Imipramine Increases Norepinephrine and Serotonin in the Salivary Glands of Rats
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Chemicals
2.3. In Vivo Microdialysis in Anesthetized Rats
2.4. Quantification of Monoamines in Dialysates
2.5. Statistical Analyses
3. Results
3.1. Conditions for Optimal Dialysis Perfusion Rate In Vitro
3.2. Monoamines in Dialysates from Submandibular Glands of Rats
3.3. Time Course of Norepinephrine and Serotonin Levels in Dialysate after Probe Implantation
3.4. Infusion of High-K+ Solution
3.5. Infusion of Imipramine
3.6. Intraperitoneal Administration of Imipramine
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Shirose, K.; Yoshikawa, M.; Kan, T.; Miura, M.; Watanabe, M.; Matsuda, M.; Kobayashi, H.; Kawaguchi, M.; Ito, K.; Suzuki, T. Imipramine Increases Norepinephrine and Serotonin in the Salivary Glands of Rats. Biology 2024, 13, 679. https://doi.org/10.3390/biology13090679
Shirose K, Yoshikawa M, Kan T, Miura M, Watanabe M, Matsuda M, Kobayashi H, Kawaguchi M, Ito K, Suzuki T. Imipramine Increases Norepinephrine and Serotonin in the Salivary Glands of Rats. Biology. 2024; 13(9):679. https://doi.org/10.3390/biology13090679
Chicago/Turabian StyleShirose, Kosuke, Masanobu Yoshikawa, Takugi Kan, Masaaki Miura, Mariko Watanabe, Mitsumasa Matsuda, Hiroyuki Kobayashi, Mitsuru Kawaguchi, Kenji Ito, and Takeshi Suzuki. 2024. "Imipramine Increases Norepinephrine and Serotonin in the Salivary Glands of Rats" Biology 13, no. 9: 679. https://doi.org/10.3390/biology13090679