Titanium Meshes in Guided Bone Regeneration: A Systematic Review

Round 1

Reviewer 1 Report

the authors attempted to assess the use of titanium meshes during guided bone regeneration by analyzing the bone quantity, mesh exposure, and success/survival rates of the implants. the study design looks sound, however, attention to the following points is recommended.

1. the abstract need to be re-written? it does not reflect the exact paper. the success rate needs to be mentioned. the complications and your recommendations!
2. in the introduction section, the authors should disclose any previous review paper on this topic to highlight the novelty of the current review.
3. figure 1 is not clear. the text is too small.
4. table 2 and 3: the assignment for the signs should be revisited. i.e., (+) for high and (-) for low risk. (-) can not be seen!.
5. what was the recommendations to reduce the risk of mesh exposure according to the studies?
6. The discussion section covers topics including non-resorbable mesh, mesh exposure, implant survival rate, and limitations of the current study. sections related to the complications and statistics are unnecessary, all can be summarized or referred to available tables.
7. The discussion section needs to be re-written, it is too wordy!
8. the text can be reduced remarkably by referring to the tables, it is not necessary to repeat the tables in the text!
9. the grammar should be double-checked by an expert!

Author Response

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Author Response File: Author Response.docx

Reviewer 2 Report

Dear Authors,

I have read your paper "Titanium meshes in guided bone regeneration: A systematic review" carefully.

PRISMA is used correctly. Explanations are clear and the review is easy to read.

But there is no information about type of the titanium meshes.

1. Please, add information about type of the titanium meshes. In the ref. 16-18 the Ti-meshes were different type.  Describe more about thickness and geometry. 
2. Is there effect of the thickness and geometry of the mesh on the regeneration.
3.  Here and there, there is a mention of Ti-meshes without providing any pictures. Please include them in the review (if it possible). 

The paper can be accepted for publication only after major improvements.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Round 2

Reviewer 2 Report

Dear Authors,

I have read your modified paper "Titanium meshes in guided bone regeneration: A systematic review" carefully.

After correction the explanations are clear and the paper is easy to read.

I can recommend the Editor to accept this revised manuscript to be published in Coatings.