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Antibiotics
Volume 13
Issue 10
10.3390/antibiotics13100991
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Review

Antibiotic Prophylaxis and Treatment for Cardiac Device Infections

by
Claudio Pandozi
1,†,
Andrea Matteucci
1,2,*,†,
Carlo Pignalberi
1,
Luca Sgarra
3,
Michela Bonanni
2,4,
Marco Valerio Mariani
5,
Vincenzo Mirco La Fazia
6,
Lorenzo Nesti
7,
Stefania Angela Di Fusco
1,
Federico Nardi
8 and
Furio Colivicchi
1
1
Clinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, Italy
2
Department of Experimental Medicine, Tor Vergata University, 00133 Rome, Italy
3
Cardiology Department, Regional General Hospital “F. Miulli”, 70021 Bari, Italy
4
Fondazione Toscana G. Monasterio, Ospedale del Cuore, 54100 Massa, Italy
5
Department of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences “Sapienza” University of Rome, 00185 Rome, Italy
6
Texas Cardiac Arrhythmia Institute, St. David’s Medical Center, Austin, TX 78705, USA
7
Cardiopulmonary Lab, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy
8
Santo Spirito Hospital, 15033 Casale Monferrato, Italy
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Antibiotics 2024, 13(10), 991; https://doi.org/10.3390/antibiotics13100991
Submission received: 30 September 2024 / Revised: 16 October 2024 / Accepted: 17 October 2024 / Published: 18 October 2024
(This article belongs to the Special Issue Antimicrobial Stewardship for Surgical Antibiotic Prophylaxis and Surgical Site Infections)
Versions Notes

Abstract

Cardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and increased healthcare costs. The effective management of these infections involves a combination of appropriate antibiotic therapy and preventive strategies aimed at reducing the risk of infection. The role of antibiotic prophylaxis in infection prevention is crucial, including the emerging use of antibiotic-supported tools and other local antibiotic delivery systems, which may reduce the risk of infection at the device implant site. In this contemporary review, we provide an overview of the prophylactic treatment and different antibiotic regimens for the treatment of CDIs, emphasizing early diagnosis, appropriate choice of antibiotics, and individualized treatment.
Keywords: cardiovascular implantable electronic devices; CIED infection; antibiotic prophylaxis; antibiotic treatments cardiovascular implantable electronic devices; CIED infection; antibiotic prophylaxis; antibiotic treatments

Share and Cite

MDPI and ACS Style

Pandozi, C.; Matteucci, A.; Pignalberi, C.; Sgarra, L.; Bonanni, M.; Mariani, M.V.; La Fazia, V.M.; Nesti, L.; Di Fusco, S.A.; Nardi, F.; et al. Antibiotic Prophylaxis and Treatment for Cardiac Device Infections. Antibiotics 2024, 13, 991. https://doi.org/10.3390/antibiotics13100991

AMA Style

Pandozi C, Matteucci A, Pignalberi C, Sgarra L, Bonanni M, Mariani MV, La Fazia VM, Nesti L, Di Fusco SA, Nardi F, et al. Antibiotic Prophylaxis and Treatment for Cardiac Device Infections. Antibiotics. 2024; 13(10):991. https://doi.org/10.3390/antibiotics13100991

Chicago/Turabian Style

Pandozi, Claudio, Andrea Matteucci, Carlo Pignalberi, Luca Sgarra, Michela Bonanni, Marco Valerio Mariani, Vincenzo Mirco La Fazia, Lorenzo Nesti, Stefania Angela Di Fusco, Federico Nardi, and et al. 2024. "Antibiotic Prophylaxis and Treatment for Cardiac Device Infections" Antibiotics 13, no. 10: 991. https://doi.org/10.3390/antibiotics13100991

APA Style

Pandozi, C., Matteucci, A., Pignalberi, C., Sgarra, L., Bonanni, M., Mariani, M. V., La Fazia, V. M., Nesti, L., Di Fusco, S. A., Nardi, F., & Colivicchi, F. (2024). Antibiotic Prophylaxis and Treatment for Cardiac Device Infections. Antibiotics, 13(10), 991. https://doi.org/10.3390/antibiotics13100991

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