The Israeli Phage Bank (IPB)
Abstract
:1. Introduction
2. Methods and Results
2.1. Bacteria Collection
2.2. Phage Isolation
2.3. Phage Characterization
2.4. IBP Phage Collection
2.5. The Phage Database
2.6. Bank Activities
3. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Phage Collection Name | Number of Phages | Hosts | Link |
---|---|---|---|
Adaptive phage therapy (APT) phage bank | ~1000 | Mainly the ESKAPE pathogens | http://www.aphage.com/the-science/ |
The Felix d’Hérelle Reference Center for Bacterial Viruses | >400 | A few dozen hosts | https://www.phage.ulaval.ca/en/phages-catalog/ |
The Bacteriophage Bank of Korea | ~1000 | A few dozen hosts | http://www.phagebank.or.kr/intro/eng_intro.jsp |
Leibniz Institute—DSMZ (German Collection of Microorganisms and Cell Cultures) | ~300 | Unknown | https://www.dsmz.de/collection/collection-experts |
ATCC Bacteriophage Collection | ~400 | A few dozen hosts | https://www.atcc.org/search#q=phage&sort=relevancy&f:productcategoryFacet=[Bacteria%20%26%20Phages]&f:listofapplicationsFacet=[Bacteriophage] |
NCTC Bacteriophage Collection | >100 | Streptococcus ssp Staphylococcus ssp Campylobacter | https://www.phe-culturecollections.org.uk/products/bacteria/bacteriophages.aspx |
Hatfull Lab Phage Collection | >15,000 | Species from Actinobacteria phylum | https://phagesdb.org/ http://www.hatfull.org/sea-phages |
TUDelft | Unknown | Unknown | https://www.tudelft.nl/en/delft-university-fund/ |
P.H.A.G.E | Unknown | Unknown | http://www.p-h-a-g-e.org/ |
Israeli Phage Bank (IPB) | >300 | 16 different species | https://ronenhazanlab.wixsite.com/hazanlab/the-404-israeli-phage-bank |
Bacteria | Number of Srains |
---|---|
Acinetobacter baumanii | 12 |
Bacillus anthracis | 1 |
Burkholderia cepacia | 2 |
Burkholderia contaminans | 2 |
Burkholderia lata | 1 |
Others Burkholderia ssp | 20 |
Enterobacter cloacae | 8 |
Enterococcus faecalis | 15 |
Enterococcus faecium | 10 |
Escherichia coli | 8 |
Klebsiella pneumoniae | 10 |
Mycobacterium abscessus | 6 |
Propionibacterium acnes | 36 |
Providencia rettgeri | 21 |
Providencia stuartii | 20 |
Pseudomonas aeruginosa | 120 |
Pseudomonas stutzeri | 2 |
Pseudomonas syringae | 1 |
Salmonella enterica | 2 |
Shigella ssp | 30 |
Staphylococcus aureus | 40 |
Streptococcus mutans | 15 |
Total | 382 |
Bacteria Strain | Clinical Strains | Phages | Percentage of Coverage | Minimum Phages Require for Coverage |
---|---|---|---|---|
Staphylococcus aureus | 20 | 25 | 100% | 1 |
Klebsiella pneumoniae | 8 | 30 | 100% | 2 |
Pseudomonas aeruginosa | 100 | 54 | 100% | 9 |
Pseudomonas stutzeri | 2 | 6 | 100% | 1 |
Enterobacter spp | 7 | 20 | 100% | 3 |
Burkholderia spp | 23 | 15 | 90% | 5 |
Burkholderia lata | 1 | 2 | 100% | 1 |
Enterococcus faecalis + Enterococcus faecium | 8 | 38 | 100% | 1 |
Streptococcus mutans | 15 | 1 | 100% | 1 |
Acinetobacter baumannii | 8 | 19 | 100% | 2 |
Propionibacterium acnes | 36 | 22 | 86% | 1 |
Providencia spp | 35 | 10 | 100% | 3 |
Escherichia coli | 5 | 25 | 100% | 1 |
Bacillus anthracis | 1 | 6 | 100% | 1 |
Salmonella | 30 | 1 | 100% | 1 |
Shigella | 2 | 12 | 100% | 1 |
Mycobacterium abscessus | 6 | 3 | 100% | 1 |
Total | 307 | 289 | 97% | 35 |
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Yerushalmy, O.; Khalifa, L.; Gold, N.; Rakov, C.; Alkalay-Oren, S.; Adler, K.; Ben-Porat, S.; Kraitman, R.; Gronovich, N.; Shulamit Ginat, K.; et al. The Israeli Phage Bank (IPB). Antibiotics 2020, 9, 269. https://doi.org/10.3390/antibiotics9050269
Yerushalmy O, Khalifa L, Gold N, Rakov C, Alkalay-Oren S, Adler K, Ben-Porat S, Kraitman R, Gronovich N, Shulamit Ginat K, et al. The Israeli Phage Bank (IPB). Antibiotics. 2020; 9(5):269. https://doi.org/10.3390/antibiotics9050269
Chicago/Turabian StyleYerushalmy, Ortal, Leron Khalifa, Naama Gold, Chani Rakov, Sivan Alkalay-Oren, Karen Adler, Shira Ben-Porat, Reut Kraitman, Niv Gronovich, Kerem Shulamit Ginat, and et al. 2020. "The Israeli Phage Bank (IPB)" Antibiotics 9, no. 5: 269. https://doi.org/10.3390/antibiotics9050269