Tantisiriwat, MD

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